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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,026–13,050 of 27,380 studies, newest first · page 522 of 1096.

March 2019 25

  1. 2019-03-13

    Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life

    ✓ Peer-reviewed Prevention trials The Cochrane database of systematic reviews

    Key finding: We found no studies on our primary outcome of global cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-03-13

    Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and 18F-FDG-PET imaging

    ✓ Peer-reviewed Cognitive tests and assessment NeuroImage. Clinical

    Key finding: Therefore, it is of great interest to determine which biomarkers should be combined to accurately predict conversion from mild cognitive impairment (MCI) to AD dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-03-13

    Computerised cognitive training for preventing dementia in people with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment The Cochrane database of systematic reviews

    Key finding: Selection criteria We included randomised controlled trials (RCTs) and quasi-RCTs in which cognitive training via interactive computerised technology was compared with an active or inactive control intervention. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-03-13

    Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-03-13

    Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

    ✓ Peer-reviewed Prevention and risk The Journal of steroid biochemistry and molecular biology

    Key finding: High level of serum cholesterol has been found to positively correlate with an increased risk of dementia and some studies have reported a decreased prevalence of AD in patients taking cholesterol-lowering drugs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-03-12

    Aβ and tau structure-based biomarkers for a blood- and CSF-based two-step recruitment strategy to identify patients with dementia due to Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The primary Aβ-based blood biomarker funnels individuals with suspected AD for subsequent validation of the diagnosis by structure-based combined analysis of the CSF biomarkers Aβ and tau. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2019-03-12

    Signs and Symptoms of Low-Intake Dehydration Do Not Work in Older Care Home Residents-DRIE Diagnostic Accuracy Study

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: This study consolidates evidence that commonly used signs and symptoms of dehydration lack even basic levels of diagnostic accuracy in older adults, implying that many who are dehydrated are not being identified, thus compromising their health and well-being. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-03-12

    Strengths and support of older people affected by precarity in South Louisiana

    ✓ Peer-reviewed Risk factors International Journal of Older People Nursing

    Key finding: The findings demonstrate five central negative conditions of precarity that older people had to manage: (a) loss and discontinuity of home-based healthcare services, (b) stress after loss or disruption of social support, (c) problems of poverty, (d) cognitive impairment and declining health and (e) stress of eviction. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-03-12

    Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

    ✓ Peer-reviewed Prevention and risk Pharmacology & therapeutics

    Key finding: Risk factors for AD including aging, the female sex, as well as carrying an APOE4 genotype. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-03-11

    Dementia and Parkinson's Disease: Similar and Divergent Challenges in Providing Palliative Care

    ✓ Peer-reviewed End-of-life care Frontiers in neurology

    Key finding: However, for both conditions, the protracted disease trajectories complicate conceptualization of palliative care through different stages of the disease, with pertinent questions such as when to offer what interventions pro-actively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-03-11

    Retinal Microvascular and Neurodegenerative Changes in Alzheimer's Disease and Mild Cognitive Impairment Compared with Control Participants

    ✓ Peer-reviewed Brain scans and imaging Ophthalmology. Retina

    Key finding: Alzheimer's participants showed significantly reduced macular VD, PD, and GC-IPL thickness compared with MCI and controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-03-11

    Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue

    ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications

    Key finding: Our data indicate that MK-6240 strongly binds to neurofibrillary tangles in Alzheimer disease but does not seem to bind to a significant extent to tau aggregates in non-Alzheimer tauopathies, suggesting that it may have a limited utility for the in vivo detection of these pathologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2019-03-11

    Concepts for brain aging: resistance, resilience, reserve, and compensation

    ✓ Peer-reviewed Prevention and risk Alzheimer's research & therapy

    Key finding: A primary goal of research in cognitive impairment and dementia is to understand how some individuals retain sufficient cognitive function for a fulfilling life while many others are robbed of their independence, sometimes their essence, in the last years and decades of life. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-03-09

    Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Redox biology

    Key finding: Increasing evidences support the notion that the impairment of intracellular degradative machinery is responsible for the accumulation of oxidized/misfolded proteins that ultimately results in the deposition of protein aggregates. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-03-09

    Dementia imaging in clinical practice: a European-wide survey of 193 centres and conclusions by the ESNR working group

    ✓ Peer-reviewed Disparities Neuroradiology

    Key finding: Current practice in dementia imaging is fairly homogeneous across Europe, in terms of image acquisition and image interpretation.

    Full summary, score breakdown and related studies → Original source

  16. 2019-03-08

    Amyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: These findings suggest that higher amyloid-β load in cognitively normal individuals with subjective cognitive decline from a memory clinic is associated with lower concurrent global cognition and with faster rate of decline in a variety of cognitive domains.

    Full summary, score breakdown and related studies → Original source

  17. 2019-03-08

    Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

    ✓ Peer-reviewed Disease mechanisms Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Axonal degeneration, synaptic dysfunction, astroglial activation, and altered tau metabolism are involved already in preclinical AD.

    Full summary, score breakdown and related studies → Original source

  18. 2019-03-08

    Dynamic 11C-PiB PET Shows Cerebrospinal Fluid Flow Alterations in Alzheimer Disease and Multiple Sclerosis

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: ANOVA revealed significant group differences in lateral ventricular SUVR across the Alzheimer, mild cognitive impairment, and healthy control groups ( P = 0.004). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2019-03-08

    Therapeutic potentials of plant iridoids in Alzheimer's and Parkinson's diseases: A review

    ✓ Peer-reviewed Genetics European journal of medicinal chemistry

    Key finding: Plant iridoids such as catalpol and its 10-O-trans-p-coumaroyl derivative, geniposide, harpagoside, and loganin, and seco-iridoids, oleuropein and its aglycone and oleocanthal have been found to exhibit significant neuroprotective effect and the property of slowing down the process of neurogedeneration in AD and PD.

    Full summary, score breakdown and related studies → Original source

  20. 2019-03-07

    Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination

    ✓ Peer-reviewed Genetics Accounts of Chemical Research

    Key finding: Hundreds of proteins are known to be citrullinated and hypercitrullination is associated with autoimmune diseases including rheumatoid arthritis (RA), lupus, ulcerative colitis (UC), Alzheimer's disease, multiple sclerosis (MS), and certain cancers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-03-07

    Associations of the metabolic syndrome and its components with cognitive impairment in older adults

    ✓ Peer-reviewed Risk factors BMC geriatrics

    Key finding: Lower HDL-C was significantly associated with a higher odds of cognitive impairment (OR 2.70 per 1 mmol/L reduction; 95% CI 1.25, 5.56; p = 0.011), whereas BMI, TG, glucose and HbA1c were not (all p > 0.05). +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-03-07

    CSF biomarkers and amyloid PET: concordance and diagnostic accuracy in a MCI cohort

    ✓ Peer-reviewed Brain scans and imaging Acta neurologica Belgica

    Key finding: In discordant cases, the clinical diagnosis was most often in agreement with PET results.

    Full summary, score breakdown and related studies → Original source

  23. 2019-03-07

    Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid

    ✓ Peer-reviewed Tau biomarkers Neurobiology of aging

    Key finding: Cross-sectionally, CSF t-tau and p-tau were associated with abnormal Aβ1-42 and APOEε4 but not with sex.

    Full summary, score breakdown and related studies → Original source

  24. 2019-03-07

    Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

    ✓ Peer-reviewed Lewy body dementia Neuron

    Key finding: These findings identify a neuronal cell death mechanism that can be initiated by transient-stress-induced cytosolic de-mixing of TDP-43.

    Full summary, score breakdown and related studies → Original source

  25. 2019-03-06

    The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica communications

    Key finding: Our results reveal a new role for the VAPB-PTPIP51 tethers in neurons and suggest that damage to ER-mitochondria signaling contributes to synaptic dysfunction in Parkinson's disease and FTD/ALS.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →