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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,626–14,650 of 27,380 studies, newest first · page 586 of 1096.

November 2017 6

  1. 2017-11-01

    Cognitive Flexibility Training: A Large-Scale Multimodal Adaptive Active-Control Intervention Study in Healthy Older Adults

    ✓ Peer-reviewed Prevention trials Frontiers in human neuroscience

    Key finding: As aging is associated with cognitive decline, particularly in the executive functions, it is essential to effectively improve cognition in older adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-11-01

    Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: Clinical evidence suggests that aberrant tau accumulation in the locus coeruleus and noradrenergic dysfunction may be a critical early step in Alzheimer’s disease progression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-11-01

    How technology is reshaping cognitive assessment: Lessons from the Framingham Heart Study

    ✓ Peer-reviewed Digital health tools Neuropsychology

    Key finding: Technological advances will catalyze groundbreaking discoveries for effective treatments of neurodegenerative cognitive disorders, such as AD, and inform novel strategies for dementia prevention and sustained lifelong cognitive health.

    Full summary, score breakdown and related studies → Original source

  4. 2017-11-01

    Self-rated health and its association with mortality in older adults in China, India and Latin America-a 10/66 Dementia Research Group study

    ✓ Peer-reviewed Disparities Age and ageing

    Key finding: However, in many low- and middle-income countries (LMIC) there is a lack of evaluation and the cross-cultural validity of SRH remains largely untested. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-11-01

    Trends in Dementia Incidence in a Birth Cohort Analysis of the Einstein Aging Study

    ✓ Peer-reviewed Disparities JAMA neurology

    Key finding: Poisson regression was used to model dementia incidence as a function of age, sex, educational level, race, and birth cohort, with profile likelihood used to identify the timing of significant increases or decreases in incidence. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-11-01

    Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Our prospective findings provide evidence for what may be an early contributory role of systemic inflammation in neurodegeneration and cognitive aging. +2 more findings

    Full summary, score breakdown and related studies → Original source

October 2017 19

  1. 2017-10-31

    Insulin Resistance and Alzheimer's Disease: Bioenergetic Linkages

    ✓ Peer-reviewed Risk factors Frontiers in aging neuroscience

    Key finding: Individuals with insulin resistance, type 2 diabetes mellitus (T2D), hyperlipidemia, obesity, or other metabolic disease may have increased risk for the development of AD and similar conditions, such as vascular dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2017-10-31

    The limbic and neocortical contribution of α-synuclein, tau, and amyloid β to disease duration in dementia with Lewy bodies

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In DLB, α-synuclein is an important predictor of disease duration, both independently and synergistically with tau and Aβ. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2017-10-30

    Efficacy and safety of anti-amyloid- β immunotherapy for Alzheimer's disease: a systematic review and network meta-analysis

    ✓ Peer-reviewed Treatments Annals of clinical and translational neurology

    Key finding: For efficacy, in terms of Mini-Mental State Examination, aducanumab and solanezumab are significantly effective than placebo. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-10-30

    TREM2 expression in the human brain: a marker of monocyte recruitment?

    ✓ Peer-reviewed TREM2 and immune genetics Brain pathology (Zurich, Switzerland)

    Key finding: Experimental studies using animal models of AD have highlighted a number of functions associated with TREM2 and its expression by microglial cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-10-29

    Changing the food environment: the effect of trained volunteers on mealtime care for older people in hospital

    ✓ Peer-reviewed Risk factors Proceedings of The Nutrition Society

    Key finding: Poor nutrition among older people in hospital is well recognised in many countries and is associated with poor outcomes of hospital care including increased mortality and longer lengths of stay. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2017-10-28

    Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Previous MRI studies reported cortical iron accumulation in early-onset (EOAD) compared to late-onset (LOAD) Alzheimer disease patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2017-10-27

    Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

    ✓ Peer-reviewed Costs and economics The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

    Key finding: Procedures for pre-analytical sample handling, biobanking, analyses and post-analytical interpretation of the results were intensively studied and optimised. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017-10-27

    Trends in GPCR drug discovery: new agents, targets and indications

    ✓ Peer-reviewed Risk factors Nature reviews. Drug discovery

    Key finding: Here, we report an up-to-date analysis of all GPCR drugs and agents in clinical trials, which reveals current trends across molecule types, drug targets and therapeutic indications, including showing that 475 drugs (~34% of all drugs approved by the US Food and Drug Administration (FDA)) act at 108 unique GPCRs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-10-27

    CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons

    ✓ Peer-reviewed Biomarkers Acta neuropathologica communications

    Key finding: The height of the first action potential at rheobase current injection was also significantly decreased in PSEN2 N141I BFCNs.

    Full summary, score breakdown and related studies → Original source

  10. 2017-10-27

    The experience of psychological distress in family caregivers of people with dementia: A cross-sectional study

    ✓ Peer-reviewed End-of-life care Perspectives in psychiatric care

    Key finding: About half of the caregivers had significant levels of psychological distress. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-10-26

    Age, vascular health, and Alzheimer disease biomarkers in an elderly sample

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Vascular health had quantifiably greater impact on neurodegeneration in AD regions than on amyloid deposition. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2017-10-26

    Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression

    ✓ Peer-reviewed Genetics American journal of human genetics

    Key finding: In this study, we demonstrated RolyPoly's accuracy through simulation and validated previously known tissue-trait associations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-10-25

    Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

    ✓ Peer-reviewed Brain scans and imaging Nature Communications

    It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  14. 2017-10-25

    Comparing clinician descriptions of frailty and geriatric syndromes using electronic health records: a retrospective cohort study

    ✓ Peer-reviewed Health systems and care delivery BMC Geriatrics

    Key finding: Of the 18,341 patients, we found that 2202 (12%) were described as "frail" in clinical notes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2017-10-25

    Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: An increased HV:CTV ratio was predictive of faster clinical decline in participants with AD who were clinically indistinguishable at baseline except for a greater dysexecutive presentation.

    Full summary, score breakdown and related studies → Original source

  16. 2017-10-25

    Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Serum NfL concentration is increased in FAD prior to symptom onset and correlates with measures of disease stage and severity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2017-10-23

    Alzheimer's disease: A matter of blood-brain barrier dysfunction?

    ✓ Peer-reviewed Risk factors The Journal of experimental medicine

    Key finding: An early BBB breakdown and/or dysfunction have been shown in Alzheimer's disease (AD) before dementia, neurodegeneration and/or brain atrophy occur. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2017-10-22

    Dendritic spines provide cognitive resilience against Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: These observations provide cellular evidence to support the hypothesis that dendritic spine plasticity is a mechanism of cognitive resilience that protects older individuals with AD pathology from developing dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2017-10-22

    Leisure time physical activity and dementia risk: a dose-response meta-analysis of prospective studies

    ✓ Peer-reviewed Prevention and risk BMJ open

    Key finding: We have reported, for the first time, the dose-response relationship between LTPA and dementia, further supporting the international PA guideline from the standpoint of dementia prevention.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →