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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,376–12,400 of 27,380 studies, newest first · page 496 of 1096.

October 2019 25

  1. 2019-10-25

    Machine Learning-Based Framework for Differential Diagnosis Between Vascular Dementia and Alzheimer's Disease Using Structural MRI Features

    ✓ Peer-reviewed Digital health tools Frontiers in neurology

    Key finding: The experimental results demonstrate that the SVM with RBF achieved an encouraging performance with sensitivity (SEN), specificity (SPE), and accuracy (ACC) values of 82.65%, 87.17%, and 84.35%, respectively (AUC = 0.861, 95% CI = 0.820-0.902), for the differential diagnosis between VaD and AD. +1 more finding

  2. 2019-10-25

    Tau deposition is associated with functional isolation of the hippocampus in aging

    ✓ Peer-reviewed Brain scans and imaging Nature communications

    Key finding: Functional disconnection between the hippocampus and other components of the MTL memory system, particularly an anterior-temporal network specialized for object memory, is also associated with higher hippocampal ReHo and greater tau burden in anterior-temporal regions. +1 more finding

  3. 2019-10-24

    Microbiota-gut-brain axis and toll-like receptors in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Computational and structural biotechnology journal

    Key finding: Dysbiosis of gut microbiota can induce increased intestinal permeability and systemic inflammation, which may lead to the development of AD pathologies and cognitive impairment via the neural, immune, endocrine, and metabolic pathways. +4 more findings

  4. 2019-10-24

    How Western Diet And Lifestyle Drive The Pandemic Of Obesity And Civilization Diseases

    ✓ Peer-reviewed Prevention trials Diabetes, metabolic syndrome and obesity : targets and therapy

    Key finding: This paper shows that the transition from Paleolithic nutrition to Western diets, along with lack of corresponding genetic adaptations, cause significant distortions of the fine-tuned metabolism that has evolved over millions of years of human evolution in adaptation to Paleolithic diets. +1 more finding

  5. 2019-10-24

    Elements of Palliative Care in the Last 6 Months of Life: Frequency, Predictors, and Timing

    ✓ Peer-reviewed End-of-life care Journal of general internal medicine

    Key finding: Although a high proportion of patients received elements of palliative care, transitions to a goal of comfort or hospice happened very near death. +2 more findings

  6. 2019-10-24

    Effects of computerised cognitive training on cognitive impairment: a meta-analysis

    ✓ Peer-reviewed Prevention trials Journal of neurology

    Key finding: CCT was most effective in cognitive rehabilitation, particularly in the subdomain of memory. +1 more finding

  7. 2019-10-23

    Palliative Care in a Community-Based Serious-Illness Care Program

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: Patients were seen in an 18-month time frame (n = 159). +4 more findings

  8. 2019-10-23

    Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers International review of neurobiology

    Key finding: Multiplex immunoassay conducted on brain lysates showed that alcohol drinking upregulated primary markers of AD pathology in 3xTg-AD mice: Aβ 42/40 ratio in the lateral entorhinal and prefrontal cortex and total Tau expression in the lateral entorhinal cortex, medial prefrontal cortex, and amygdala at 1-month post alcohol exposure. +4 more findings

  9. 2019-10-23

    Dietary salt promotes cognitive impairment through tau phosphorylation

    ✓ Peer-reviewed Prevention and risk Nature

    Key finding: In mice, a salt-rich diet leads to cognitive dysfunction associated with a nitric oxide deficit in cerebral endothelial cells and cerebral hypoperfusion 7 . +2 more findings

  10. 2019-10-23

    Efficacy of Group Reminiscence Therapy on Cognition, Depression, Neuropsychiatric Symptoms, and Activities of Daily Living for Patients With Alzheimer Disease

    ✓ Peer-reviewed Treatments Journal of geriatric psychiatry and neurology

    Key finding: Significant improvements in depressive and neuropsychiatric symptoms were found in the intervention group compared to the control group ( P t = 2.076, P = .041) and 24 weeks follow-up ( t = 3.834, P = .000) compared to controls.

  11. 2019-10-22

    Insomnia in Older Adults

    ✓ Peer-reviewed Risk factors Current geriatrics reports

    Key finding: Insomnia is associated with socioeconomic status, racial and ethnic classification, family relationships, medical and mental health disorders, cognitive function, and dementia. +1 more finding

  12. 2019-10-22

    Cerebrospinal fluid and plasma neurofilament light relate to abnormal cognition

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Plasma NFL was related to all domains (P values ≤ .008) except processing speed (P values ≥ .09). +4 more findings

  13. 2019-10-21

    An audit of dementia education and training in UK health and social care: a comparison with national benchmark standards

    ✓ Peer-reviewed End-of-life care BMC health services research

    Key finding: The development of new and existing training and education should take account of subjects that are currently underrepresented and ensure that training reflects the Training Standard Framework and evidence regarding best practice for delivery. +2 more findings

  14. 2019-10-21

    A Systematic Review of Multimodal Non-Pharmacological Interventions for Cognitive Function in Older People with Dementia in Nursing Homes

    ✓ Peer-reviewed Prevention trials Dementia and geriatric cognitive disorders

    Key finding: Our review suggests that MNPIs may improve the global, executive function and memory of PWD in NHs. +1 more finding

  15. 2019-10-21

    Neurodegenerative Disease Mortality among Former Professional Soccer Players

    ✓ Peer-reviewed How common it is The New England journal of medicine

    Key finding: Over a median of 18 years, 1180 former soccer players (15.4%) and 3807 controls (16.5%) died.

  16. 2019-10-18

    Autophagy and synaptic plasticity: epigenetic regulation

    ✓ Peer-reviewed Disease mechanisms Current opinion in neurobiology

    Key finding: In neurons, autophagy is crucial to proper axon guidance, vesicular release, dendritic spine architecture, spine pruning and synaptic plasticity and, when dysregulated, is associated with brain disorders, including autism spectrum disorders, and neurodegenerative diseases such as Parkinson's and Alzheimer's disease.

  17. 2019-10-18

    High-Throughput Mass Spectrometry Assay for Quantifying β-Amyloid 40 and 42 in Cerebrospinal Fluid

    ✓ Peer-reviewed Biomarkers Clinical chemistry

    Key finding: The assay had a reportable range of 100 to 25000 pg/mL, a limit of quantification of 100 pg/mL, recoveries between 93% and 111%, and intraassay and interassay CV <15% for both peptides. +3 more findings

  18. 2019-10-18

    Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in neuroscience

    Key finding: The pathogenesis of brain impairment caused by chronic hyperglycemia is complex and includes mitochondrial dysfunction, neuroinflammation, neurotransmitters' alteration, and vascular disease, which lead to cognitive impairment, neurodegeneration, loss of synaptic plasticity, brain aging, and dementia. +3 more findings

  19. 2019-10-18

    Predictive Value of 18F-Florbetapir and 18F-FDG PET for Conversion from Mild Cognitive Impairment to Alzheimer Dementia

    ✓ Peer-reviewed Biomarkers Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: On the basis of the independent validation dataset, the 18 F-FDG PET model yielded a significantly higher predictive value than the amyloid PET model. +4 more findings

  20. 2019-10-17

    Adapting Mobile and Wearable Technology to Provide Support and Monitoring in Rehabilitation for Dementia: Feasibility Case Series

    ✓ Peer-reviewed Cognitive tests and assessment JMIR formative research

    Key finding: Smartphones and wearables could provide beneficial and pervasive support and monitoring for rehabilitation among people with dementia. +2 more findings

  21. 2019-10-17

    Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

    ✓ Peer-reviewed Clinical safety Molecular cell

    Key finding: Here we demonstrate that wild-type FUS binds single-stranded RNA stoichiometrically in a length-dependent manner and that multimers induce highly dynamic interactions with RNA, giving rise to small and fluid condensates. +4 more findings

  22. 2019-10-17

    Reformulating Pro-Oxidant Microglia in Neurodegeneration

    ✓ Peer-reviewed TREM2 and immune genetics Journal of clinical medicine

    Key finding: Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered a new subpopulation named disease-associated microglia (DAM). +3 more findings

  23. 2019-10-17
  24. 2019-10-17

    A Comparison of Users and Nonusers of a Web-Based Intervention for Carers of Older Persons With Alzheimer Disease and Related Dementias: Mixed Methods Secondary Analysis

    ✓ Peer-reviewed Treatments Journal of medical Internet research

    Key finding: At baseline, there were no statistically significant differences in demographic characteristics and in outcome variables (HHI, GSES, and SF-12v2 mental component score and physical component score) between users and nonusers. +4 more findings

  25. 2019-10-17

    Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

    ✓ Peer-reviewed Genetics Molecular neurodegeneration

    Key finding: These new knock-in strains offer a novel and dynamic tool to study the role of APOE in AD pathogenesis in a spatially and temporally controlled manner. +1 more finding

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