alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,276–12,300 of 27,380 studies, newest first · page 492 of 1096.

November 2019 25

  1. 2019-11-27

    Effects of virtual reality-based cognitive training in older adults living without and with mild dementia: a pretest-posttest design pilot study

    ✓ Peer-reviewed Prevention trials BMC research notes

    Key finding: Older adults with mild dementia demonstrated worse baseline cognitive performance than participants without dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-11-26

    Modification of the gut microbiome to combat neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Reviews in the neurosciences

    Key finding: Ample amount of studies being carried out also revealed the involvement of the gut microbiome in enhancing the degree of many neurological disorders, including neurodegenerative diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2019-11-26

    The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in aging neuroscience

    Key finding: A rare variant in TREM2 increases AD risk with an odds ratio comparable to the strongest genetic risk factor apolipoprotein ε4 allele. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-11-26

    Improving shared decision-making in advance care planning: Implementation of a cluster randomized staff intervention in dementia care

    ✓ Peer-reviewed End-of-life care Patient education and counseling

    Key finding: Nursing home staff benefits from this training in shared decision-making.

    Full summary, score breakdown and related studies → Original source

  5. 2019-11-26

    Unexplained regression in Down syndrome: 35 cases from an international Down syndrome database

    ✓ Peer-reviewed Down syndrome and Alzheimer's Genetics in medicine : official journal of the American College of Medical Genetics

    Key finding: Establishing this clinical definition supports future research and investigation of an underlying mechanism.

    Full summary, score breakdown and related studies → Original source

  6. 2019-11-25

    Microvascular pericytes in brain-associated vascular disease

    ✓ Peer-reviewed Vascular contributions Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Key finding: Pericytes are closely related to the cerebrovascular and central nervous system disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-11-25

    Comparison of cholinesterase inhibitor safety in real-world practice

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (New York, N. Y.)

    Key finding: Compared with low-dose donepezil, galantamine use was associated with a lower risk of mortality (adjusted hazard ratio: 0.84, 95% confidence interval: 0.60-1.18), cardiovascular serious adverse events (adjusted hazard ratio: 0.78, 95% confidence interval: 0.62-0.98), and entry into a residential care facility (adjusted hazard ratio: 0.72, 95% confidence interval: 0.59-0.89). +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2019-11-25

    Functional Connectivity between the Resting-State Olfactory Network and the Hippocampus in Alzheimer's Disease

    ✓ Peer-reviewed Long-term cohort studies Brain sciences

    Key finding: AD pathology is known to disrupt brain regions instrumental in olfactory information processing, such as the primary olfactory cortex (POC), the hippocampus, and other temporal lobe structures. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-11-25

    Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Until now, data on the longitudinal trajectories of amyloid accumulation, tau pathology, and brain atrophy over multiple time points remain scarce in DS.

    Full summary, score breakdown and related studies → Original source

  10. 2019-11-23

    Genome-wide association study of hippocampal atrophy rate in non-demented elders

    ✓ Peer-reviewed Genetics Aging

    Key finding: Three single nucleotide polymorphisms (SNPs) (rs4420638, rs56131196, rs157582) in the TOMM40-APOC1 region were associated with hippocampal atrophy rate at genome-wide significance and 3 additional SNPs (in TOMM40 and near MIR302F gene) reached a suggestive level of significance. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2019-11-23

    Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: The Lumipulse G assays show a very good analytical performance that makes them well-suited for CSF clinical routine measurements. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-11-23

    Repetitive transcranial magnetic stimulation for cognitive impairment in Alzheimer's disease: a meta-analysis of randomized controlled trials

    ✓ Peer-reviewed Prevention trials Journal of neurology

    Key finding: Based on the current evidence, rTMS was an effective therapy for cognitive impairment in AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-11-23

    The potential mechanism of postoperative cognitive dysfunction in older people

    ✓ Peer-reviewed Inflammation and the immune system Experimental gerontology

    Key finding: Accumulating attention has been paid to POCD worldwide in pace with the popularization of anesthesia/surgery. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-11-22

    Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Both AD and TDP/HS contribute to hippocampal volume loss in older-old persons, with TDP/HS more strongly associated with hippocampal volume than AD in Alzheimer dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-11-21

    Race, Ethnicity, and Other Risks for Live Discharge Among Hospice Patients with Dementia

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Policies regarding sustained hospice eligibility should account for the variable and protracted end-of-life trajectory of patients with dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-11-21

    Disease-Specific Plan Switching Between Traditional Medicare and Medicare Advantage

    ✓ Peer-reviewed Health systems and care delivery The Permanente Journal

    Key finding: Beneficiaries with a new diagnosis of Alzheimer disease and related dementias, hypertension, and psychiatric disorders had relatively high rates of switching into MA plans and low rates of switching out of MA plans. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-11-21

    Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data

    ✓ Peer-reviewed Digital health tools BMC medical informatics and decision making

    Key finding: The machine learning algorithm for NPTs has suggested potential use as a reference in differentiating cognitive impairment in the clinical setting.

    Full summary, score breakdown and related studies → Original source

  18. 2019-11-20

    Educating Dutch General Practitioners in Dementia Advance Care Planning: A Cluster Randomized Controlled Trial

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: Our educational intervention increased ACP initiation, and the number of nonmedical and medical preferences discussed.

    Full summary, score breakdown and related studies → Original source

  19. 2019-11-20

    NLRP3 inflammasome activation drives tau pathology

    ✓ Peer-reviewed Inflammation and the immune system Nature

    Key finding: Loss of NLRP3 inflammasome function reduced tau hyperphosphorylation and aggregation by regulating tau kinases and phosphatases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2019-11-20

    A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades.

    Full summary, score breakdown and related studies → Original source

  21. 2019-11-20

    Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology

    ✓ Peer-reviewed Caregiving Neuron

    Key finding: Our findings suggest a "feed-forward" mechanism whereby Aβ plaques enhance endogenous α-syn seeding and spreading over time post-injection with mpffs.

    Full summary, score breakdown and related studies → Original source

  22. 2019-11-19

    Recruitment and retention of underrepresented populations in Alzheimer's disease research: A systematic review

    ✓ Peer-reviewed Disparities Alzheimer's & dementia (New York, N. Y.)

    Key finding: Overall, the quantity and quality of available evidence to inform best practices in recruitment, retention, and inclusion of underrepresented populations in ADRD research are low. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-11-19

    Review of Gait, Cognition, and Fall Risks with Implications for Fall Prevention in Older Adults with Dementia

    ✓ Peer-reviewed Clinical safety Dementia and geriatric cognitive disorders

    Key finding: Older people with cognitive impairment are at increased risk of falls; however, fall prevention strategies have limited success in this population. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-11-19

    Prevalence and clinical aspects of mild cognitive impairment in Parkinson's disease: A meta-analysis

    ✓ Peer-reviewed Risk factors Movement disorders : official journal of the Movement Disorder Society

    Key finding: Mild cognitive impairment associated with Parkinson's disease (PD) is a risk factor for the development of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-11-18

    The gut microbiome in neurological disorders

    ✓ Peer-reviewed Disease mechanisms The Lancet. Neurology

    Key finding: Increasing clinical and preclinical evidence implicates the microbiome as a possible key susceptibility factor for neurological disorders, including Alzheimer's disease, autism spectrum disorder, multiple sclerosis, Parkinson's disease, and stroke. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →