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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,326–10,350 of 27,380 studies, newest first · page 414 of 1096.

April 2021 25

  1. 2021-04-09

    Blood biomarkers for dementia in Hispanic and non-Hispanic White adults

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (New York, N. Y.)

    Key finding: T-tau, NfL, GFAP, and YKL-40 discriminated between diagnostic groups (receiver operating curve: 0.647-0.873). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-04-09

    Bidirectional Mapping of Brain MRI and PET With 3D Reversible GAN for the Diagnosis of Alzheimer's Disease

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: Discarding samples without PET data is a common method in previous studies, but the reduction in the number of samples will result in a decrease in model performance. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-04-09

    Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis

    ✓ Peer-reviewed Disease mechanisms Brain, behavior, and immunity

    Key finding: Here, we found that an 8-week treatment of MOS (0.12%, w/v in the drinking water) significantly improved cognitive function and spatial memory, accompanied by attenuated the anxiety- and obsessive-like behaviors in the 5xFAD transgenic AD mice model. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-04-09

    A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: Aducanumab is an anti-amyloid-β (Aβ) antibody that achieved reduced amyloid pathology in Alzheimer's disease (AD) trials; however, it is controversial whether it also improved cognition, which has been suggested would require a sufficiently high cumulative dose of the antibody in the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-04-08

    Tau strains shape disease

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Data from multiple laboratories now suggest that tau acts as a prion. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2021-04-07

    Dual Sensory Impairment and Cognitive Impairment in the Korean Longitudinal Elderly Cohort

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: At baseline, DSI was significantly associated with increased dementia prevalence compared to normal sensory function (odds ratio [OR] 2.17, 95% confidence interval [CI] 1.17-4.02), but SSI was not (OR 1.27, 95% CI 0.66-2.41). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-04-07

    Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

    ✓ Peer-reviewed Genetics Neuron

    Key finding: Single-nucleus RNA sequencing analysis revealed striking gene expression changes in all cell types, with astrocytic APOE4 removal decreasing disease-associated gene signatures in neurons, oligodendrocytes, astrocytes, and microglia.

    Full summary, score breakdown and related studies → Original source

  8. 2021-04-07

    Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: We tested the hypothesis that plasma neurofilament light chain (NfL) identifies asymptomatic carriers of familial frontotemporal lobar degeneration (FTLD)-causing mutations at risk of disease progression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-04-06

    Differences in Burden Severity in Adult-Child Family Caregivers and Spousal Caregivers of Persons with Dementia

    ✓ Peer-reviewed Caregiving Journal of gerontological social work

    Key finding: Researchers are continuing to focus on the nature and sources of burden of family caregivers of persons living with dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-04-06

    TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: The central role of the resident innate immune cells of the brain (microglia) in neurodegeneration has become clear over the past few years largely through genome-wide association studies (GWAS), and has rapidly become an active area of research. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-04-06

    Use of antipsychotics in Denmark 1997-2018: a nation-wide drug utilisation study with focus on off-label use and associated diagnoses

    ✓ Peer-reviewed End-of-life care Epidemiology and psychiatric sciences

    Key finding: We aimed to explore diagnoses associated with antipsychotic use, treatment patterns and characteristics of users without diagnoses relevant to antipsychotic treatment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-04-06

    6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

    ✓ Peer-reviewed Getting a diagnosis The lancet. Psychiatry

    Key finding: As with incidences, HRs were higher in patients who had more severe COVID-19 (eg, those admitted to ITU compared with those who were not: 1·58, 1·50-1·67, for any diagnosis; 2·87, 2·45-3·35, for any first diagnosis). +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-04-05

    Effects of monoclonal antibodies against amyloid-β on clinical and biomarker outcomes and adverse event risks: A systematic review and meta-analysis of phase III RCTs in Alzheimer's disease

    ✓ Peer-reviewed Treatments Ageing research reviews

    Key finding: In this meta-analysis of phase III trials in AD, we found that monoclonal antibodies against Aβ induced clinical improvements of small effect sizes, biomarker improvements of large effect sizes, and increases in risk for the hallmark adverse event, ARIA, by a large effect size, when all drugs were pooled together. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-04-03

    Educational Benefits and Cognitive Health Life Expectancies: Racial/Ethnic, Nativity, and Gender Disparities

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: White respondents lived a greater percentage of their remaining lives cognitively healthy than their minority Black or Hispanic counterparts, regardless of level of education. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-04-03

    Function-Focused Person-Environment Fit for Long-Term Care Residents With Dementia: Impact on Apathy

    ✓ Peer-reviewed Health systems and care delivery The Gerontologist

    Key finding: Yet, the association became not significant after controlling for individual physical function. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-04-03

    Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In non-demented individuals along the AD continuum, p-tau drives cognitive dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2021-04-03

    Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Genome-wide association studies have led to numerous genetic loci associated with Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  18. 2021-04-01

    Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Cells

    Key finding: Recent studies suggested that gut microbiota can influence AD progression; however, potential mechanisms linking the gut microbiota with AD pathogenesis remain obscure. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-04-01

    Comparison of dementia risk after age 50 between individuals with and without HIV infection

    ✓ Peer-reviewed Digital health tools AIDS (London, England)

    Key finding: Compared with PWOH, PWH were at 58% higher risk for dementia despite HIV treatment with ART. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2021-04-01

    Age-Related Hearing Loss, Late-Life Depression, and Risk for Incident Dementia in Older Adults

    ✓ Peer-reviewed Risk factors The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Both HL and depression are independent risk factors for eventual conversion to dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-04-01

    Current advances in plasma and cerebrospinal fluid biomarkers in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Current opinion in neurology

    Key finding: This review provides a concise overview of recent advances in cerebrospinal fluid (CSF) and blood-based biomarkers of Alzheimer's disease lesions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-04-01

    Identifying the Distinct Cognitive Phenotypes in Multiple Sclerosis

    ✓ Peer-reviewed Hippocampus size on brain scans JAMA neurology

    Key finding: Patients with preserved cognition and mild-verbal memory/semantic fluency were younger (mean [SD] age, 36.5 [9.8] years and 38.2 [11.1] years) and had shorter disease duration (mean [SD] 8.0 [7.3] years and 8.3 [7.6] years) compared with patients with mild-multidomain (mean [SD] age, 42.6 [11.2] years; mean [SD] disease duration, 12.8 [9.6] years; P < .001), severe-executive/attention (mean [SD] age, 42.9 [11.7] years; mean [SD] disease duration, 12.2 [9.5] years; P < .001), and severe-multidomain (mean [SD] age, 44.0 [11.0] years; mean [SD] disease duration, 13.3 [10.2] years; P < .001) phenotypes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-04-01

    Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries: A Systematic Review

    ✓ Peer-reviewed Risk genes beyond APOE Alzheimer disease and associated disorders

    Key finding: There is a dearth of studies on the genetics of AD in the Arab world. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-04-01

    ISEE Young Virtual Conference, Basel, Switzerland, 18-19 February, 2021

    ✓ Peer-reviewed Risk factors Environmental Epidemiology

    Key finding: BC residual was significantly associated with worse cognitive performance. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-04-01

    The development and convergence of co-pathologies in Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Brain : a journal of neurology

    Key finding: To investigate how plaques, tangles, age and apolipoprotein E ε4 (APOE ε4) interact with co-pathologies in Alzheimer's disease, we analysed 522 participants ≥50 years of age with and without dementia from the Center for Neurodegenerative Disease Research (CNDR) autopsy program and 1340 participants in the National Alzheimer's Coordinating Center (NACC) database. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →