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Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation
Carol A Derby, Franya Hutchins, Gail A Greendale, Karen A Matthews, Barbara Sternfeld, Susan A Everson-Rose, Rasa Kazlauskaite, Rachel A Whitmer et al.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2021-03-12
Topic: Brain imaging, connectivity and assessment
Diabetes, elevated fasting glucose, central obesity, and heart age greater than chronological age were associated with rate of decline in processing speed during midlife. Vascular risk factors were not related to rate of decline in working or verbal memory. Midlife may be a critical period for intervening on cardiovascular risk factors to prevent or delay later life cognitive impairment and ADRD.
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APA 7th
Derby, C. A., Hutchins, F., Greendale, G. A., Matthews, K. A., Sternfeld, B., Everson-Rose, S. A., et al. (2021). Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1002/alz.12300
Vancouver
Derby CA, Hutchins F, Greendale GA, Matthews KA, Sternfeld B, Everson-Rose SA, et al. Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021. doi:10.1002/alz.12300. PMID: 33710770.
BibTeX
@article{derby2021-33710770,
author = {Derby, Carol A and Hutchins, Franya and Greendale, Gail A and Matthews, Karen A and Sternfeld, Barbara and Everson-Rose, Susan A and Kazlauskaite, Rasa and Whitmer, Rachel A and others},
title = {{Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2021},
doi = {10.1002/alz.12300},
pmid = {33710770},
url = {https://doi.org/10.1002/alz.12300}
}
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Key findings
- Diabetes, elevated fasting glucose, central obesity, and heart age greater than chronological age were associated with rate of decline in processing speed during midlife.
- Vascular risk factors were not related to rate of decline in working or verbal memory.
- Midlife may be a critical period for intervening on cardiovascular risk factors to prevent or delay later life cognitive impairment and ADRD.
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Study details
- Evidence strengthLow
How this study scored 45/100
Published in a leading specialty journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multicenter collaboration and free to read, so those were left out: it earned 25 of the 56 points we could judge it on, which is 45 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2021 — within 6 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multicenter collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 33710770) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 25 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 25 of the 56 points we could judge it on is 45 out of 100. |
| Total | 45 / 100 | — |
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