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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 9,151–9,175 of 27,380 studies, newest first · page 367 of 1096.

February 2022 25

  1. 2022-02-26

    "Aducanumab" making a comeback in Alzheimer's disease: An old wine in a new bottle

    ✓ Peer-reviewed Treatments Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Key finding: The manuscript discusses the failure of anti-amyloid therapies in AD, that have accelerated the need to find a suitable therapeutic approach, followed by the discussion of timeline and impact of aducanumab in AD models, alongside the controversial judgement raising significant question. +1 more finding

  2. 2022-02-25

    Cohort Profile Update: The Study of Health in Pomerania (SHIP)

    ✓ Peer-reviewed Drug development International Journal of Epidemiology

    Key finding: Therefore, respective software was developed in-house.8,9 Segmentation results are then analysed for potential associations with disease risks and to establish reference intervals of organ size and function.10 SHIP is also used as a basis for meta-research with a particular focus on incidental MRI findings and their effects on study participants.11,12 With its large amount of standardized data and the option to internally replicate findings from SHIP-START using data of the independent SHIP-TREND, the project offers good opportunities to apply new bioinformatical tools to mine the data and gain new insights into risk factors and pathomechanisms. +3 more findings

  3. 2022-02-25

    Racial/ethnic disparities in initiation and persistent use of anti-dementia medications

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Outcomes for acetylcholinesterase inhibitor (AChEI) treatment included (1) any new AChEI treatment during follow-up, and (2) persistence of treatment during follow-up categorized into: intermittent treatment (< 50% follow-ups reporting treatment), persistent (≥50% follow-ups), and always treated. +4 more findings

  4. 2022-02-25

    Biofluid-based biomarkers for Alzheimer's disease-related pathologies: An update and synthesis of the literature

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The past few years have seen an explosion in sensitive and specific assays for cerebrospinal fluid (CSF) and blood biomarkers for Alzheimer's disease (AD) and related disorders, as well as some novel assays based on pathological seed-induced protein misfolding in patient samples. +3 more findings

  5. 2022-02-25

    Racial differences in longitudinal Alzheimer's disease biomarkers among cognitively normal adults

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Longitudinal racial differences in amyloid biomarkers are observed.

  6. 2022-02-24

    Alzheimer's Disease Seen through the Eye: Ocular Alterations and Neurodegeneration

    ✓ Peer-reviewed Brain scans and imaging International journal of molecular sciences

    Key finding: There is increasing scientific evidence highlighting the similarities between the eye and other structures of the CNS, suggesting that knowledge acquired in eye research could be useful for research and diagnosis of AD. +2 more findings

  7. 2022-02-24

    Identification of cognitively impaired patients at risk for development of Alzheimer’s disease dementia: an analysis of US Medicare claims data

    ✓ Peer-reviewed Health systems and care delivery Expert Review of Pharmacoeconomics & Outcomes Research

    Key finding: Predictors of an AD dementia diagnosis included age (odds ratio [OR], 1.71) and use of antipsychotics (OR, 2.50) and hypertension medication (OR, 1.25). +4 more findings

  8. 2022-02-24

    Allostatic-Interoceptive Overload in Frontotemporal Dementia

    ✓ Peer-reviewed Digital health tools Biological psychiatry

    Key finding: These results suggest that bvFTD may be characterized by an allostatic-interoceptive overload manifested in ongoing electrophysiological markers, brain atrophy, functional networks, and cognition. +3 more findings

  9. 2022-02-24

    Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The Latino population in the United States is projected to have the steepest increase in Alzheimer's disease (AD) in the next 40 years, compared to other ethnic groups. +1 more finding

  10. 2022-02-23

    National General Health Screening Program in Korea: history, current status, and future direction

    ✓ Peer-reviewed Disparities Precision and Future Medicine

    Key finding: The main target diseases are cerebroand cardiovascular diseases, including hypertension, diabetes mellitus, dyslipidemia, obesity, and related health behaviors. +4 more findings

  11. 2022-02-23

    Association Between Egg Consumption and Dementia Risk in the EPIC-Spain Dementia Cohort

    ✓ Peer-reviewed Prevention and risk Frontiers in nutrition

    Key finding: A total of 774 incident dementia cases were diagnosed and validated, of which 518 were Alzheimer's disease (AD). +4 more findings

  12. 2022-02-23

    Population attributable fraction of modifiable risk factors for dementia in Chile

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The overall weighted PAF for modifiable risk factors was 45.8% (42.2% to 49.3%). +4 more findings

  13. 2022-02-23

    Diabetes: Risk factor and translational therapeutic implications for Alzheimer's disease

    ✓ Peer-reviewed Drug development The European journal of neuroscience

    Key finding: Animal models show that persistent hyperglycaemia results in chronic low-grade inflammation that may contribute to the development of neuroinflammation and accelerate the pathobiology of AD. +2 more findings

  14. 2022-02-23
  15. 2022-02-23

    Plasma biomarkers for Alzheimer's Disease in relation to neuropathology and cognitive change

    ✓ Peer-reviewed Biomarkers Acta neuropathologica

    Key finding: Comparing plasma biomarkers with pathology diagnoses and ratings, we found that P-tau181 (AUC = 0.856) and P-tau231 (AUC = 0.773) showed the strongest overall sensitivity and specificity for AD neuropathological change (ADNC). +1 more finding

  16. 2022-02-23

    Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort Study

    ✓ Peer-reviewed Long-term cohort studies BMJ open

    Key finding: Social isolation and loneliness have been associated with increased risk of dementia, but it is not known whether this risk is modified or confounded by genetic risk of dementia. +3 more findings

  17. 2022-02-23

    Aducanumab Use in Symptomatic Alzheimer Disease Evidence in Focus [RETIRED]: A Report of the AAN Guidelines Subcommittee

    ⚠ Retracted — do not rely on it Drug development Neurology

    Key finding: The author panel systematically reviewed available clinical trial data detailing aducanumab use in individuals with early symptomatic Alzheimer disease. +3 more findings

    Scored 26 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

  18. 2022-02-23

    TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

    ✓ Peer-reviewed Lewy body dementia Nature

    Key finding: Two common intronic UNC13A polymorphisms strongly associated with amyotrophic lateral sclerosis and frontotemporal dementia risk overlap with TDP-43 binding sites. +1 more finding

  19. 2022-02-23

    TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A

    ✓ Peer-reviewed Lewy body dementia Nature

    Key finding: Single nucleotide polymorphisms in UNC13A are among the strongest hits associated with FTD and ALS in human genome-wide association studies 5,6 , but how those variants increase risk for disease is unknown. +1 more finding

  20. 2022-02-23

    Wearable and implantable devices for drug delivery: Applications and challenges

    ✓ Peer-reviewed Digital health tools Biomaterials

    Key finding: Microneedle-skin patches, wound healing patches, drug-eluting contact lenses, mouth guards, intra-vaginal rings, pharmaceutical jewelry, and drug-loaded self-care textiles are popular WDs explored in drug delivery. +4 more findings

  21. 2022-02-23

    Associations of Stages of Objective Memory Impairment With Amyloid PET and Structural MRI: The A4 Study

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Participants had a mean age of 71.3 (SD 4.6) years; 40.6% were male; and 34.6% were APOE ε4 positive. +3 more findings

  22. 2022-02-22

    Social Isolation and Nursing Leadership in Long-Term Care: Moving Forward After COVID-19

    ✓ Peer-reviewed Risk factors The Nursing clinics of North America

    Key finding: Nursing leaders have a responsibility to promote and facilitate social engagement and connectedness to mitigate social isolation in long-term care (LTC). +4 more findings

  23. 2022-02-22
  24. 2022-02-22

    The pathogenic effects of particulate matter on neurodegeneration: a review

    ✓ Peer-reviewed Risk factors Journal of biomedical science

    Key finding: Epidemiological studies involving data from millions of patients or volunteers have associated PM with increased risk of dementia and Alzheimer's disease in the elderly and cognitive dysfunction and neurodegenerative pathology across all age groups, suggesting that PM may be a risk factor for neurodegenerative diseases. +1 more finding

  25. 2022-02-22

    The Impact of COVID-19 Confinement on Cognition and Mental Health and Technology Use Among Socially Vulnerable Older People: Retrospective Cohort Study

    ✓ Peer-reviewed Cognitive tests and assessment Journal of medical Internet research

    Key finding: Our findings show that the first months of the outbreak did not significantly impact the cognition, quality of life, perceived health status, and depression of our study population when making comparisons with baseline assessments prior to the outbreak. +4 more findings

Browse the library by subject, with the full score breakdown →