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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,826–7,850 of 27,380 studies, newest first · page 314 of 1096.

March 2023 25

  1. 2023-03-28

    TREM2: A new player in the tumor microenvironment

    ✓ Peer-reviewed TREM2 and immune genetics Seminars in immunology

    Key finding: Recently, TREM2 emerged as a crucial regulator of macrophage function in tumors. +3 more findings

  2. 2023-03-27

    Exploiting machine learning models to identify novel Alzheimer's disease biomarkers and potential targets

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: We further show that 70% of the upregulated hub genes (among the 28 overlapping hub genes) are AD targets based on a literature review and six miRNA (hsa-mir-16-5p, hsa-mir-34a-5p, hsa-mir-1-3p, hsa-mir-26a-5p, hsa-mir-93-5p, hsa-mir-155-5p) and one transcription factor, JUN, are associated with the upregulated hub genes.

  3. 2023-03-27

    Nutrition and cognitive health: A life course approach

    ✓ Peer-reviewed Prevention and risk Frontiers in public health

    Key finding: Mediterranean, Nordic, DASH, and MIND diets are linked to a lower risk of cognitive decline and dementia. +2 more findings

  4. 2023-03-27

    Accelerated Brain Volume Loss Caused by Anti-β-Amyloid Drugs: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Treatments Neurology

    Key finding: These findings reveal the potential for anti-Aβ therapies to compromise long-term brain health by accelerating brain atrophy and provide new insight into the adverse impact of ARIA. +3 more findings

  5. 2023-03-26
  6. 2023-03-24

    Associations between dietary patterns and dementia-related neuroimaging markers

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: A high-protein and alcohol dietary pattern was negatively associated with cortical thickness in the whole brain (Beta: -0.011; 95% confidence interval [CI]: -0.018 to -0.003), and with an Alzheimer's disease cortical thickness signature score (Beta: -0.013; 95% CI: -0.024 to -0.001). +4 more findings

  7. 2023-03-24

    Exposure to ultrafine particles and cognitive decline among older people in the United States

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: This study included 5646 participants (mean age 76 years, 65% female). +4 more findings

  8. 2023-03-24

    Therapeutic preference for Alzheimer's disease treatments: a discrete choice experiment with caregivers and neurologists

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: Caregivers and neurologists considered incremental clinical benefit over SOC and safety to be highly desirable qualities for a new drug that could clear amyloid plaques and delay clinical progression and indicated a willingness to accept incremental ARIA-E to achieve additional clinical benefits. +1 more finding

  9. 2023-03-24
  10. 2023-03-24

    Spatial disparity and factors associated with dementia mortality: A cross-sectional study in Zhejiang Province, China

    ✓ Peer-reviewed Risk factors Frontiers in Public Health

    Key finding: Thirty thousand three hundred and ninety-eight deaths attributable to dementia as the underlying or related cause (multiple causes) were reported during 2015-2019. +4 more findings

  11. 2023-03-24

    Food Insecurity and Cognitive Trajectories in Community-Dwelling Medicare Beneficiaries 65 Years and Older

    ✓ Peer-reviewed Risk factors JAMA Network Open

    Key finding: Of 3037 participants, a weighted 57.8% (raw count, 1345) were younger than 75 years, 56.2% (raw count, 1777) were women, and most (84.9% [raw count, 2268]) were White. +4 more findings

  12. 2023-03-23

    Penny-wise but Pound-foolish: The Hidden Costs of Step Therapy for Overactive Bladder

    ✓ Peer-reviewed Health systems and care delivery The Journal of Urology

    Key finding: Lenore Ackerman *Correspondence: David Geffen School of Medicine, 10833 Le Conte Ave, Box 951738, Los Angeles, CA 90095-1738 telephone: 310-794-0206; E-mail Address: [email protected] https://orcid.org/0000-0003-4192-7649 Department of Urology and Department of Obstetrics and Gynecology, Division of +4 more findings

  13. 2023-03-22

    Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats

    ✓ Peer-reviewed Drug development Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

    Key finding: Recent studies have shown that semaglutide also works on the brain, suggesting its potential utility for various diseases, including Parkinson's disease and Alzheimer's disease. +1 more finding

  14. 2023-03-22

    Targeting amyloid β in Alzheimer's disease: Meta-analysis of low-dose solanezumab in Alzheimer's disease with mild dementia studies

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Pooled MMRM analyses showed a statistically significant effect of solanezumab across cognitive and functional outcome measures. +4 more findings

  15. 2023-03-22

    Lecanemab: Appropriate Use Recommendations

    ✓ Peer-reviewed Treatments The Journal of Prevention of Alzheimer s Disease

    Lecanemab (Leqembi®) is approved in the United States for the treatment of Alzheimer's disease (AD) to be initiated in early AD (mild cognitive impairment [MCI] due to AD or mild AD dementia) with confirmed brain amyloid pathology.

  16. 2023-03-22

    Association of Bone Mineral Density and Dementia: The Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: Low bone mineral density (BMD) and dementia commonly co-occur in older individuals, with bone loss accelerating in patients with dementia due to physical inactivity and poor nutrition. +3 more findings

  17. 2023-03-21

    Therapeutic targeting of mitochondria-proteostasis axis by antioxidant polysaccharides in neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Advances in protein chemistry and structural biology

    Key finding: Despite a lack of therapies for neurodegenerative diseases, a number of interventions promoting mitochondrial integrity and protein homeostasis (proteostasis) have been shown to delay aging-associated neurodegeneration. +4 more findings

  18. 2023-03-21

    Functional and structural alterations of dorsal attention network in preclinical and early-stage Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging CNS neuroscience & therapeutics

    Key finding: The SCD and aMCI groups showed both decreased ReHo in the right middle temporal gyrus (MTG) and decreased GMV compared to healthy controls (HCs). +4 more findings

  19. 2023-03-21

    Neuronal identity defines α-synuclein and tau toxicity

    ✓ Peer-reviewed Genetics Neuron

    Key finding: Whether the underlying preferential neuronal vulnerability is a cell-type-intrinsic property or a consequence of increased expression levels remains elusive. +4 more findings

  20. 2023-03-21

    Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ 42 with Graphene Electrolyte-Gated Transistor for Alzheimer's Disease Diagnosis

    ✓ Peer-reviewed Biomarkers Analytical chemistry

    Key finding: Despite significant progress in the methodologies for detecting AD core biomarkers such as Aβ 42 from serum/plasma, there remains cautious optimism going forward due to its controversial diagnostic value and disease relevance. +2 more findings

  21. 2023-03-21

    Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination

    ✓ Peer-reviewed TREM2 and immune genetics Cell reports

    Key finding: The cuprizone mouse model is widely used to simulate demyelination and remyelination occurring in these diseases. +3 more findings

  22. 2023-03-20

    Glucagon-like peptide-1 receptor agonists to expand the healthy lifespan: Current and future potentials

    ✓ Peer-reviewed Drug development Aging cell

    Key finding: To help ensure an expanded healthy lifespan for as many people as possible worldwide, there is a need to prevent or manage a number of prevalent chronic diseases directly and indirectly closely related to aging, including diabetes and obesity. +4 more findings

  23. 2023-03-20

    Blood biomarkers in mild cognitive impairment patients: Relationship between analytes and progression to Alzheimer disease dementia

    ✓ Peer-reviewed Biomarkers European journal of neurology

    Key finding: Blood-based biomarkers are promising tools for the diagnosis of Alzheimer disease (AD) at prodromal stages (mild cognitive impairment [MCI]) and are hoped to be implemented as screening tools for patients with cognitive complaints.

  24. 2023-03-19

    Assessing preparedness for Alzheimer disease‐modifying therapies in Australasian health care systems

    ✓ Peer-reviewed Treatments The Medical Journal of Australia

    Key finding: Three deaths have been reported related to treatment with lecanemab.6 Patients receiving DMT require frequent monitoring with MRI brain scans (four or more per year), as there is a high rate of clinically significant amyloid-related imaging abnormalities (ARIA), both brain oedema (ARIA-E) and macro- and microhaemorrhages (ARIA-H). +4 more findings

  25. 2023-03-18

    Low-Dose Whole Brain Radiation Therapy for Alzheimer's Dementia: Results From a Pilot Trial in Humans

    ✓ Peer-reviewed Treatments International journal of radiation oncology, biology, physics

    Key finding: Our results from 5 patients with eAD treated with LD-WBRT (10 Gy in 5 fractions) demonstrate a positive safety profile and provide preliminary, hypothesis-generating data to suggest that this treatment stabilizes or improves cognition. +2 more findings

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