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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,626–24,650 of 27,380 studies, newest first · page 986 of 1096.

January 2003 21

  1. 2003-01-01

    Neuropathologic changes in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system The Journal of clinical psychiatry

    Key finding: These include alterations in the function of the monoaminergic neural systems that release glutamate, norepinephrine, and serotonin as well as a few neuropeptide-containing systems. +3 more findings

  2. 2003-01-01

    Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology The Journal of neuropsychiatry and clinical neurosciences

    Key finding: The frequency of major depression decreased in severe stages, while agitation, aggression, and psychosis were more frequent in late stages. +3 more findings

  3. 2003-01-01

    Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias

    ✓ Peer-reviewed Cognitive tests and assessment The Journal of neuropsychiatry and clinical neurosciences

    Key finding: The authors used the anxiety subscale of the Neuropsychiatric Inventory (NPI), an instrument with established reliability and validity, to compare patients. +3 more findings

  4. 2003-01-01

    [Biological markers for Alzheimer disease]

    ✓ Peer-reviewed Tau biomarkers Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica

    Key finding: Cerebrospinal fluid (CSF) is a useful source of diagnostic information. +3 more findings

  5. 2003-01-01

    Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development

    ✓ Peer-reviewed Risk genes beyond APOE Neuromolecular medicine

    Key finding: We now provide evidence that AD patients exhibit an enhanced immune response to Abeta and that, contrary to expectations, Abeta antibodies enhance the neurotoxic activity of the peptide. +3 more findings

  6. 2003-01-01

    Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: Given these NRG-1 actions, we hypothesized that the synaptic loss, gliosis, inflammation, and neuronal death occurring in Alzheimer disease (AD) is associated with altered expression of NRG-1 and its receptors (the erbB2, erbB3, and erbB4 membrane tyrosine kinases). +3 more findings

  7. 2003-01-01

    Age-dependent cognitive decline in the APP23 model precedes amyloid deposition

    ✓ Peer-reviewed Risk genes beyond APOE The European journal of neuroscience

    Key finding: A hidden-platform Morris-type water maze showed an age-dependent decline of spatial memory capacities in the APP23 model. +3 more findings

  8. 2003-01-01

    Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down syndrome brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neural transmission. Supplementum

    Key finding: Overexpression of genes located on chromosome 21, as a result of extra gene load, has been considered a central hypothesis for the explanation of the DS phenotype. +1 more finding

  9. 2003-01-01

    Increased light exposure consolidates sleep and strengthens circadian rhythms in severe Alzheimer's disease patients

    ✓ Peer-reviewed Risk factors Behavioral sleep medicine

    Key finding: Sleep in the nursing home environment is extremely fragmented, possibly in part as a result of decreased light exposure. +1 more finding

  10. 2003-01-01

    Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management

    ✓ Peer-reviewed Risk factors Drugs

    Key finding: Management mainly consists of cumulative dose-reduction or lower dose-intensities, especially in patients who are at higher risk to develop neurotoxic side effects.

  11. 2003-01-01

    Nursing home characteristics associated with tube feeding in advanced cognitive impairment

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: Assessment by a speech therapist, staffing ratios, advance directives, fiscal considerations, and specialized dementia units are potentially modifiable factors in nursing homes that may influence the practice of tube feeding in advanced cognitive impairment. +3 more findings

  12. 2003-01-01

    Progressive nonfluent aphasia and subsequent aphasic dementia associated with atypical progressive supranuclear palsy pathology

    ✓ Peer-reviewed Digital health tools European neurology

    Key finding: Neuropathologic examination revealed findings characteristic of progressive supranuclear palsy (PSP) except that the cortical pathology was more widespread than is typical of PSP. +1 more finding

  13. 2003-01-01

    Primary progressive aphasia: PPA and the language network

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: PPA patients showed longer reaction times and reduced accuracy versus controls on the language tasks, but no performance differences on the control task. +1 more finding

  14. 2003-01-01

    Delirium symptoms in post-acute care: prevalent, persistent, and associated with poor functional recovery

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: The data from this study provide strong preliminary evidence that, in patients newly admitted to post-acute care facilities from acute care hospitals, delirium symptoms are prevalent, persistent, and associated with poor functional recovery. +3 more findings

  15. 2003-01-01

    Poor outcome after first-ever stroke: predictors for death, dependency, and recurrent stroke within the first year

    ✓ Peer-reviewed How common it is Stroke

    Key finding: In addition to age and stroke severity, heart diseases and dementia before the stroke seem to have an impact on mortality and recurrence after 1 year. +1 more finding

  16. 2003-01-01

    Mild cognitive impairment: prevalence, prognosis, aetiology, and treatment

    ✓ Peer-reviewed How common it is The Lancet. Neurology

    Key finding: However, recent evidence also suggests that the aetiological heterogeneity among individuals with MCI could be greater than previously reported.

  17. 2003-01-01

    Evaluation of dementia in the cardiovascular health cognition study

    ✓ Peer-reviewed Disparities Neuroepidemiology

    Key finding: The CHS has developed a methodology for longitudinal studies of dementia in large cohorts and represents the largest study of dementia including cognitive testing, MRI and genetic markers.

  18. 2003-01-01

    Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia

    ✓ Peer-reviewed Caregiving The Cochrane database of systematic reviews

    Key finding: Memory problems are a defining feature of the early stages of Alzheimer's disease (AD) and vascular dementia. +1 more finding

  19. 2003-01-01

    Dementia with Lewy bodies

    ✓ Peer-reviewed Brain scans and imaging Seminars in clinical neuropsychiatry

    Key finding: More recently, alpha-synuclein antibodies have revealed extensive neuritic pathology in DLB demonstrating a neurobiological link with other "synucleinopathies" including PD and multiple system atrophy (MSA). +2 more findings

  20. 2003-01-01

    Lecithin for dementia and cognitive impairment

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Alzheimer's disease sufferers have been found to have a lack of the enzyme responsible for converting choline into acetylcholine within the brain. +4 more findings

  21. 2003-01-01

    Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial

    ✓ Peer-reviewed Treatments Clinical therapeutics

    Key finding: The mean (SD) age in the CA group was 72.2(7.5) years (range, 60-80 years), and in the placebo group it was 71.7 (7.4) years(range, 60-80 years). +2 more findings

December 2002 4

  1. 2002-12-28

    Staging of brain pathology related to sporadic Parkinson’s disease

    ✓ Peer-reviewed Brain tissue and pathology Neurobiology of Aging

    Key finding: Lesions initially occur in the dorsal motor nucleus of the glossopharyngeal and vagal nerves and anterior olfactory nucleus. +2 more findings

  2. 2002-12-20

    Lipid rafts: structure, function and role in HIV, Alzheimer's and prion diseases

    ✓ Peer-reviewed Drug development Expert Reviews in Molecular Medicine

    Key finding: Lipid rafts are also preferential sites of formation for pathological forms of the prion protein (PrPSc) and of the [beta]-amyloid peptide associated with Alzheimer's disease.

  3. 2002-12-18

    Role of protein kinase B in Alzheimer's neurofibrillary pathology

    ✓ Peer-reviewed Tau biomarkers Acta neuropathologica

    Key finding: Activated GSK-3 has been previously shown to be preferentially associated with neurofibrillary tangles (NFTs) in Alzheimer's disease (AD) brain. +3 more findings

  4. 2002-12-07

    Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1)

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: We previously found that BACE1 also cleaved a membrane-bound sialyltransferase, ST6Gal I. +3 more findings

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