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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,651–10,675 of 27,380 studies, newest first · page 427 of 1096.

January 2021 25

  1. 2021-01-18

    Circadian and Sleep Dysfunctions in Neurodegenerative Disorders-An Update

    ✓ Peer-reviewed Risk factors Frontiers in neuroscience

    Key finding: Recent evidence suggests that sleep and circadian disturbances may influence the neurodegenerative processes as well as be their consequence.

    Full summary, score breakdown and related studies → Original source

  2. 2021-01-18

    Facing the digital divide into a dementia clinic during COVID-19 pandemic: caregiver age matters

    ✓ Peer-reviewed Digital health tools Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    Key finding: The most impacting factors on digital divide in our population are the social support networks and the experience with the technology: the presence of a digital native caregiver. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-01-17

    A Transfer Learning Approach for Early Diagnosis of Alzheimer's Disease on MRI Images

    ✓ Peer-reviewed Long-term cohort studies Neuroscience

    Key finding: Deep learning architecture produces impressive results in such research. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-01-16

    Crosstalk between Depression and Dementia with Resting-State fMRI Studies and Its Relationship with Cognitive Functioning

    ✓ Peer-reviewed Risk factors Biomedicines

    Key finding: Advances in neuroimaging, including resting-state functional MRI (fMRI), have been used to address neural systems that contribute to clinical symptoms and functional changes across various psychiatric disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-01-16

    RETRACTED: Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer's Disease

    ⚠ Retracted — do not rely on it Drug development International journal of molecular sciences

    Key finding: The extent of neurodegeneration, Aβ plaque load, and key proteins associated with the insulin signaling pathways were measured using Western blot and neuroinflammation (via immunohistological assays) in the cortical and hippocampal regions of the brain were assessed following a series of behavioral tests used to measure cognitive function after LIR or vehicle treatments. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-01-15

    Molecular imaging of beta-amyloid deposition in late-life depression

    ✓ Peer-reviewed Risk factors Neurobiology of aging

    Key finding: Late-life depression (LLD) is associated with an increased risk of all-cause dementia and may involve Alzheimer's disease pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2021-01-15

    Past, present and future role of retinal imaging in neurodegenerative disease

    ✓ Peer-reviewed Brain scans and imaging Progress in retinal and eye research

    Key finding: Technologies such as optical coherence tomography have dramatically changed our understanding of retinal disease and in many cases have significantly improved their clinical management. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-01-15

    The perspectives of people with dementia on their future, end of life and on being cared for by others: A qualitative study

    ✓ Peer-reviewed Health systems and care delivery Journal of Clinical Nursing

    Key finding: Five overarching themes derived from the interviews were as follows: (a) My life still has value and meaning, (b) I am my own unique individual, (c) I place my trust in other people, (d) The future worries me, and (e) I accept and embrace what life brings. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-01-15

    TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ42 in HMC3 cells

    ✓ Peer-reviewed TREM2 and immune genetics Molecular immunology

    Key finding: Also present are dystrophic neurites, loss of synapses, neuronal death, and gliosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-01-14

    Matching Clinical Diagnosis and Amyloid Biomarkers in Alzheimer's Disease and Frontotemporal Dementia

    ✓ Peer-reviewed Brain scans and imaging Journal of personalized medicine

    Key finding: Amyloid-PET presented higher diagnostic accuracy, sensitivity, and NPV than CSF Aβ1-42 but not Aβ42/40 ratio. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-01-14

    Altered Gut Microbial Metabolites in Amnestic Mild Cognitive Impairment and Alzheimer's Disease: Signals in Host-Microbe Interplay

    ✓ Peer-reviewed Mild cognitive impairment Nutrients

    Key finding: With the use of liquid-chromatography/gas chromatography mass spectrometry metabolomics profiling, we identified significant differences between AD and HC for tryptophan metabolites, short-chain fatty acids (SCFAs), and lithocholic acid, the majority of which correlated with altered microbiota and cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2021-01-14

    Impact of Combined Photo-Biomodulation and Aerobic Exercise on Cognitive Function and Quality-of-Life in Elderly Alzheimer Patients with Anemia: A Randomized Clinical Trial

    ✓ Peer-reviewed Treatments International journal of general medicine

    Key finding: Clinical trial registration www.

    Full summary, score breakdown and related studies → Original source

  13. 2021-01-13

    Problem-focused coping underlying lower caregiver burden in ALS-FTD: implications for caregiver intervention

    ✓ Peer-reviewed Caregiving Amyotrophic lateral sclerosis & frontotemporal degeneration

    Key finding: High-burden caregivers were more likely to be caring for patients with a diagnosis of ALS-FTD (p =.0001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-01-13

    Non-genetic risk and protective factors and biomarkers for neurological disorders: a meta-umbrella systematic review of umbrella reviews

    ✓ Peer-reviewed Prevention trials BMC medicine

    Key finding: The search yielded 115 distinctly named non-genetic risk and protective factors with a significant association, with various strengths of evidence. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-01-12

    Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis

    ✓ Peer-reviewed Risk genes beyond APOE Cell reports

    Key finding: Altogether, these results support altered neurogenesis as a result of fAD mutations and suggest that neural stem cell biology is affected in aging and disease.

    Full summary, score breakdown and related studies → Original source

  16. 2021-01-12

    Identification of Cathepsin D as a Plasma Biomarker for Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Cells

    Key finding: By analyzing quantitative immunoblot and ELISA, we found that the plasma level of cathepsin D, a major lysosomal protease, was decreased in the group with amyloid plaque deposition at the brain compared to the control group. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2021-01-12

    Familial Alzheimer's disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues

    ✓ Peer-reviewed Biomarkers The Journal of biological chemistry

    Key finding: Mutations in the transmembrane domain of amyloid β-protein precursor (APP) associated with early-onset familial Alzheimer's disease (FAD) can alter the ratio of aggregation-prone 42-residue Aβ (Aβ42) to 40-residue Aβ (Aβ40). +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2021-01-12

    An MRI-based strategy for differentiation of frontotemporal dementia and Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's research & therapy

    Key finding: The differential diagnosis of frontotemporal dementia (FTD) and Alzheimer's disease (AD) is difficult due to the overlaps of clinical symptoms. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-01-12

    Mind the gap: from neurons to networks to outcomes in multiple sclerosis

    ✓ Peer-reviewed Brain scans and imaging Nature reviews. Neurology

    Key finding: The results of initial longitudinal studies suggest that these changes evolve rather than simply increase over time and are linked with clinical features.

    Full summary, score breakdown and related studies → Original source

  20. 2021-01-11

    Molecular characterization of selectively vulnerable neurons in Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Alzheimer's disease (AD) is characterized by the selective vulnerability of specific neuronal populations, the molecular signatures of which are largely unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021-01-11

    Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Translational psychiatry

    Key finding: Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in blood samples, and has been associated with Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-01-11

    FUS and TDP-43 Phases in Health and Disease

    ✓ Peer-reviewed Lewy body dementia Trends in biochemical sciences

    Key finding: The distinct prion-like domains (PrLDs) of FUS and TDP-43, modulate phase transitions that result in condensates with a range of material states.

    Full summary, score breakdown and related studies → Original source

  23. 2021-01-11

    Evaluation of Wearable Technology in Dementia: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Digital health tools Frontiers in medicine

    Key finding: Forty-eight studies from 18,456 screened abstracts (Dementia: n = 2,516, Control: n = 1,224) met inclusion criteria for the systematic review. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-01-10

    How can dementia and disability be prevented in older adults: where are we today and where are we going?

    ✓ Peer-reviewed Prevention and risk Journal of internal medicine

    Key finding: Dementia and physical disability are closely linked with shared risk factors and possible shared underlying mechanisms supporting the possibility of integrated preventive interventions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-01-09

    Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline

    ✓ Peer-reviewed Prevention trials Contemporary clinical trials

    Key finding: Alzheimer's dementia (AD) is the sixth leading cause of death in the U.S., with an estimated $305 billion cost of care in 2020.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →