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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,751–12,775 of 27,380 studies, newest first · page 511 of 1096.

June 2019 25

  1. 2019-06-17

    Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology

    ✓ Peer-reviewed Disease mechanisms Molecular neurobiology

    Key finding: Aging, circadian disruption, Aβ accumulation, and tau hyperphosphorylation are the utmost risk factor regarding AD pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-06-17

    Effects of Nilvadipine on Cerebral Blood Flow in Patients With Alzheimer Disease

    ✓ Peer-reviewed Treatments Hypertension (Dallas, Tex. : 1979)

    Key finding: There was no significant change in CBF in the posterior cingulate cortex (Δ=5.2 [95% CI, -16.5 to 27.0] mL/100 g per minute; P=0.63) or other regions of interest. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-06-17

    Effect of a multicomponent exercise programme (VIVIFRAIL) on functional capacity in frail community elders with cognitive decline: study protocol for a randomized multicentre control trial

    ✓ Peer-reviewed Treatments Trials

    Key finding: Moreover, physical activity in the elderly is associated with a decreased risk of mortality, of common chronic illnesses (i.e. cardiovascular disease or osteoarthritis) and of institutionalization as well as with a delay in functional decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-06-14

    The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: Since these two disorders can be concomitant, drawing causal inferences is difficult. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-06-14

    The neuroinflammatory biomarker YKL-40 for neurodegenerative diseases: advances in development

    ✓ Peer-reviewed Disparities Expert review of proteomics

    Key finding: It is not associated with the presence of the APOE -ε4 allele whereas possibly linked to aging, female sex, Hispanic ethnicity and some genetic variants of the chitinase-3-like 1 locus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-06-13

    The neuroprotection of liraglutide on diabetic cognitive deficits is associated with improved hippocampal synapses and inhibited neuronal apoptosis

    ✓ Peer-reviewed Drug development Life sciences

    Key finding: These data suggest that the neuroprotective effects of liraglutide on diabetes-induced cognitive impairments are associated with the improvements of hippocampal synapses and inhibition of neuronal apoptosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2019-06-12

    DPP-4 inhibitor improves learning and memory deficits and AD-like neurodegeneration by modulating the GLP-1 signaling

    ✓ Peer-reviewed Drug development Neuropharmacology

    Key finding: Glucagon-like peptide-1 (GLP-1) signaling in the brain plays an important role in the regulation of glucose metabolism, which is impaired in Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-06-12

    Perspectives and Experiences of Persons With Dementia With Advance Care Planning: An Integrative Literature Review

    ✓ Peer-reviewed End-of-life care Journal of geriatric psychiatry and neurology

    Key finding: Research is needed with methodologically rigorous designs and theoretical frameworks that examine cognitive, psychosocial, and environmental factors influencing ACP attitudes, preferences, and behaviors among PWDs in order to improve engagement among this population. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-06-11

    ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology

    ⚠ Retracted — do not rely on it Vascular contributions PLoS biology

    Key finding: By regulating vascular functions and inflammation in the microvasculature, a disintegrin and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS13) plays a significant protective effect in atherosclerosis and stroke. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-06-11

    α-synuclein in the pathophysiology of Alzheimer's disease

    ✓ Peer-reviewed Risk factors Molecular neurodegeneration

    Key finding: However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn), mainly associated with synucleinopathies like Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), is involved in the pathophysiology of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2019-06-11

    A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The deep-learning time-to-event model predicted individual subjects' progression to AD dementia with a concordance index of 0.762 on 439 Alzheimer's Disease Neuroimaging Initiative testing MCI subjects with follow-up duration from 6 to 78 months (quartiles: [24, 42, 54]) and a concordance index of 0.781 on 40 Australian Imaging Biomarkers and Lifestyle Study of Aging testing MCI subjects with follow-up duration from 18 to 54 months (quartiles: [18, 36, 54]). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2019-06-10

    Education modulates brain maintenance in presymptomatic frontotemporal dementia

    ✓ Peer-reviewed Risk factors Journal of neurology, neurosurgery, and psychiatry

    Key finding: Highly educated at-risk subjects had better cognition and higher grey matter volume at baseline; moreover, higher educational attainment was associated with slower loss of grey matter over time in mutation carriers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2019-06-10

    Genetic analyses of early-onset Alzheimer's disease using next generation sequencing

    ✓ Peer-reviewed Risk genes beyond APOE Scientific reports

    Key finding: This study suggests that individuals diagnosed with AD should be screened for other neurodegenerative disease-associated genes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2019-06-10

    Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Elevated baseline plasma NfL is a prognostic marker of cognitive decline and neuroimaging measures of neurodegeneration, and has similar effect sizes to baseline CSF NfL. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-06-10

    Analytical and clinical performances of the automated Lumipulse cerebrospinal fluid Aβ42 and T-Tau assays for Alzheimer's disease diagnosis

    ✓ Peer-reviewed Tau biomarkers Journal of neurology

    Key finding: Cerebrospinal fluid (CSF) biomarkers are increasingly used to diagnose Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-06-10

    Inflammation and cerebral small vessel disease: A systematic review

    ✓ Peer-reviewed Risk factors Ageing research reviews

    Key finding: Evidence from 82 articles revealed relatively robust associations between SVD and markers of vascular inflammation, especially amongst stroke patients, suggesting that alterations to the endothelium and blood-brain barrier may be a driving force behind SVD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-06-10

    Towards successful digital transformation through co-creation: a longitudinal study of a four-year implementation of digital monitoring technology in residential care for persons with dementia

    ✓ Peer-reviewed Digital health tools BMC health services research

    Key finding: The implementation represented radical innovation and required far more resources than the incremental changes anticipated by the participants. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-06-07

    Moderate- to high-intensity exercise does not modify cortical β-amyloid in Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Alzheimer's & dementia (New York, N. Y.)

    Key finding: The intervention showed no effect on follow-up SUVRs in a covariance analysis with group allocation, baseline intervention SUVR, age, sex, and baseline Mini-Mental State Examination as predictors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2019-06-07

    Chronic Inflammation as an Immunological Abnormality and Effectiveness of Exercise

    ✓ Peer-reviewed Prevention trials Biomolecules

    Key finding: Pro-inflammatory mediators such as cytokines that are secreted in excess from inflammatory cells will not only lead to the development of arteriosclerosis when they chronically affect blood vessels but also bring tissue degeneration and/or dysfunction to various organs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2019-06-07

    Neuroimaging Biomarkers for Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging Molecular neurodegeneration

    Key finding: Numerous advances have been made in developing biomarkers for AD using neuroimaging approaches. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-06-07

    Mediterranean and MIND Diets Containing Olive Biophenols Reduces the Prevalence of Alzheimer's Disease

    ✓ Peer-reviewed Prevention trials International journal of molecular sciences

    Key finding: Higher adherence to the MedDi diet was associated with decreases in cardiovascular and neurological disorders including AD and related cognitive decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-06-06

    Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders

    ✓ Peer-reviewed Genetics American journal of human genetics

    Key finding: Here we have performed genetic linkage analysis and mapped the disease locus to 1p13.3-q23.1; however, whole-exome sequencing revealed no potential disease-causing mutations.

    Full summary, score breakdown and related studies → Original source

  23. 2019-06-06

    Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Previously, we found that familial Parkinson's disease-linked human mutant A53T αS causes aberrant localization of the microtubule-associated protein tau to postsynaptic spines in neurons, leading to postsynaptic deficits. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-06-06

    Analysis of dementia in the US population using Medicare claims: Insights from linked survey and administrative claims data

    ✓ Peer-reviewed Disparities Alzheimer's & dementia (New York, N. Y.)

    Key finding: Survey-based cognitive tests and claims-based dementia diagnosis yielded equal prevalence estimates, yet only half were identified by both measures. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-06-06

    Psychological Interventions for Dementia Caregivers: What We Have Achieved, What We Have Learned

    ✓ Peer-reviewed Caregiving Current psychiatry reports

    Key finding: This article provides a focused review of such methods used in evidence-based intervention programs, along with the mechanisms of change associated with these methods. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →