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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,901–12,925 of 27,380 studies, newest first · page 517 of 1096.

April 2019 25

  1. 2019-04-24

    Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer's Disease

    ✓ Peer-reviewed Drug development Frontiers in aging neuroscience

    Key finding: The first clinical trials show promising results and are a proof of concept that utilizing such treatments is valid.

  2. 2019-04-24

    Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies

    ✓ Peer-reviewed Biomarkers Frontiers in nutrition

    Key finding: Interestingly, several observations indicate that the calibrated assumption of correct doses of vitamins such as folic acid, vitamin B6, vitamin B12, and betaine may control HHCys-related conditions.

  3. 2019-04-24

    Cognitive outcomes following coronary artery bypass grafting: A systematic review and meta-analysis of 91,829 patients

    ✓ Peer-reviewed Clinical safety International journal of cardiology

    Key finding: The results of this meta-analysis demonstrate that cognitive impairment and delirium are major issues in CABG patients which require specific attention. +1 more finding

  4. 2019-04-24

    Association Between Periodontitis and Cognitive Impairment in Adults: A Systematic Review

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in neurology

    Key finding: The results should, however, be interpreted cautiously due to the limited number of studies.

  5. 2019-04-24

    Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease

    ✓ Peer-reviewed Biomarkers Frontiers in neurology

    Key finding: The failure to find an association between PET amyloid deposition and cognitive impairment in a moderately large sample, particularly given that it was enriched with PD-MCI patients at risk of dementia, suggests that amyloid pathology is not the primary driver of cognitive impairment and dementia in most patients with PD.

  6. 2019-04-23

    Smartphone-Based Interventions to Foster Simple Activity and Personal Satisfaction in People With Advanced Alzheimer's Disease

    ✓ Peer-reviewed Cognitive tests and assessment American journal of Alzheimer's disease and other dementias

    Key finding: All participants had significant increases in independent response frequencies, level of personal satisfaction, and heart rates during program sessions as opposed to baseline or control sessions. +1 more finding

  7. 2019-04-23

    Obesity, Brain Volume, and White Matter Microstructure at MRI: A Cross-sectional UK Biobank Study

    ✓ Peer-reviewed Long-term cohort studies Radiology

    Key finding: Obesity has been associated with increased risk of accelerated cognitive decline and dementia, which suggests underlying neurobiological changes. +3 more findings

  8. 2019-04-22

    Structured Genome-Wide Association Studies with Bayesian Hierarchical Variable Selection

    ✓ Peer-reviewed Genetics Genetics

    Key finding: It becomes increasingly important in using genome-wide association studies (GWAS) to select important genetic information associated with qualitative or quantitative traits. +1 more finding

  9. 2019-04-22

    Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

    ✓ Peer-reviewed Disease mechanisms Molecules (Basel, Switzerland)

    Key finding: Various neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), among others, can be the result of biochemical alteration (due to oxidative stress) in bimolecular components.

  10. 2019-04-22

    Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease

    ✓ Peer-reviewed Getting a diagnosis Alzheimer's research & therapy

    Key finding: The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ 42 ), total Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau 181 ) have proven diagnostic accuracy for mild cognitive impairment and dementia due to Alzheimer's Disease (AD). +4 more findings

  11. 2019-04-21

    Associations between sleep duration and cognitive impairment in mild cognitive impairment

    ✓ Peer-reviewed Risk factors Journal of sleep research

    Key finding: The prevalence of mild cognitive impairment (MCI) increases among elderly people and is associated with a high risk of dementia. +3 more findings

  12. 2019-04-21

    An Old Man's Love

    ✓ Peer-reviewed Risk factors Academic Emergency Medicine

    Key finding: She's waiting for me to come home, I heard again. +4 more findings

  13. 2019-04-21

    Natural Language Processing for the Identification of Silent Brain Infarcts From Neuroimaging Reports

    ✓ Peer-reviewed Digital health tools JMIR medical informatics

    Key finding: Features for rule-based systems, including significant words and patterns related to SBI, were generated using pointwise mutual information. +2 more findings

  14. 2019-04-20

    Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Acta neuropathologica

    Key finding: One of the key molecules involved in microglial activation is galectin-3 (gal3), and we demonstrate here for the first time a key role of gal3 in AD pathology. +3 more findings

  15. 2019-04-19

    Formaldehyde, Epigenetics, and Alzheimer's Disease

    ✓ Peer-reviewed Drug development Chemical research in toxicology

    Key finding: Recent studies suggest that elevation of FA in the body by endogenous and/or exogenous exposure may play important roles in AD development. +1 more finding

  16. 2019-04-19
  17. 2019-04-19

    Taking Care of the Dyad: Frequency of Caregiver Assessment Among Veterans with Dementia

    ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society

    Key finding: Healthcare providers identified caregivers in most of the sample, but less than 50% assessed their well-being and needs. +1 more finding

  18. 2019-04-18

    Exercise as a prescription for patients with various diseases

    ✓ Peer-reviewed Prevention trials Journal of sport and health science

    Key finding: Because each sport has its own set of characteristics and physiological complications that tend to occur during exercise training, the effects and underlying mechanisms of exercise remain unclear. +4 more findings

  19. 2019-04-18

    A Single-Channel EEG-Based Approach to Detect Mild Cognitive Impairment via Speech-Evoked Brain Responses

    ✓ Peer-reviewed Digital health tools IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

    Key finding: Best results (leave-one-out cross-validation accuracy 87.9%, sensitivity 84.8%, specificity 95%, and F score 85%) were obtained using support vector machine (SVM) method with radial basis kernel (RBF) (sigma = 10/cost = 10 2 ). +2 more findings

  20. 2019-04-17

    Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model

    ✓ Peer-reviewed Disease mechanisms Free radical biology & medicine

    Key finding: Nevertheless, molecular mechanisms by which VLCFA result in toxicity remain unclear.

  21. 2019-04-17

    Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders

    ✓ Peer-reviewed Clinical safety Internal medicine (Tokyo, Japan)

    Key finding: Nutrition combined with nasogastric tube feeding or percutaneous endoscopic gastrostomy feeding should be considered owing to the increased risk of aspiration and difficulty administrating oral nutrition.

  22. 2019-04-17

    Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis

    ✓ Peer-reviewed Risk factors BMJ (Clinical research ed.)

    Key finding: In analyses that addressed bias due to reverse causation, physical inactivity was not associated with all-cause dementia or Alzheimer's disease, although an indication of excess dementia risk was observed in a subgroup of physically inactive individuals who developed cardiometabolic disease. +1 more finding

  23. 2019-04-17

    The silent epidemic of chronic pain in older adults

    ✓ Peer-reviewed Caregiving Progress in neuro-psychopharmacology & biological psychiatry

    Key finding: Chronic pain is highly prevalent among older adults where it is associated with significant suffering, disability, social isolation, and greater costs and burden to health care systems. +1 more finding

  24. 2019-04-16

    Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway

    ✓ Peer-reviewed Biomarkers Frontiers in pharmacology

    Key finding: Alzheimer's disease (AD), a progressive neurodegenerative disease characterized by impairments of cognitive function as a result of synaptic deficits and neuronal loss, is associated with inflammation. +3 more findings

  25. 2019-04-15

    The role of gut microbiota in pathogenesis of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Journal of applied microbiology

    Key finding: The diversity of the gut microbiota declines in the elderly and in patients with Alzheimer's disease (AD). +4 more findings

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