Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 12,126–12,150 of 27,380 studies, newest first · page 486 of 1096.
January 2020 25
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2020-01-01
The Area Deprivation Index: A novel tool for harmonizable risk assessment in Alzheimer's disease research
50/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Translational Research & Clinical Interventions
Key finding: Participants in the most disadvantaged neighborhoods (n = 156) were younger, more often female, and less often college-educated or white than those in less disadvantaged neighborhoods (n = 1963). +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
What Does a Post-Pandemic Presidency Mean for Medicare?
15/100 ⚠ Report — not peer-reviewed Health systems and care delivery Public Policy & Aging Report
Key finding: Social isolation and loneliness are associated with significant negative impacts on mental and physical health, including heart disease, stroke, depression, cancer, and dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Three Trends Shaping the Politics of Aging in America
16/100 ⚠ Report — not peer-reviewed Health systems and care delivery Public Policy & Aging Report
Key finding: In fact, average benefits are considered modest compared with the benefits of other developed countries. +4 more findings
Scored 23 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2020-01-01
Diagnosed prevalence of Alzheimer's disease and related dementias in Medicare Advantage plans
48/100 ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Key finding: In 2014 and 2016, the overall prevalence of AD/ADRD diagnoses was 5.6% and 6.5%, respectively. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Time-restricted feeding alters isoflurane-induced memory deficits
32/100 ✓ Peer-reviewed Risk factors Translational Neuroscience
Key finding: Previously, we found that circadian desynchrony was involved in isoflurane-induced cognitive impairment. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
53/100 ✓ Peer-reviewed Inflammation and the immune system Theranostics
Key finding: However, the underlying mechanism is unclear. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint
54/100 ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: Identifying clinical measures that track disease in the earliest stages of frontotemporal lobar degeneration (FTLD) is important for clinical trials. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank
43/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: However, randomized controlled trials have not shown clear evidence that vitamin D supplementation could improve cognitive outcomes. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Telomere Length and the Risk of Alzheimer's Disease: The Rotterdam Study
52/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: Telomere length has received considerable attention as such a marker, because it is easily quantified and it may aid in disentangling the etiology of dementia or serve as predictive marker. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Associations of White Matter Hyperintensities with Cognitive Decline: A Longitudinal Study
54/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: In order to identify whether the volume of WMHs is associated with cognitive decline over years, this longitudinal study involved 818 individuals from the ADNI-2 dataset from August 2010 to May 2017. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium
68/100 ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: We created global rating scoring rules for the CDR ® plus NACC FTLD to detect and track early frontotemporal lobar degeneration (FTLD) and to conduct clinical trials in FTLD. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Type 2 Diabetes Interacts With Alzheimer Disease Risk Factors to Predict Functional Decline
51/100 ✓ Peer-reviewed Tau biomarkers Alzheimer disease and associated disorders
Key finding: The current study examined the interactive effect of type 2 diabetes and Alzheimer disease (AD) risk factors on the rate of functional decline in cognitively normal participants from the Alzheimer's Disease Neuroimaging Initiative. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
The Amyloid, Tau, and Neurodegeneration (A/T/N) Classification Applied to a Clinical Research Cohort with Long-Term Follow-Up
48/100 ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD
Key finding: The unbiased amyloid, tau, and neurodegeneration (A/T/N) classification is designed to characterize individuals in the Alzheimer continuum and is currently little explored in clinical cohorts. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Soluble TREM2 and Inflammatory Proteins in Alzheimer's Disease Cerebrospinal Fluid
47/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD
Key finding: We studied 303 participants, including 89 controls, 135 mild cognitive impairment, and 79 AD dementia patients. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy
48/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD
Key finding: There is limited data on cerebrospinal fluid (CSF) biomarkers in sporadic amyloid-β (Aβ) cerebral amyloid angiopathy (CAA). +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy
53/100 ✓ Peer-reviewed Risk genes beyond APOE Brain : a journal of neurology
Key finding: Cognitive impairment is a frequent comorbidity, but the mechanisms are not fully elucidated. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Detection of Alzheimer Disease Pathology in Patients Using Biochemical Biomarkers: Prospects and Challenges for Use in Clinical Practice
36/100 ✓ Peer-reviewed Down syndrome and Alzheimer's The journal of applied laboratory medicine
Key finding: Thirty-four years ago, amyloid-β 1-42 peptide was identified in amyloid plaques from brain tissue obtained from patients with Alzheimer disease (AD) and Down syndrome. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Fruit and Vegetable Intake and Mental Health in Adults: A Systematic Review
70/100 ✓ Peer-reviewed Risk factors Nutrients
Key finding: The most prominent results indicated that high total intake of fruits and vegetables, and some of their specific subgroups including berries, citrus, and green leafy vegetables, may promote higher levels of optimism and self-efficacy, as well as reduce the level of psychological distress, ambiguity, and cancer fatalism, and protect against depressive symptoms. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Predicting Cognitive Impairment and Dementia: A Machine Learning Approach
49/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: Higher-order factors (e.g., emotional distress, subjective health), which reflect complex interactions between various aspects of an individual, were more important than narrowly defined factors (e.g., clinical and behavioral indicators) when evaluated concurrently to predict cognitive impairment and dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Classification of Alzheimer's Disease with Respect to Physiological Aging with Innovative EEG Biomarkers in a Machine Learning Implementation
48/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: EEG connectivity analysis via a combination of source/connectivity biomarkers, highly correlating with neuropsychological AD diagnosis, could represent a promising tool in identification of AD patients. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting
46/100 ✓ Peer-reviewed Digital health tools The journal of prevention of Alzheimer's disease
Key finding: These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Using Machine Learning to Predict Dementia from Neuropsychiatric Symptom and Neuroimaging Data
56/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: Baseline NPS, categorized for MBI domain and duration, have prognostic utility in addition to brain morphology measures for predicting diagnosis change using ML. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
The Role of Quantitative EEG in the Diagnosis of Neuropsychiatric Disorders
40/100 ✓ Peer-reviewed Digital health tools Journal of medicine and life
Key finding: We conclude that to date, the role of QEEG is not necessarily to pinpoint an immediate diagnosis but to provide additional insight in conjunction with other diagnostic evaluations in order to objective information necessary for obtaining a precise diagnosis, correct disease severity assessment, and specific treatment response evaluation.
Full summary, score breakdown and related studies → Original source
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2020-01-01
Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease
70/100 ✓ Peer-reviewed Digital health tools Brain : a journal of neurology
Key finding: Therefore, we conducted a longitudinal study to examine whether PM2.5 affects the episodic memory decline, and also explored the potential mediating role of increased neuroanatomic risk of Alzheimer's disease associated with exposure. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
The Prevalence of Dementia: A Systematic Review and Meta-Analysis
70/100 ✓ Peer-reviewed How common it is Journal of Alzheimer's disease : JAD
Key finding: Meta-regression was conducted to identify if there were significant differences between groups. +2 more findings
Full summary, score breakdown and related studies → Original source
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