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Factors underlying cognitive decline in old age and Alzheimer's disease: the role of the hippocampus
Jaroudi W, Garami J, Garrido S, Hornberger M, Keri S, Moustafa AA.. Reviews in the neurosciences, 2017-10-01
Topic: Risk, prevention and care in population studies
There are many factors that strongly influence the aetiology, development, and progression of cognitive decline in old age, mild cognitive impairment (MCI), and Alzheimer's disease (AD). These factors include not only different personality traits and moods but also lifestyle patterns (e.g. exercise and diet) and awareness levels that lead to cognitive decline in old age. In this review, we discuss how personality traits, mood states, and lifestyle impact brain and behaviour in older adults. Specifically, our review shows that these lifestyle and personality factors affect several brain regions, including the hippocampus, a region key for memory that is affected by cognitive decline in old age as well as AD. Accordingly, appropriate recommendations are presented in this review to assist individuals in decreasing chances of MCI, dementia, AD, and associated symptoms.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Jaroudi, W., Garami, J., Garrido, S., Hornberger, M., Keri, S., & Moustafa, A. A. (2017). Factors underlying cognitive decline in old age and Alzheimer's disease: the role of the hippocampus. Reviews in the neurosciences. https://doi.org/10.1515/revneuro-2016-0086
Vancouver
Jaroudi W, Garami J, Garrido S, Hornberger M, Keri S, Moustafa AA. Factors underlying cognitive decline in old age and Alzheimer's disease: the role of the hippocampus. Reviews in the neurosciences. 2017. doi:10.1515/revneuro-2016-0086. PMID: 28422707.
BibTeX
@article{jaroudi2017-28422707,
author = {Jaroudi, W. and Garami, J. and Garrido, S. and Hornberger, M. and Keri, S. and Moustafa, A. A.},
title = {{Factors underlying cognitive decline in old age and Alzheimer's disease: the role of the hippocampus}},
journal = {Reviews in the neurosciences},
year = {2017},
doi = {10.1515/revneuro-2016-0086},
pmid = {28422707},
url = {https://doi.org/10.1515/revneuro-2016-0086}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- There are many factors that strongly influence the aetiology, development, and progression of cognitive decline in old age, mild cognitive impairment (MCI), and Alzheimer's disease (AD).
- These factors include not only different personality traits and moods but also lifestyle patterns (e.g. exercise and diet) and awareness levels that lead to cognitive decline in old age.
- In this review, we discuss how personality traits, mood states, and lifestyle impact brain and behaviour in older adults.
- Specifically, our review shows that these lifestyle and personality factors affect several brain regions, including the hippocampus, a region key for memory that is affected by cognitive decline in old age as well as AD.
- Accordingly, appropriate recommendations are presented in this review to assist individuals in decreasing chances of MCI, dementia, AD, and associated symptoms.
Why it matters
This review discusses how personality traits, mood, and lifestyle factors such as exercise and diet affect the hippocampus and may influence cognitive decline in old age, mild cognitive impairment, and Alzheimer's disease. It offers recommendations but presents no new treatment, cure, or prevention results.
Study details
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Reviews in the neurosciences) |
| Journal's citation record | 1 / 4 | Reviews in the Neurosciences: journal h-index 108 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2017 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 167 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 15.2 citations a year over 11 year(s) since 2017 |
| Impact for its field and year | 3 / 6 | Cited 5.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 3 / 4 | Cited 68 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Ahmed A. Moustafa: h-index 52 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of East Anglia: institution h-index 759 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 3 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 28422707) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 43 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1515/revneuro-2016-0086
- PubMed: 28422707
- Original source →
- Free full text: SZTE Publicatio Repozitórium (University of Szeged) →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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