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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,951–20,975 of 27,380 studies, newest first · page 839 of 1096.

February 2010 25

  1. 2010-02-24

    DHA may prevent age-related dementia

    ✓ Peer-reviewed Disease mechanisms The Journal of nutrition

    Key finding: Clinical trials suggest that DHA or fish oil alone can slow early stages of progression, but these effects may be apolipoprotein E genotype specific, and larger trials with very early stages are required to prove efficacy.

    Full summary, score breakdown and related studies → Original source

  2. 2010-02-24

    Interactions between age, stress and insulin on cognition: implications for Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Key finding: Glucocorticoid secretion associated with early life stress may contribute to the variability of the aging process and to the development of neuro- and psychopathologies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-02-23

    Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: The results presented here provide a molecular basis for the Abeta-induced cognitive deficits and, moreover, show that rapamycin, an FDA approved drug, improves learning and memory and reduces Abeta and Tau pathology.

    Full summary, score breakdown and related studies → Original source

  4. 2010-02-22

    Early intervention for cognitive decline: can cognitive training be used as a selective prevention technique?

    ✓ Peer-reviewed Prevention trials International psychogeriatrics

    Key finding: CT offers promise as a preventive therapeutic technique in healthy older adults and particularly as a secondary prevention method for "at risk" groups. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2010-02-22

    VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

    ✓ Peer-reviewed Lewy body dementia Autophagy

    Key finding: We determined that VCP deficiency by RNAi-mediated knockdown or overexpression of dominant-negative VCP results in significant accumulation of immature autophagic vesicles, some of which are abnormally large, acidified and exhibit cathepsin B activity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-02-20

    Apolipoprotein-E forms dimers in human frontal cortex and hippocampus

    ✓ Peer-reviewed Genetics BMC neuroscience

    Key finding: In apoE3 homozygous samples, approximately 12% of apoE was present as a homodimer and approximately 2% was detected as a 43 kDa heterodimer. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2010-02-20

    Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Biochimica et biophysica acta

    Key finding: Based on the research conducted so far in the area of lipid peroxidation, it is suggested that lipid accessible antioxidant molecules could be a promising therapeutic approach to treat or slow progression of MCI and AD.

    Full summary, score breakdown and related studies → Original source

  8. 2010-02-19

    Characteristics of Medicare Part D Beneficiaries Who Reach the Drug Benefit Threshold in Both of the First Two Years of the Part D Benefit

    ✓ Peer-reviewed Health systems and care delivery Medical Care

    Key finding: Those who reached the DBT in both years had higher morbidity and utilization. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2010-02-19

    Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

    ⚠ Retracted — do not rely on it Lewy body dementia PloS one

    Key finding: This study supports the notion that defects in the autophagy pathway and more specifically in mTor and Atg7 are associated with neurodegeneration in DLB cases and alpha-synuclein transgenic models and supports the possibility that modulators of the autophagy pathway might have potential therapeutic effects. +4 more findings

    Scored 32 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  10. 2010-02-18

    Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: study in 200 consecutively recruited individuals

    ✓ Peer-reviewed Vascular contributions Stroke

    Key finding: Our data suggest that cardiovascular risk factors may modulate the clinical expression of CADASIL. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2010-02-18

    Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study

    ✓ Peer-reviewed How common it is Stroke

    Key finding: In a large community-based sample of middle-aged adults, BI predicted an increased risk of stroke and dementia independent of vascular risk factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2010-02-17

    Voxelwise genome-wide association study (vGWAS)

    ✓ Peer-reviewed Genetics NeuroImage

    Key finding: By studying only the most associated variant at each voxel, we developed a novel method to address the multiple comparisons problem and computational burden associated with the unprecedented amount of data.

    Full summary, score breakdown and related studies → Original source

  13. 2010-02-17

    Formation and function of apolipoprotein E-containing lipoproteins in the nervous system

    ✓ Peer-reviewed Inflammation and the immune system Biochimica et biophysica acta

    Key finding: Several ATP-binding cassette (ABC) transporters are expressed in the brain, including ABCA1 and ABCG1 which play important roles in the transfer of phospholipids and cholesterol to apo E. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2010-02-16

    Assessment of white matter tract damage in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Human brain mapping

    Key finding: MD values were significantly different among groups in all WM tracts (P values ranging from 0.002 to 0.03), except in the fornix (P = 0.06) and the inferior fronto-occipital fasciculus (P = 0.09). +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2010-02-16

    Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Nature reviews. Neurology

    Key finding: This knowledge has been translated into new therapeutic strategies with putative disease-modifying effects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2010-02-16

    Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery

    ✓ Peer-reviewed How common it is Circulation

    Key finding: Frailty is a risk for postoperative complications and an independent predictor of in-hospital mortality, institutional discharge, and reduced midterm survival.

    Full summary, score breakdown and related studies → Original source

  17. 2010-02-15

    DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease

    ✓ Peer-reviewed Tau biomarkers Brain : a journal of neurology

    Key finding: Both DJ-1 and alpha-synuclein, two proteins critically involved in Parkinson's disease pathogenesis, have been tested as disease biomarkers in several recent studies with inconsistent results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2010-02-14

    Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    ✓ Peer-reviewed Risk factors Nature genetics

    Key finding: We found that FTLD-TDP associates with multiple SNPs mapping to a single linkage disequilibrium block on 7p21 that contains TMEM106B.

    Full summary, score breakdown and related studies → Original source

  19. 2010-02-13

    Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Neuro-degenerative diseases

    Key finding: About hundred years ago, Oskar Fischer proposed that the senile plaques are the consequence of the deposition of a foreign substance that could induce an inflammatory response leading to an abnormal neuritic response of the surrounding neurons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2010-02-11

    Untreated poor vision: a contributing factor to late-life dementia

    ✓ Peer-reviewed Costs and economics American journal of epidemiology

    Key finding: Poor vision was associated with development of dementia (P = 0.0048); individuals with very good or excellent vision at baseline had a 63% reduced risk of dementia (95% confidence interval (CI): 20, 82) over a mean follow-up period of 8.5 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2010-02-10

    n‐3 Omega fatty acids: a review of current knowledge

    ✓ Peer-reviewed Prevention and risk International Journal of Food Science & Technology

    Key finding: Most significantly, the reported protective effect of the n‐3 omega fatty acids in relation to cardiovascular inflammatory diseases and cancer has led people to consider these fatty acids more beneficial than other dietary supplements. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2010-02-10

    Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Higher Abeta deposition is associated with greater longitudinal decline in mental status and verbal memory in the preceding years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2010-02-09

    Amyloid oligomers: formation and toxicity of Abeta oligomers

    ✓ Peer-reviewed Disease mechanisms The FEBS journal

    Key finding: However, accumulating evidence suggests that prefibrillar soluble Abeta oligomers induce AD-related synaptic dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2010-02-09

    Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients

    ✓ Peer-reviewed Hippocampus size on brain scans Neuropharmacology

    Key finding: Although depressive disorders are traditionally considered to have a neurochemical basis, recent studies suggest that impairments of structural plasticity contribute to the volume reductions and the related cognitive changes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2010-02-09

    Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: In the brain, it is a key player in the molecular pathogenesis of Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →