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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,526–13,550 of 27,380 studies, newest first · page 542 of 1096.

November 2018 7

  1. 2018-11-01

    Prevalence of Aging, Dementia, and Multimorbidity in Older Adults With Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's JAMA neurology

    Key finding: Older Medicare beneficiaries in California with DS, especially those with dementia, have a high level of multimorbidity including several treatable conditions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-11-01

    Family Caregivers of Older Adults, 1999-2015: Trends in Characteristics, Circumstances, and Role-Related Appraisal

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Purpose of study To assess trends in family caregiving between 1999 and 2015. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2018-11-01

    Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study

    ✓ Peer-reviewed Prevention and risk JAMA neurology

    Key finding: Stroke, dementia, and hypertension are associated with late-onset epilepsy; however, the role of other vascular and lifestyle factors remains unclear. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2018-11-01

    Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

    ✓ Peer-reviewed Treatments Nature reviews. Neurology

    Key finding: To date, most preventive interventions have been tested in small groups, have focused on a single lifestyle factor and have yielded negative or modest results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2018-11-01

    Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: The 751 study participants were older (median age [interquartile range], 87 years [51-105 years]), 395 (54%) were women, and 324 (44%) were APOE ε4 carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2018-11-01

    Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: Ann Neurol 2018;84:737-748.

    Full summary, score breakdown and related studies → Original source

  7. 2018-11-01

    Signs and Artifacts in Amyloid PET

    ✓ Peer-reviewed Biomarkers Radiographics : a review publication of the Radiological Society of North America, Inc

    Key finding: Furthermore, preliminary data show that amyloid PET findings alter clinical management in patients who meet the appropriate use criteria. +4 more findings

    Full summary, score breakdown and related studies → Original source

October 2018 18

  1. 2018-10-31

    Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: A distinct combination of E3 ubiquitin ligases and specific chaperones is required to achieve each type of linkage-specific ubiquitination. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-10-30

    Montreal cognitive assessment reflects cognitive reserve

    ✓ Peer-reviewed Risk factors BMC geriatrics

    Key finding: The MoCA reflected total CRIq score (CRI; B = 0.076, P < 0.001), CRI-Education (B = 0.066, P < 0.001), and CRI-Working activity (B = 0.025, P = 0.042), while MMSE reflected total CRI (B = 0.044, P < 0.001) and CRI-Education (B = 0.049, P < 0.001) only. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2018-10-30

    Repurposing Proteostasis-Modifying Drugs to Prevent or Treat Age-Related Dementia: A Systematic Review

    ✓ Peer-reviewed Drug development Frontiers in physiology

    Key finding: Overall 47 trials, 38 animal and 9 human, were isolated for inclusion in this review. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2018-10-30

    Secondary prevention of Alzheimer's dementia: neuroimaging contributions

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: MRI can also be used to assess comorbid vascular pathology and define homogeneous groups for inclusion or for subject stratification. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2018-10-30

    Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

    ✓ Peer-reviewed Prevention trials Translational psychiatry

    Key finding: Higher MeDi score was associated with less Aβ accumulation in our cohort (β = -0.01 ± 0.004, p = 0.0070). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2018-10-30

    Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular syndromology

    Key finding: Building a scientific framework that distills mechanisms involved in the developmental intellectual disability of DS as well as the early-onset component of Alzheimer disease and the several other comorbidities associated with the condition is a challenge that scientists are now tackling using novel technologies and multidisciplinary approaches.

    Full summary, score breakdown and related studies → Original source

  7. 2018-10-30

    Geriatric Telepsychiatry: Systematic Review and Policy Considerations

    ✓ Peer-reviewed Disparities The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: This article will discuss the current barriers to broader implementation of telemedicine for geriatric patients including reimbursement from the Medicare program. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2018-10-29

    Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

    ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications

    Key finding: This study aimed to determine the pattern of [18F]flortaucipir uptake in individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the PRNP F198S mutation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2018-10-29

    Neurogenetic contributions to amyloid beta and tau spreading in the human cortex

    ✓ Peer-reviewed Brain scans and imaging Nature medicine

    Key finding: We found that tau propagation and Aβ propagation patterns were associated with a common genetic profile related to lipid metabolism, in which APOE played a central role, whereas the tau-specific genetic profile was classified as 'axon related' and the Aβ profile as 'dendrite related'.

    Full summary, score breakdown and related studies → Original source

  10. 2018-10-28

    Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase

    ✓ Peer-reviewed Risk genes beyond APOE Cell stress

    Key finding: Genetic evidence strongly suggests that aberrant generation and/or clearance of the neurotoxic amyloid-β peptide (Aβ) is triggering the disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2018-10-27

    Variability in metabolic parameters and risk of dementia: a nationwide population-based study

    ✓ Peer-reviewed Risk factors Alzheimer's research & therapy

    Key finding: A total of 32,901 (1.12%) participants developed dementia, of which 74.4% and 11.0% were attributable to Alzheimer's disease and vascular dementia, respectively, during the median follow-up of 5.5 years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2018-10-25

    Prevalence of and Risk Factors for Urinary Incontinence in Home Hospice Patients

    ✓ Peer-reviewed End-of-life care European urology

    Key finding: Female sex and age were associated with a greater risk of UI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2018-10-25

    Neuroimaging in dementia. Clinical-radiological correlation

    ✓ Peer-reviewed Prevention trials Radiologia

    Key finding: Dementia is a syndrome characterised by chronic, multi-domain, acquired cognitive impairment that causes significant functional limitations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2018-10-25

    CSF soluble TREM2 as a measure of immune response along the Alzheimer's disease continuum

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: The present study explores sTREM2 CSF levels and their associations with other biomarkers and cognitive measures in a prospective AD cohort. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2018-10-25

    Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Systemic vascular health has significant impact on brain structure and function. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2018-10-24

    Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo

    ✓ Peer-reviewed Drug development The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: For some time NFTs were considered the primary cause of synaptic dysfunction and neuronal death, however, more recent evidence suggests that soluble aggregates of tau are key drivers of disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2018-10-24

    Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: We evaluated dementia-free Framingham Heart Study (generation 3) participants (mean age 48.5 years, 46.8% men) who underwent cognitive testing for memory, abstract reasoning, visual perception, attention, and executive function (n = 2,231) and brain MRI (n = 2018) to assess total white matter, lobar gray matter, and white matter hyperintensity volumes and fractional anisotropy (FA) measures. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2018-10-23

    Default Mode Network Complexity and Cognitive Decline in Mild Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging Frontiers in neuroscience

    Key finding: The default mode network (DMN), one of so-called resting-state networks, has been associated with cognitive processes that are directed toward the self, such as introspection and autobiographic memory. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →