Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 12,101–12,125 of 27,380 studies, newest first · page 485 of 1096.
January 2020 25
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2020-01-01
Amyloid-β as a Blood Biomarker for Alzheimer's Disease: A Review of Recent Literature
38/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: Alzheimer's disease (AD), the main cause of dementia, is characterized by the aggregation of amyloid-β (Aβ). +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease
60/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: It has been recently associated with acquired brain damage and stroke outcomes. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Blood Amyloid-β Oligomerization as a Biomarker of Alzheimer's Disease: A Blinded Validation Study
43/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: MDS-OAβ to measure plasma Aβ oligomerization is a valuable blood-based biomarker for clinical diagnosis of AD, with high sensitivity and specificity. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals
41/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: These results show that different isoforms of Aβ can be detected in the human retina and moreover support the growing number of studies indicating that AD-related pathological changes occurring in the brain could be reflected in the retina. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer's Disease Pathology
47/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: These results suggest that persons carrying certain genotypes in IL10 (-1082G/A), IL1β (1473C/G), IL6 (-174C/G), and TNFIα (-308A/G) could be more vulnerable to development of neuroinflammation, and consequently of AD. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT
16/100 ⚠ Report — not peer-reviewed End-of-life care Health technology assessment (Winchester, England)
Key finding: Phase 1 (realist review; 86 papers) identified that a key intervention component was the activities enabling the development of moments of connection.
Scored 55 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2020-01-01
Cognitive Impairment Is a Common Comorbidity in Deceased COVID-19 Patients: A Hospital-Based Retrospective Cohort Study
48/100 ✓ Peer-reviewed End-of-life care Journal of Alzheimer's disease : JAD
Key finding: CI is a frequent comorbidity in deceased COVID-19 subjects and is associated with differences in care.
Full summary, score breakdown and related studies → Original source
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2020-01-01
Postoperative delirium is associated with increased plasma neurofilament light
57/100 ✓ Peer-reviewed Clinical safety Brain : a journal of neurology
Key finding: While delirium is associated with cognitive decline and dementia, there is limited evidence to support causality for this relationship. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Clinical Presentation of COVID19 in Dementia Patients
53/100 ✓ Peer-reviewed Clinical safety The journal of nutrition, health & aging
Key finding: The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Advances in Non-Pharmacological Interventions for Subjective Cognitive Decline: A Systematic Review and Meta-Analysis
66/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: Overall, the psychological intervention and cognitive training may be beneficial to cognitive function and psychological well-being. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Circulating Plasma Metabolites and Cognitive Function in a Puerto Rican Cohort
50/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: This untargeted metabolomics study identified potential biomarkers for cognitive function in a cohort of Puerto Rican older adults. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
76/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: The 2-year multidomain FINGER intervention may modulate white matter microstructural alterations. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Impact of 3-Day Combined Anodal Transcranial Direct Current Stimulation-Visuospatial Training on Object-Location Memory in Healthy Older Adults and Patients with Mild Cognitive Impairment
69/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: Cognitive training in MCI may be enhanced by atDCS, but further delineation of the impact of current brain state, as well as temporal characteristics of multi-session atDCS-training application, may be needed to induce longer-lasting effects. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Use of Immersive Virtual Reality in the Assessment and Treatment of Alzheimer's Disease: A Systematic Review
69/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: Nine studies were eligible for inclusion. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Depression is Associated with Tau and Not Amyloid Positron Emission Tomography in Cognitively Normal Adults
47/100 ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD
Key finding: Our results demonstrate that tau, not amyloid, was associated with a depression diagnosis. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020 no date recorded — placed by publication year
Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance
39/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia
Several concepts, which in the aggregate get might be used to account for "resilience" against age- and disease-related changes, have been the subject of much research.
Full summary, score breakdown and related studies → Original source
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2020-01-01
PTI-125 Reduces Biomarkers of Alzheimer's Disease in Patients
55/100 ✓ Peer-reviewed Inflammation and the immune system The journal of prevention of Alzheimer's disease
Key finding: Here we describe results of a Phase 2a study of a promising new drug candidate that significantly reversed all measured biomarkers of Alzheimer's disease, neurodegeneration and neuroinflammation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Neuroimaging in Vascular Cognitive Impairment and Dementia: A Systematic Review
56/100 ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD
Key finding: Numerous criteria for the definition of VaD have been described: the National Institute of Neurological Disorders and Stroke Association Internationale pour Recherche'-et-l'Enseignement en Neurosciences criteria, the State of California Alzheimer's Disease Diagnostic and Treatment Centers criteria, DSM-V criteria, the Diagnostic Criteria for Vascular Cognitive Disorders (a VASCOG Statement), and Vascular Impairment of Cognition Classification Consensus Study. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
51/100 ✓ Peer-reviewed Inflammation and the immune system Neurosciences (Riyadh, Saudi Arabia)
Key finding: Chain-free SFA and TFA occur in greater amounts in the brains of individuals with AD than in those without AD.
Full summary, score breakdown and related studies → Original source
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2020-01-01
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
41/100 ✓ Peer-reviewed Inflammation and the immune system Alzheimer disease and associated disorders
Key finding: Increased levels of inflammatory markers were not associated with faster progression as measured by the annual change on the CDR-SB or MMSE score. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-01-01
Differential role of triggering receptors expressed on myeloid cells 2 R47H in 3 neurodegenerative diseases based on a systematic review and meta-analysis
58/100 ✓ Peer-reviewed TREM2 and immune genetics Medicine
Key finding: The AD set included 23,092 cases and 30,920 controls, the ALS set included 7391 cases and 12,442 controls, and the PD set included 8498 patients and 9161 controls. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial
62/100 ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD
Key finding: Oral benfotiamine is safe and potentially efficacious in improving cognitive outcomes among persons with MCI and mild AD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020 no date recorded — placed by publication year
Relationship between serum TSH level and Alzheimer disease pathology
31/100 ✓ Peer-reviewed Risk factors Alzheimer's & Dementia
Key finding: Serum TSH level is associated with cerebral Aβ burden. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020 no date recorded — placed by publication year
Association between low gait speed and cognition decline in older nursing home residents
31/100 ✓ Peer-reviewed Health systems and care delivery Alzheimer's & Dementia
Key finding: This study founded that low gait speed was significantly associated with dementia in older adults in nursing home. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-01-01
Can exercise affect immune function to increase susceptibility to infection?
47/100 ✓ Peer-reviewed Prevention and risk Exercise immunology review
Key finding: Multiple studies in humans and animals have demonstrated the profound impact that exercise can have on the immune system.
Full summary, score breakdown and related studies → Original source
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