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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,401–10,425 of 27,380 studies, newest first · page 417 of 1096.

March 2021 25

  1. 2021-03-20

    End-of-life care for people with advanced dementia and pain: a qualitative study in Swedish nursing homes

    ✓ Peer-reviewed End-of-life care BMC nursing

    Key finding: This study highlights the need for nursing homes to employ specialist nurses who have been trained in the appropriate knowledge and skills to deal with the challenges of end-of-life care for people with advanced dementia and pain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2021-03-19

    NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases

    ✓ Peer-reviewed Disease mechanisms Redox biology

    Key finding: Impaired mitochondrial metabolism has been associated with mitochondrial dysfunction in brain damage of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-03-19

    Informal Dementia Caregivers: Current Technology Use and Acceptance of Technology in Care

    ✓ Peer-reviewed Cognitive tests and assessment International journal of environmental research and public health

    Key finding: The majority of participants were women (63%), and large number of them used technological devices such as a smartphone (91%) or computer (81%). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-03-19

    Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Patients with Alzheimer dementia from the Swedish Dementia Registry starting on ChEIs within 3 months of the dementia diagnosis were included and compared to nontreated patients with Alzheimer dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-03-19

    Potential value and impact of data mining and machine learning in clinical diagnostics

    ✓ Peer-reviewed Digital health tools Critical reviews in clinical laboratory sciences

    Key finding: It has previously been shown that data mining can improve the prediction and diagnostic precision of type 2 diabetes mellitus.

    Full summary, score breakdown and related studies → Original source

  6. 2021-03-18

    Do self-reported hearing and visual impairments predict longitudinal dementia in older adults?

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: HI and VI at baseline were reported by 30.3% and 16.6% of individuals, respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-03-18

    A novel tau-based rhesus monkey model of Alzheimer's pathogenesis

    ✓ Peer-reviewed TREM2 and immune genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Alzheimer's disease (AD) is a devastating condition with no effective treatments, with promising findings in rodents failing to translate into successful therapies for patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-03-17

    Increased choroidal thickness in adults with Down syndrome

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: ChT was increased in people with DS (pwDS) compared to Ctrl. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-03-17

    Tablet-Based Automatic Assessment for Early Detection of Alzheimer's Disease Using Speech Responses to Daily Life Questions

    ✓ Peer-reviewed Cognitive tests and assessment Frontiers in digital health

    Key finding: We found that in daily life questions, around 80% of speech features showing significant differences between CN and MCI overlapped those showing significant differences in both our study and other studies using neuropsychological tasks, but the number of significantly different features as well as their effect sizes from life questions decreased compared with those from neuropsychological tasks. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-03-17

    Microglial phagocytosis of neurons in neurodegeneration, and its regulation

    ✓ Peer-reviewed Genetics Journal of neurochemistry

    Key finding: RNA-seq and genome-wide association (GWAS) studies have linked multiple phagocytic genes to neurodegenerative diseases, and knock-out of phagocytic genes has been found to protect against neurodegeneration in animal models, suggesting that excessive microglial phagocytosis contributes to neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  11. 2021-03-17

    Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroscience research

    Key finding: We examined the role of MAPK signaling in microglia using a preclinical model of AD pathology and quantitative proteomics studies of postmortem human brains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-03-17

    A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer's dementia

    ✓ Peer-reviewed Caregiving Alzheimer's research & therapy

    Key finding: A significant drug-placebo difference on the ADAS-Cog12 favoring GV-971 was present at each measurement time point, measurable at the week 4 visit and continuing throughout the trial. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-03-16

    Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population

    ✓ Peer-reviewed Prevention trials Journal of the American Geriatrics Society

    Key finding: In the present study, higher adherence to MeDi was associated with a reduced risk for dementia and cognitive decline in a traditional Mediterranean population. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-03-16

    Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: We identified two major sites in the β-helix of PHFs and SFs and a third major site in the C-shaped cavity of SFs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-03-15

    A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease

    ✓ Peer-reviewed Clinical trials Drugs & aging

    Key finding: No significant difference in ADAS-Cog13, CDR Sum of Boxes (CDR-SOB), or FAQ scores were found between treatment groups at 3 and 6 months. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-03-15

    Affective symptoms and regional cerebral tau burden in early-stage Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging International journal of geriatric psychiatry

    Key finding: There were significant associations (p < 0.05) between the NPI variables (total score, Affective factor) and entorhinal and precuneus tau across all participants. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-03-15

    National Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: New consensus diagnostic criteria for TES were developed with a primary goal of facilitating future CTE research. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2021-03-15

    Spreading of Beta-Amyloid in Organotypic Mouse Brain Slices and Microglial Elimination and Effects on Cholinergic Neurons

    ✓ Peer-reviewed Biomarkers Biomolecules

    Key finding: The "spreading hypothesis" suggests that a pathological protein (similar to prions) spreads over the entire brain. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-03-14

    Smoking and Alcohol Consumption Following a New Dementia Diagnosis

    ✓ Peer-reviewed Prevention and risk The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Older adults with a new dementia diagnosis were 2.8 times more likely to reduce alcohol consumption than those without such a diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-03-13

    Efficacy of Multidomain Intervention Against Physio-cognitive Decline Syndrome: A Cluster-randomized Trial

    ✓ Peer-reviewed Prevention trials Archives of gerontology and geriatrics

    Key finding: Backgrounds To investigate the efficacy of a community group-based intervention among community-dwelling older adults with physio-cognitive decline syndrome (PCDS). +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-03-13

    Donanemab in Early Alzheimer's Disease

    ✓ Peer-reviewed Treatments The New England journal of medicine

    Key finding: In patients with early Alzheimer's disease, donanemab resulted in a better composite score for cognition and for the ability to perform activities of daily living than placebo at 76 weeks, although results for secondary outcomes were mixed. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-03-12

    Cognitive reserve and Alzheimer's biological continuum: clues for prediction and prevention of dementia

    ✓ Peer-reviewed Risk factors Minerva medica

    Key finding: It is considered the result of a balance between processes of cellular damage and repair, and its description raised much interest in predicting and preventing cognitive decline in aging and Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2021-03-12

    Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Diabetes, elevated fasting glucose, central obesity, and heart age greater than chronological age were associated with rate of decline in processing speed during midlife. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-03-12

    Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

    ✓ Peer-reviewed Genetics Nature communications

    Key finding: Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer's disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unknown, impeding a mechanistic understanding of AD pathogenesis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-03-12

    Characteristics of Parkinson’s Disease in Patients with and without Cognitive Impairment

    ✓ Peer-reviewed Health systems and care delivery Journal of Parkinson s Disease

    Key finding: Comorbidity indices for patients with cognitive impairment increased during the 6-year study period, especially after the index. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →