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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,251–12,275 of 27,380 studies, newest first · page 491 of 1096.

December 2019 15

  1. 2019-12-02

    Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs

    ✓ Peer-reviewed TREM2 and immune genetics Molecular psychiatry

    Key finding: Psychiatric patients may be at higher risk for memory dysfunction and subsequent AD due to the negative effects of stress and depression on the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-12-02

    Identifying undetected dementia in UK primary care patients: a retrospective case-control study comparing machine-learning and standard epidemiological approaches

    ✓ Peer-reviewed Digital health tools BMC medical informatics and decision making

    Key finding: Our model could aid GPs or health service planners with the early detection of dementia.

    Full summary, score breakdown and related studies → Original source

  3. 2019-12-02

    Risks and benefits of unapproved disease-modifying treatments for neurodegenerative disease

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Assignment to active treatment was not beneficial for any of the indications examined and may have been slightly disadvantageous for patients with Alzheimer disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-12-02

    Risks and Benefits of Screening for Dementia in Primary Care: The Indiana University Cognitive Health Outcomes Investigation of the Comparative Effectiveness of Dementia Screening (IU CHOICE)Trial

    ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society

    Key finding: We were unable to detect a difference in HRQOL for screening for ADRD among older adults. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-12-01

    Using Policy to Improve Access to Care for Persons With Alzheimer's Disease

    ✓ Peer-reviewed Costs and economics Journal of gerontological nursing

    Key finding: Due to lack of awareness, health care providers demonstrated <1% use of these assessments in eligible older adults.

    Full summary, score breakdown and related studies → Original source

  6. 2019-12-01

    deepDR: a network-based deep learning approach to in silico drug repositioning

    ✓ Peer-reviewed Drug development Bioinformatics (Oxford, England)

    Key finding: In this study, we developed a network-based deep-learning approach, termed deepDR, for in silico drug repurposing by integrating 10 networks: one drug-disease, one drug-side-effect, one drug-target and seven drug-drug networks. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2019-12-01

    Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

    ✓ Peer-reviewed Genetics Cell

    Key finding: We find that microglia express a conserved core gene program of orthologous genes from rodents to humans, including ligands and receptors associated with interactions between glia and neurons. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-12-01

    A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: We detail cell-type-specific gene expression patterns, unveiling how transcriptional changes in specific cell subpopulations are associated with Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-12-01

    Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Plasma TP42/40 ratio showed a relevant and significant potential as a screening tool to identify brain Aβ positivity in preclinical and prodromal stages of Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-12-01

    Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

    ✓ Peer-reviewed Biomarkers The Lancet. Neurology

    Key finding: Baseline NfL was elevated in symptomatic carriers (median 52 pg/mL [IQR 24-69]) compared with presymptomatic carriers (9 pg/mL [6-13]; p<0·0001) and non-carriers (8 pg/mL [6-11]; p<0·0001), and was higher in converters than in non-converting carriers (19 pg/mL [17-28] vs 8 pg/mL [6-11]; p=0·0007; adjusted for age). +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-12-01

    Advance care planning in different settings for people with dementia: A systematic review and narrative synthesis

    ✓ Peer-reviewed End-of-life care Palliative & supportive care

    Key finding: Future research should focus on ways to involve people with dementia in decision-making through supported means.

    Full summary, score breakdown and related studies → Original source

  12. 2019-12-01

    Hypersynchronization in mild cognitive impairment: the 'X' model

    ✓ Peer-reviewed Disease mechanisms Brain : a journal of neurology

    Key finding: To extract the functional connectivity network with significant changes between both magnetoencephalographic recordings, we evaluated the functional connectivity ratio, defined as functional connectivity post-/pre-condition, in a network-based statistical model with an ANCOVA test with age as covariate. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-12-01

    Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial

    ✓ Peer-reviewed Caregiving JAMA internal medicine

    Key finding: The 780 PWDs (56.3% female; mean [SD] age, 78.1 [9.9] years) and 780 caregivers (70.9% female; mean [SD] age, 64.7 [12.0] years) lived in California (n = 452), Nebraska (n = 284), or Iowa (n = 44). +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2019-12-01

    Efficacy and safety of Shenmayizhi decoction as an adjuvant treatment for vascular dementia: Study protocol for a randomized controlled trial

    ✓ Peer-reviewed Treatments Medicine

    Key finding: This study will provide evidences to evaluate the efficacy and safety of SMYZD in combination with GBEs in treatment of VaD, as well as the adjuvant role of SMYZD in combination. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-12-01

    Associations of dietary choline intake with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study

    ✓ Peer-reviewed Genetics The American journal of clinical nutrition

    Key finding: Higher phosphatidylcholine intake was associated with lower risk of incident dementia and better cognitive performance in men in eastern Finland. +4 more findings

    Full summary, score breakdown and related studies → Original source

November 2019 10

  1. 2019-11-30

    Anti-inflammatory Effect of AZD6244 on Acrolein-Induced Neuroinflammation

    ✓ Peer-reviewed Inflammation and the immune system Molecular neurobiology

    Key finding: Our immunostaining study showed that lipopolysaccharide (LPS, an inflammation inducer as a positive control) increased co-localized immunoreactivities of phosphorylated ERK and ED-1 (a biomarker of activated microglia) in the treated BV-2 cells. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-11-30

    Estimation of Brain Functional Connectivity in Patients with Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging Brain sciences

    Key finding: Our results showed that the two correlation matrices were visually similar but had many differences related to different cognitive functions.

    Full summary, score breakdown and related studies → Original source

  3. 2019-11-30

    Cerebrospinal fluid levels of YKL-40 in prodromal Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Neuroscience letters

    Key finding: The results showed that CSF YKL-40 concentrations were increased in the AD dementia group than in the CN group. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2019-11-30

    The Efficacy of Cognitive Training for Elderly Chinese Individuals with Mild Cognitive Impairment

    ✓ Peer-reviewed Prevention trials BioMed research international

    Key finding: The age of the population is shifting toward the elderly range, which may lead to an increased risk of mild cognitive impairment (MCI). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-11-29

    Transcriptome landscape of myeloid cells in human skin reveals diversity, rare populations and putative DC progenitors

    ✓ Peer-reviewed TREM2 and immune genetics Journal of dermatological science

    Key finding: The heterogeneous functions of dermal myeloid cells in antigen presentation, and scavenging pathogens and cell debris places them centrally in cutaneous inflammation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-11-28

    Peptide-Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

    ✓ Peer-reviewed Treatments Angewandte Chemie (International ed. in English)

    Key finding: Protein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell- and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 diabetes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-11-28

    Amyloid-β-independent regulators of tau pathology in Alzheimer disease

    ✓ Peer-reviewed Genetics Nature reviews. Neuroscience

    Key finding: Genetic data, as well as autopsy and neuroimaging studies in patients with AD, indicate that Aβ plaque deposition precedes cortical tau pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2019-11-28

    Systemic and central nervous system metabolic alterations in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: The observed metabolic alterations were associated with core pathological processes of AD to investigate their relation with amyloid pathology and tau-related neurodegeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-11-28

    From Stroke to Dementia: a Comprehensive Review Exposing Tight Interactions Between Stroke and Amyloid-β Formation

    ✓ Peer-reviewed Disease mechanisms Translational stroke research

    Key finding: Vascular factors predisposing to cerebrovascular disease have also been specifically associated with development of AD, and acute stroke is known to increase the risk to develop dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2019-11-27

    Deep learning to detect Alzheimer's disease from neuroimaging: A systematic literature review

    ✓ Peer-reviewed Digital health tools Computer methods and programs in biomedicine

    Key finding: From a research point of view, impressive results have been reported using computer-aided algorithms, but clinically no practical diagnostic method is available. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →