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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,151–13,175 of 27,380 studies, newest first · page 527 of 1096.

February 2019 25

  1. 2019-02-08

    Advance care plans in dementia: user-centred design

    ✓ Peer-reviewed End-of-life care BMJ supportive & palliative care

    Key finding: Nine cyclical stages were undertaken to achieve the outcome of an ACP guide and template. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2019-02-08

    The Role of NMDA Receptors in Alzheimer's Disease

    ✓ Peer-reviewed Treatments Frontiers in neuroscience

    Key finding: In Alzheimer's disease (AD), early synaptic dysfunction is associated with the increased oligomeric amyloid-beta peptide, which causes NMDAR-dependent synaptic depression and spine elimination.

    Full summary, score breakdown and related studies → Original source

  3. 2019-02-07

    Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk

    ✓ Peer-reviewed TREM2 and immune genetics Journal of molecular biology

    Key finding: In Alzheimer's disease (AD), a majority of risk loci discovered through genome-wide association studies were found in or near genes expressed most highly in microglia leading to the hypothesis that microglia play a much larger role in disease progression than previously thought. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-02-06

    Nursing homes underreport antipsychotic prescribing

    ✓ Peer-reviewed Costs and economics Aging & mental health

    Key finding: Nursing homes underreport their antipsychotic prescribing levels, on average, by 1 percentage point per quarter relative to Medicare Part D claims (0.013, 95% confidence interval (CI), 0.012-0.015; p<.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-02-06

    CPAP Adherence May Slow 1-Year Cognitive Decline in Older Adults with Mild Cognitive Impairment and Apnea

    ✓ Peer-reviewed Mild cognitive impairment Journal of the American Geriatrics Society

    Key finding: Controlling for baseline differences, 1 year of CPAP adherence in MCI +OSA significantly improved cognition, compared with a nonadherent control group, and may slow the trajectory of cognitive decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-02-06

    PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins

    ✓ Peer-reviewed Brain tissue and pathology Cell research

    Key finding: Protein posttranslational modifications (PTMs) are known to regulate RNP granules. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-02-06

    Early versus late MCI: Improved MCI staging using a neuropsychological approach

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Our novel neuropsychological approach improved the staging of MCI by (1) capturing individuals at an early symptomatic stage, (2) minimizing false-positive cases, and (3) identifying a late MCI group further along the disease trajectory. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2019-02-06

    The Role of Movement Analysis in Diagnosing and Monitoring Neurodegenerative Conditions: Insights from Gait and Postural Control

    ✓ Peer-reviewed Digital health tools Brain sciences

    Key finding: We summarise the novel 'big data' approaches that utilise data mining and machine learning techniques to improve disease classification and risk prediction, and conclude with recommendations for future direction.

    Full summary, score breakdown and related studies → Original source

  9. 2019-02-06

    Education and cognitive reserve in old age

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: The results suggest that the contribution of education to cognitive reserve is limited to its association with level of cognitive function before old age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-02-05

    Comparison between amyloid-PET and CSF amyloid-β biomarkers in a clinical cohort with memory deficits

    ✓ Peer-reviewed Tau biomarkers Clinica chimica acta; international journal of clinical chemistry

    Key finding: However, whether and to which extend results of cerebrospinal fluid (CSF) and imaging biomarkers are comparable, is unclear. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-02-05

    The Importance of the Validation of M/EEG With Current Biomarkers in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Frontiers in human neuroscience

    Key finding: In this paper we review what these neurophysiological techniques can add to the early diagnosis of AD, whether results in both modalities are related to each other or not, as well as the need of its validation against current biomarkers.

    Full summary, score breakdown and related studies → Original source

  12. 2019-02-03

    18F-Florbetaben PET/CT to Assess Alzheimer's Disease: A new Analysis Method for Regional Amyloid Quantification

    ✓ Peer-reviewed Brain scans and imaging Journal of neuroimaging : official journal of the American Society of Neuroimaging

    Key finding: Forty-four consecutive patients with clinical evidence of dementia, were retrospectively evaluated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-02-02

    Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

    ✓ Peer-reviewed Genetics Alzheimer s Research & Therapy

    Key finding: PLCG2 expression is restricted primarily to microglia and granule cells of the dentate gyrus. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-02-02

    Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults

    ✓ Peer-reviewed Prevention and risk The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: MBI may be an earlier marker of neurodegenerative disease than MCI, captured at the stage of subjective cognitive decline or before, raising the possibility that MBI represents a novel target for dementia clinical trials or prevention strategies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-02-01

    Evidence-informed practical recommendations for increasing physical activity among persons living with HIV

    ✓ Peer-reviewed Cognitive tests and assessment AIDS

    Key finding: Non-ART polypharmacy is common among PLWH and associated with an increasing risk of hospitalization and mortality [1]; thus, nonpharmacologic management of comorbidities is critical for PLWH who may experience an earlier onset and a greater burden of comorbidities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-02 month only

    Potential retinal biomarkers for dementia: what is new?

    ✓ Peer-reviewed Brain scans and imaging Current opinion in neurology

    Key finding: In terms of the retinal neuronal structure, multiple retinal neuronal layers are significantly thinner in Alzheimer's disease dementia, such as the parapapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GC-IPL). +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-02-01

    Benefits and Challenges of Rare Genetic Variation in Alzheimer's Disease

    ✓ Peer-reviewed Genetics Current genetic medicine reports

    Key finding: It is well established that sporadic Alzheimer's disease (AD) is polygenic with common and rare genetic variation alongside environmental factors contributing to disease.

    Full summary, score breakdown and related studies → Original source

  18. 2019-02-01

    Health Care Utilization and Cost Outcomes of a Comprehensive Dementia Care Program for Medicare Beneficiaries

    ✓ Peer-reviewed Digital health tools JAMA internal medicine

    Key finding: Program participants (n = 382 men, n = 701 women; mean [SD] age, 82.10 [7.90] years; age range 54-101 years) were less likely to be admitted to a long-term care facility (hazard ratio, 0.60; 95% CI, 0.59-0.61) than those not participating in the dementia care program (n = 759 men, n = 1407 women; mean [SD] age, 82.42 [8.50] years; age range, 34-103 years).

    Full summary, score breakdown and related studies → Original source

  19. 2019-02-01

    The role of the gut microbiota in development, function and disorders of the central nervous system and the enteric nervous system

    ✓ Peer-reviewed Disease mechanisms Journal of neuroendocrinology

    Key finding: Furthermore, numerous studies indicate that there is a developmental window early in life during which the gut microbial composition is crucial and perturbation of the gut microbiota during this period causes long-lasting effects on the development of the CNS and the ENS.

    Full summary, score breakdown and related studies → Original source

  20. 2019-02-01

    Families' Experiences With End-of-Life Care in Nursing Homes and Associations With Dying Peacefully With Dementia

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: Families' reports of unpleasant experiences with end-of-life care may inform practice to improve perceived quality of dying of their loved ones. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-02-01

    Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Neuroscience

    Key finding: Emerging evidence suggests that the intricate balance of interactions between neurons, astrocytes, microglia and vascular cells required for healthy brain function becomes perturbed during the disease, with early changes likely protecting neural circuits from damage, followed later by harmful effects when the balance cannot be restored. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2019-02-01

    Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential

    ✓ Peer-reviewed Long-term cohort studies American journal of epidemiology

    Key finding: From the Dutch, population-based Rotterdam Study, 10,348 persons were followed during 1990-2015 for dementia and death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-02-01

    Primary Progressive Aphasias and Apraxia of Speech

    ✓ Peer-reviewed Digital health tools Continuum (Minneapolis, Minn.)

    Key finding: This article reviews two of the primary progressive aphasias (PPAs), disorders characterized by the early and predominant impairment of language, and primary progressive apraxia of speech, a degenerative motor speech disorder that is closely related to PPA.

    Full summary, score breakdown and related studies → Original source

  24. 2019-02-01

    Prevalence, Underlying Causes, and Preventability of Sepsis-Associated Mortality in US Acute Care Hospitals

    ✓ Peer-reviewed How common it is JAMA network open

    Key finding: The study cohort included 568 patients (289 [50.9%] men; mean [SD] age, 70.5 [16.1] years) who died in the hospital or were discharged to hospice.

    Full summary, score breakdown and related studies → Original source

  25. 2019-02-01

    Blood Pressure and Cognitive Decline Over 8 Years in Middle-Aged and Older Black and White Americans

    ✓ Peer-reviewed Disparities Hypertension (Dallas, Tex. : 1979)

    Key finding: In a prospective national study of 22 164 blacks and whites ≥45 years without baseline cognitive impairment or stroke from the REGARDS cohort study (Reasons for Geographic and Racial Differences in Stroke), enrolled 2003 to 2007 and followed through September 2015, we measured changes in cognition associated with baseline systolic and diastolic BP (SBP and DBP), as well as pulse pressure (PP) and mean arterial pressure, and we tested whether age, race, and sex modified the effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →