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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,201–10,225 of 27,380 studies, newest first · page 409 of 1096.

May 2021 25

  1. 2021-05-19

    Fungally Derived Isoquinoline Demonstrates Inducer-Specific Tau Aggregation Inhibition

    ✓ Peer-reviewed Drug development Biochemistry

    Key finding: Recent structural studies have shown that the tau filaments isolated from different neurodegenerative disorders have structurally distinct fibril cores that are specific to the disease. +2 more findings

  2. 2021-05-19

    Novel Alzheimer's disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

    ✓ Peer-reviewed Genetics Translational psychiatry

    Key finding: Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with a complex genetic etiology. +2 more findings

  3. 2021-05-19

    Geographic disparities in mortality from Alzheimer's disease and related dementias

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: The county clusters with the highest and lowest AD mortality rates were in Washington (WA) and New York (NY), respectively, with other notable high-mortality clusters on the border of Tennessee, Georgia, and Alabama as well as in North Dakota and South Dakota. +4 more findings

  4. 2021-05-19

    Sex differences in the association between major cardiovascular risk factors in midlife and dementia: a cohort study using data from the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies BMC medicine

    Key finding: Sex differences in major cardiovascular risk factors for incident (fatal or non-fatal) all-cause dementia were assessed in the UK Biobank. +3 more findings

  5. 2021-05-18

    Hearing Impairment and Cognition in an Aging World

    ✓ Peer-reviewed Risk factors Journal of the Association for Research in Otolaryngology : JARO

    Key finding: With the increasing number of older adults around the world, the overall number of dementia cases is expected to rise dramatically in the next 40 years. +2 more findings

  6. 2021-05-18

    Altered Functional Connectivity of Hippocampal Subfields in Poststroke Dementia

    ✓ Peer-reviewed Brain scans and imaging Journal of magnetic resonance imaging : JMRI

    Key finding: Our results showed HP was functionally divided into HPhead , HPbody , and HPtail bilaterally along the longitudinal axis. +4 more findings

  7. 2021-05-18

    P-tau/Aβ42 and Aβ42/40 ratios in CSF are equally predictive of amyloid PET status

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: These data suggest that p-tau/Aβ42 and Aβ42/40 ratios provide similar clinical information in the assessment of amyloid pathology. +3 more findings

  8. 2021-05-18
  9. 2021-05-17

    Tau-Targeted Multifunctional Nanoinhibitor for Alzheimer's Disease

    ✓ Peer-reviewed Drug development ACS applied materials & interfaces

    Key finding: The aggregation of tau exerts neurotoxicity, and its spreading in the brain is associated with increasing severity of clinical symptoms for AD patients; thus tau-targeting therapies hold great potential against AD.

  10. 2021-05-17

    Ocular biomarkers and their role in the early diagnosis of neurocognitive disorders

    ✓ Peer-reviewed Brain scans and imaging European journal of ophthalmology

    Key finding: Since the introduction of the non-invasive optical coherence tomography (OCT) and the newly developed modality OCT-angiography (OCT-A) that can demonstrate the structure and the microvasculature of the retina and choroid, respectively, there have been promising results regarding the value of the ophthalmologic examination in the early diagnosis of Alzheimer's disease.

  11. 2021-05-17

    The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis

    ✓ Peer-reviewed Biomarkers Clinica chimica acta; international journal of clinical chemistry

    Key finding: The PrecivityAD™ assays are precise, accurate, sensitive, and linear over a wide analytical range, free from significant interferences, and suitable for use in the clinical laboratory. +2 more findings

  12. 2021-05-16

    Virtual Reality-Based Cognitive Stimulation on People with Mild to Moderate Dementia due to Alzheimer's Disease: A Pilot Randomized Controlled Trial

    ✓ Peer-reviewed Cognitive tests and assessment International journal of environmental research and public health

    Key finding: However, the results of such an approach on dementia caused by Alzheimer's disease (AD) are still lacking. +1 more finding

  13. 2021-05-14

    Dementia Incidence, Burden and Cost of Care: A Filipino Community-Based Study

    ✓ Peer-reviewed Costs and economics Frontiers in public health

    Key finding: The crude incidence rate was 16 (CI: 13-20) cases per 1,000 person-years (pyr) with 17 (CI: 12-21) per 1,000 pyr for females and 14 (CI: 9-21) per 1,000 pyr for males. +4 more findings

  14. 2021-05-14

    TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We identify novel genome-wide significant associations between DNA variants in TMEM106B and CSF levels of NfL, and between CPOX and YKL-40. +3 more findings

  15. 2021-05-14

    MIND diet and cognitive performance in older adults: a systematic review

    ✓ Peer-reviewed Prevention trials Critical reviews in food science and nutrition

    Key finding: All of the included studies indicated that adherence to the MIND diet was positively associated with specific domains, but not all, of cognition and global cognitive function (78% of the studies) in older adults. +1 more finding

  16. 2021-05-14

    Dying with dementia in Medicare Advantage, Accountable Care Organizations, or traditional Medicare

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: Among 370,094 persons with dementia, 93,801 (25.4%) were in MA (mean age [SD], 86.9 [7.7], 67.6% female), 39,586 (10.7%) were ACO attributed (mean age [SD], 87.2 [7.6], 67.3% female), and 236,707 (63.9%) were in TM (mean age [SD], 87.0 [7.8], 67.6% female). +4 more findings

  17. 2021-05-14

    Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk

    ✓ Peer-reviewed Brain tissue and pathology Nature aging

    Key finding: We quantified 4,877 plasma proteins in nondemented older adults in the Atherosclerosis Risk in Communities cohort and performed a proteome-wide association study of dementia risk over five years (n = 4,110; 428 incident cases). +3 more findings

  18. 2021-05-14

    Anticholinergic Medication Burden-Associated Cognitive Impairment in Schizophrenia

    ✓ Peer-reviewed Caregiving The American journal of psychiatry

    Key finding: Anticholinergic medication burden in schizophrenia is substantial, common, conferred by multiple medication classes, and associated with cognitive impairments across all cognitive domains. +3 more findings

  19. 2021-05-14

    Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models

    ✓ Peer-reviewed Treatments Nursing open

    Key finding: The multi-sectoral collaborative care model proposed in this study integrated resources from several departments, effectively improved the quality of life of patients and their caregivers, and provided a way of care services for patients with Alzheimer Disease.

  20. 2021-05-13

    Astrocytes and Adenosine A2A Receptors: Active Players in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Frontiers in neuroscience

    Key finding: Although, early cognitive deficits have been associated with synaptic loss and dysfunction caused by amyloid-β peptides (Aβ), accumulating evidences support a role of astrocytes in AD. +1 more finding

  21. 2021-05-13

    Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes

    ✓ Peer-reviewed Brain scans and imaging Journal of neurology

    Key finding: Significant cortical thickness reductions were identified in: lobule VII and crus I in bvFTD; lobule VI VII, crus I and II in nfvPPA; and lobule VII, crus I and II in svPPA; lobule IV, VI, VII and Crus I and II in C9 + ALSFTD. +3 more findings

  22. 2021-05-13

    Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We observed a significant CSF Aβ42 /Aβ40 × p-tau interaction on cortical neurite density index (NDI), but not orientation dispersion index or cortical thickness. +2 more findings

  23. 2021-05-13

    Cognitive Impairment in Parkinson's Disease: Epidemiology, Clinical Profile, Protective and Risk Factors

    ✓ Peer-reviewed Prevention trials Behavioral sciences (Basel, Switzerland)

    Key finding: Less is known about protective factors, although the Mediterranean diet and exercise may fall in this category. +4 more findings

  24. 2021-05-13

    Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms Nature Reviews Disease Primers

    Key finding: Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing plaques and tau-containing neurofibrillary tangles. +3 more findings

  25. 2021-05-13

    Risk factors for severity of COVID-19: a rapid review to inform vaccine prioritisation in Canada

    ✓ Peer-reviewed Disparities BMJ open

    Key finding: Increasing age (especially >60 years) may be the most important risk factor for severe outcomes. +1 more finding

Browse the library by subject, with the full score breakdown →