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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,151–14,175 of 27,380 studies, newest first · page 567 of 1096.

March 2018 25

  1. 2018-03-20

    Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer's disease dementia in mild cognitive impairment

    ✓ Peer-reviewed Tau biomarkers Alzheimer's research & therapy

    Key finding: Cerebrospinal fluid (CSF) biomarkers have been used to increase the evidence of underlying Alzheimer's disease (AD) pathology in mild cognitive impairment (MCI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-03-20

    Soluble TREM2 and biomarkers of central and peripheral inflammation in neurodegenerative disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroimmunology

    Key finding: Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial receptor involved in innate immunity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2018-03-19

    Process Evaluation of the NYU Caregiver Intervention-Adult Child

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Adult children receiving the NYUCI-AC completed a mean of 5.19 individual and family counseling sessions; it took on average a little over 11 months to do so. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2018-03-19

    Falls and Hospitalizations Among Persons With Dementia and Associated Caregiver Emotional Difficulties

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Over 20% of caregivers reported high levels of care-related emotional difficulty. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2018-03-19

    Causes of hyperhomocysteinemia and its pathological significance

    ✓ Peer-reviewed Risk factors Archives of pharmacal research

    Key finding: The main cause of hyperhomocysteinemia is a dysfunction of enzymes and cofactors associated with the process of homocysteine biosynthesis.

    Full summary, score breakdown and related studies → Original source

  6. 2018-03-19

    TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD

    ✓ Peer-reviewed Brain tissue and pathology Nature neuroscience

    Key finding: Understanding how TDP-43 contributes to neurodegeneration will help direct therapeutic efforts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2018-03-16

    Frailty and the gut

    ✓ Peer-reviewed Disease mechanisms Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    Key finding: A better comprehension of the intestinal dysfunction occurring in the elderly would help in clarifying the mechanisms predisposing frail patients to a higher risk of infectious or inflammatory events. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2018-03-16

    Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?

    ✓ Peer-reviewed Costs and economics NeuroImage. Clinical

    Key finding: In addition to an overview of the results, we briefly outline the methods applied to the concept of resting-state functional connectivity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2018-03-16

    Glucagon like peptide-1 (GLP-1) likes Alzheimer's disease

    ✓ Peer-reviewed Drug development Diabetes & metabolic syndrome

    Key finding: Hyperinsulinemia and insulin resistance, which are known as pathophysiological features of the T2DM, have also been demonstrated to have significant impact on cognitive impairment.

    Full summary, score breakdown and related studies → Original source

  10. 2018-03-16

    The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study

    ✓ Peer-reviewed Long-term cohort studies The Lancet. Neurology

    Key finding: Alzheimer's disease is one of the most heritable diseases in elderly people and the most common type of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2018-03-16

    Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies

    ✓ Peer-reviewed Prevention and risk Pharmacological research

    Key finding: It has been demonstrated that AD, diabetes, obesity, insulin resistance, and cardiovascular disease are strongly interconnected pathologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2018-03-16

    Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Arterial stiffness, measured by PWV, is an emerging risk factor for dementia through its repeated relationships with cognition, cSVD, and Aβ deposition. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2018-03-15

    Dyadic construction of dementia: meta-ethnography and behaviour-process synthesis

    ✓ Peer-reviewed Caregiving Aging & mental health

    Key finding: Seventeen studies were included in the review. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2018-03-15

    Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular medicine (Cambridge, Mass.)

    Key finding: Overexpression of genes on chromosome-21 (Hsa21) is responsible for the pathogenesis of Down syndrome (DS) phenotypic features either in a direct or in an indirect manner since many Hsa21 genes can affect the expression of other genes mapping to different chromosomes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2018-03-15

    DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development European journal of pharmacology

    Key finding: We found that: (1) DA5-CH administration effectively improved working-memory and long-term spatial memory of 9-month-old AD mice in Y-maze and Morris water maze tests; (2) DA5-CH also reduced hippocampal amyloid senile plaques and phosphorylated tau protein levels; (3) DA5-CH basically reversed the deficits in hippocampal late-phase long-term potentiation; (4) DA5-CH up-regulated the levels of p-PI3K and p-AKT growth factor kinases and prevented excessive activation of p-GSK3β in the hippocampus of APP/PS1 mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2018-03-15

    Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

    ✓ Peer-reviewed TREM2 and immune genetics Circulation research

    Key finding: It is assumed that atherosclerotic arteries contain several macrophage subsets endowed with specific functions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2018-03-15

    Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors

    ✓ Peer-reviewed Lewy body dementia Cell

    Key finding: Our results present CasRx as a programmable RNA-binding module for efficient targeting of cellular RNA, enabling a general platform for transcriptome engineering and future therapeutic development.

    Full summary, score breakdown and related studies → Original source

  18. 2018-03-14

    Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: Among Swedish women, a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2018-03-13

    Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease

    ✓ Peer-reviewed Genetics Annals of clinical and translational neurology

    Key finding: A variant in AKAP9, p.R434W, segregated significantly with LOAD in two large families (OR = 5.77, 95% CI: 1.07-30.9, P = 0.041). +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2018-03-13

    AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease

    ✓ Peer-reviewed Genetics Human gene therapy. Clinical development

    Key finding: Population studies have shown that an inheritance of the apolipoprotein E (APOE) variant APOE4 allele increases the risk of developing AD, whereas APOE2 homozygotes are protected from late-onset AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2018-03-13

    Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease

    ✓ Peer-reviewed Genetics Scientific data

    Key finding: Patients with Alzheimer's disease (AD) and Parkinson's disease (PD) often have overlap in clinical presentation and brain neuropathology suggesting that these two diseases share common underlying mechanisms.

    Full summary, score breakdown and related studies → Original source

  22. 2018-03-13

    Hearing loss and the risk of dementia in later life

    ✓ Peer-reviewed Prevention and risk Maturitas

    Key finding: Hearing loss may be associated with increased risk of dementia in later life and therefore could be a modifiable risk factor, given the availability of efficacious interventions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2018-03-12

    A fundamental conflict of care: Nurses' accounts of balancing patients' sleep with taking vital sign observations at night

    ✓ Peer-reviewed End-of-life care Journal of clinical nursing

    Key finding: In this study, we found an early warning score algorithm focused on deterioration prevention did not account for long-term management or palliative care trajectories. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2018-03-12

    The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates

    ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in medicine

    Key finding: Thus, clinically different, classical ARDs/GSs are, indeed, the result of peculiar combinations of alterations regarding the same, limited set of basic mechanisms shared with the aging process. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2018-03-10

    High complement levels in astrocyte-derived exosomes of Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology Annals of neurology

    Key finding: Astrocytes fulfill neuronal trophic roles normally, but are transformed in Alzheimer disease (AD) into A1-type reactive astrocytes that may destroy neurons through unknown mechanisms. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →