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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 4,151–4,175 of 27,380 studies, newest first · page 167 of 1096.

June 2025 12

  1. 2025-06-01

    Cognitive Stability Among Plasma p-tau 181 Negative Individuals: A 5-year Analysis of the Multidomain Alzheimer Prevention Trial Study

    ✓ Peer-reviewed Tau biomarkers The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: This study aims to assess the evolution of cognitive performances over a 5-year follow-up period in community-dwelling older people with negative plasma p-tau181 levels and to determine whether frailty could discriminate between those who experience cognitive decline and those who do not, in the p-tau negative groups. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-06-01

    Associations between objective sleep metrics and brain structure in cognitively unimpaired adults: interactions with sex and Alzheimer's biomarkers

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Poor subjective sleep quality is linked to reduced brain volume and cortical thickness (CTh), but associations with objective sleep measures, particularly regarding sex and AD pathology, remain unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-06-01

    Cerebrospinal Fluid Biomarkers for Alzheimer Disease Among Patients With Dementia

    ✓ Peer-reviewed Tau biomarkers JAMA neurology

    Key finding: The defining pathological features of Alzheimer disease (AD) may also be contributing factors in other dementias. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2025-06-01

    Lipoprotein(a) levels in Down syndrome: A conundrum

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Adults with DS may have unique neuro- and cardio- protective factors that deserve future investigation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-06-01

    Alpha-synuclein co-pathology in Down syndrome-associated Alzheimer's disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These findings highlight LBP prevalence in DSAD but suggest current SAA may fail to detect limited αSyn deposition. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-06-01

    The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer's disease in Down syndrome: A decade of discovery

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Over 10 years, > 10000 clinical visits were conducted; follow-up showed that progression to symptomatic AD before age 40 was rare, but rates increased after age 50 (> 50% within 5 years). +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2025-06-01

    Modulation of Cortical and Hippocampal Functional MRI Connectivity Following Transcranial Alternating Current Stimulation in Mild Alzheimer Disease

    ✓ Peer-reviewed Treatments Radiology

    Key finding: Cognitive performance in mild AD improved following tACS, with increased FC within cortical networks and between the hippocampus and specific cortical regions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2025-06-01

    Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This approach offers a sensitive method for identifying individuals at high risk for AD-related cognitive decline.

    Full summary, score breakdown and related studies → Original source

  9. 2025-06 month only

    Diagnostic performance of plasma p-tau217 and Aβ42/40 biomarkers in the outpatient memory clinic

    ✓ Peer-reviewed Biomarkers Alzheimer's & Dementia

    Key finding: Plasma p-tau217 and p-tau217/Aβ42 concentrations demonstrated robust diagnostic performance in a heterogeneous clinical cohort; interpretation requires consideration of kidney function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-06 month only

    Diagnostic performance of plasma Aβ42/40 ratio, p-tau181, GFAP, and NfL along the continuum of Alzheimer's disease and non-AD dementias: An international multi-center study

    ✓ Peer-reviewed Biomarkers Alzheimer's & Dementia

    Key finding: Plasma phosphorylated tau (p-tau)181, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and amyloid beta ratio (Aβ42/40) may have diagnostic and prognostic value in Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2025-06 month only

    Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways

    ✓ Peer-reviewed Genetics Alzheimer's & Dementia

    Key finding: EOAD, although sharing genes with LOAD, harbors unique genes and pathways that could be used to create better prediction models or target identification. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2025-06-01

    Risk of Dementia in Individuals With Emergency Department Visits or Hospitalizations Due to Cannabis

    ✓ Peer-reviewed Prevention and risk JAMA Neurology

    Key finding: Individuals with cannabis use severe enough to require hospital-based care were at increased risk of a new dementia diagnosis compared with those with all-cause hospital-based care or the general population. +4 more findings

    Full summary, score breakdown and related studies → Original source

May 2025 13

  1. 2025-05-31

    Altered Hepatic Metabolism in Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Cell reports

    Key finding: Bulk RNA-sequencing revealed widespread impacts of the Dp16 model on hepatic metabolism and inflammation, while single-cell transcriptomics highlighted cell types associated with these observations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2025-05-31

    Impact of disease type and temporal trends on the proximity of palliative care initiation to death in older adults: a population-based study

    ✓ Peer-reviewed End-of-life care Age and Ageing

    Key finding: Among 177 403 decedents, 82.41% had cancer and 17.59% non-cancer diagnoses. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-05-31

    Medications associated with dizziness or hypotension and adverse outcomes: an electronic health record study in older adults with dementia

    ✓ Peer-reviewed Clinical safety Age and Ageing

    Key finding: Of the patients, 82.2% were receiving at least one dizziness-associated medication and 71.2% at least one hypotension-associated medication. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2025-05-31

    Validation of the 4AT for assessing recovery from delirium in older hospital patients

    ✓ Peer-reviewed Clinical safety Age and Ageing

    Key finding: A total of 120 people with delirium participated [median age 86.3, range 70-99, 67 (55.8%) female and 55 (45.8%) with dementia]. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-05-31

    End-of-life dementia care: a qualitative study of the experiences and perceptions of minority ethnic and economically disadvantaged groups

    ✓ Peer-reviewed Disparities Age and Ageing

    Key finding: Data point to cultural, socioeconomic and systemic barriers to accessing quality EOL care for PLWD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-05-31

    Current and Future Replacement and Opportunity Costs of Family Caregiving for Older Americans With and Without Dementia

    ✓ Peer-reviewed Costs and economics Innovation in Aging

    Key finding: Current annual replacement cost of unpaid family care is between $96 and $182 billion, 44% of which is accounted for by dementia caregiving.

    Full summary, score breakdown and related studies → Original source

  7. 2025-05-31

    Sativex (nabiximols) for the treatment of Agitation & Aggression in Alzheimer's dementia in UK nursing homes: a randomised, double-blind, placebo-controlled feasibility trial

    ✓ Peer-reviewed Clinical trials Age and Ageing

    Key finding: Between October 2021 and June 2022, 53 candidates were assessed; 29 met eligibility criteria and were randomised. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2025-05-30

    Compositional and functional gut microbiota alterations in mild cognitive impairment: links to Alzheimer's disease pathology

    ✓ Peer-reviewed Disease mechanisms Alzheimer's research & therapy

    Key finding: We identified 59 key microbial species linked to MCI and AD biomarkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-05-30

    Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species

    ✓ Peer-reviewed Treatments Journal of translational medicine

    Key finding: DO11.10 cells expressing E2814-CAR-but not Lec-CAR-responded to tau PFFs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-05-30

    Brain MRI signatures across sex and CSF Alzheimer's disease biomarkers

    ✓ Peer-reviewed Tau biomarkers Brain communications

    Key finding: Second, we examined volumetric associations with amyloid (amyloid positive, tau negative versus control) and tau in the presence of amyloid (amyloid positive, tau positive versus amyloid positive, tau negative) across 52 brain areas. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2025-05-30

    Blood essential trace elements and Alzheimer's disease biomarkers in midlife

    ✓ Peer-reviewed Biomarkers Frontiers in aging neuroscience

    Key finding: In the multivariable linear regression models, a doubling of serum molybdenum level was associated with 9.4% higher Aβ42/40 ratio (95% CI: 0.8, 18.6%; p = 0.03), and a doubling of serum cobalt level with 17.5% higher p-tau181 level (95% CI: 3.1, 33.8%; p = 0.02). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-05-30

    Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

    ✓ Peer-reviewed Treatments Frontiers in pharmacology

    Key finding: Four signal calculation methods were used to assess potential adverse reaction signals of lecanemab and aducanumab. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2025-05-30

    A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

    ✓ Peer-reviewed Prevention trials Journal of the Chinese Medical Association

    Key finding: Over the past decades, significant advances in diagnostic biomarkers and disease-modifying therapies have reshaped the treatment landscape.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →