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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,576–16,600 of 27,380 studies, newest first · page 664 of 1096.

November 2015 18

  1. 2015-11-03

    Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: As reported recently, we found evidence for fitness-related perfusion changes of the aged human hippocampus that were closely linked to changes in episodic memory function. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2015-11-03

    Basal forebrain control of wakefulness and cortical rhythms

    ✓ Peer-reviewed Risk factors Nature communications

    Key finding: Here we show that genetically targeted chemogenetic activation of BF cholinergic or glutamatergic neurons in behaving mice produced significant effects on state consolidation and/or the electroencephalogram but had no effect on total wake. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-11-02

    Sleep problems and associated comorbidities among adults with Down syndrome

    ✓ Peer-reviewed Risk factors Journal of intellectual disability research : JIDR

    Key finding: Sleep apnoea was associated with more common other respiratory concerns, and more frequent visits to physicians, but not with some expected medical comorbidities (cardiac). +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-11-02

    Is the Mediterranean diet a feasible approach to preserving cognitive function and reducing risk of dementia for older adults in Western countries? New insights and future directions

    ✓ Peer-reviewed Prevention trials Ageing research reviews

    Key finding: Evidence from recent studies has revealed modification of lifestyle and dietary behaviours is, at present, the best means of prevention. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2015-11-02

    Effects of education and race on cognitive decline: An integrative study of generalizability versus study-specific results

    ✓ Peer-reviewed Disparities Psychology and aging

    Key finding: We compare data across studies, we harmonized estimates of common latent factors representing overall or general cognitive performance, memory, and executive function derived from the: (a) Washington Heights, Hamilton Heights, Inwood Columbia Aging Project (N = 4,115), (b) Spanish and English Neuropsychological Assessment Scales (N = 525), (c) Duke Memory, Health, and Aging study (N = 578), and (d) Neurocognitive Outcomes of Depression in the Elderly (N = 585). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-11 month only

    Palliative and end-of-life decision-making in dementia care

    ✓ Peer-reviewed End-of-life care International journal of palliative nursing

    Key finding: This paper will highlight some of the pertinent issues associated with palliative and end-of-life decision-making in relation to dementia.

    Full summary, score breakdown and related studies → Original source

  7. 2015-11 month only

    Pimavanserin

    ✓ Peer-reviewed Clinical trials Drugs of today (Barcelona, Spain : 1998)

    Key finding: Most antipsychotic medications worsen motor dysfunction due to dopamine antagonism, and all carry a black box warning for an increased risk of mortality in elderly patients with dementia-related psychosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-11 month only

    Memantine ER/Donepezil: A Review in Alzheimer's Disease

    ✓ Peer-reviewed Treatments CNS drugs

    Key finding: In a 24-week, phase III trial in patients with moderate to severe AD, addition of memantine ER 28 mg once daily to stable cholinesterase inhibitor (ChEI) therapy was more effective than add-on placebo on measures of cognition, global clinical status, dementia behaviour and semantic processing ability, although between-group differences on a measure of daily function did not significantly differ. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2015-11-01

    Establishment and Dysfunction of the Blood-Brain Barrier

    ✓ Peer-reviewed Vascular contributions Cell

    Key finding: Structural and functional brain connectivity, synaptic activity, and information processing require highly coordinated signal transduction between different cell types within the neurovascular unit and intact blood-brain barrier (BBB) functions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-11-01

    microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain

    ✓ Peer-reviewed Drug development The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Mounting evidence suggests that apolipoprotein E (ApoE) is involved in Aβ metabolism.

    Full summary, score breakdown and related studies → Original source

  11. 2015-11-01

    Association Between Atrial Fibrillation and Dementia in the General Population

    ✓ Peer-reviewed Long-term cohort studies JAMA neurology

    Key finding: Atrial fibrillation (AF) has been suggested as a risk factor for dementia since it may lead to chronic cerebral hypoperfusion and stroke. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-11-01

    Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease

    ✓ Peer-reviewed Mild cognitive impairment JAMA neurology

    Key finding: Baseline CSF levels of NGRN in patients with AD (median level, 2381 pg/mL [interquartile range, 1651-3416 pg/mL]) were higher than in cognitively normal participants (median level, 1712 pg/mL [interquartile range, 1206-2724 pg/mL]) (P = .04). +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2015-11-01

    Vitamin D Status and Rates of Cognitive Decline in a Multiethnic Cohort of Older Adults

    ✓ Peer-reviewed Disparities JAMA neurology

    Key finding: (N = 382 at baseline) had a mean (SD) age of 75.5 (7.0) years; 61.8% were women; and 41.4% were white, 29.6% African American, 25.1% Hispanic, and 3.9% other race/ethnicity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-11-01

    The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial

    ✓ Peer-reviewed Prevention and risk Journal of the American Medical Directors Association

    Key finding: Scale of benefit is comparable with in-person training, indicating its potential as a public health intervention. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-11-01

    Naturally Occurring Monoclonal Antibodies and Their Therapeutic Potential for Neurologic Diseases

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Many insults, including trauma, ischemia, infection, inflammation, and neurodegeneration, result in irreversible damage to the central nervous system. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-11-01

    Early Statin Use and the Progression of Alzheimer Disease: A Total Population-Based Case-Control Study

    ✓ Peer-reviewed Treatments Medicine

    Key finding: After adjusting for other covariates, mild-to-moderate AD patients with early stain use exhibited a 0.85-risk (95% CI = 0.76-0.95, P = 0.0066) to have AD progression than those without. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2015-11-01

    Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Avagacestat did not demonstrate efficacy and was associated with adverse dose-limiting effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-11-01

    Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

    ✓ Peer-reviewed Biomarkers Oncotarget

    Key finding: Sixteen exosomal miRNAs were up regulated and 11 miRNAs were under regulated significantly in PD CSF when compared with those in healthy controls (relative fold > 2, p < 0.05). +4 more findings

    Full summary, score breakdown and related studies → Original source

October 2015 7

  1. 2015-10-31

    Family caregivers of patients with frontotemporal dementia: An integrative review

    ✓ Peer-reviewed Caregiving International journal of nursing studies

    Key finding: Family caregivers of patients with frontotemporal dementia identify behavioral disturbances as most troubling. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-10-31

    Rural-Urban Differences in Alzheimer's Disease and Related Disorders Diagnostic Prevalence in Kentucky and West Virginia

    ✓ Peer-reviewed Risk factors The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

    Key finding: After adjusting for state, average beneficiary age, percent of female beneficiaries, percent of beneficiaries eligible for Medicaid in each county, Central Appalachian county, percent of age-eligible residents enrolled in Medicare, and percent of residents under age 65 enrolled in Medicare in our adjusted models, we found that 2013 ADRD diagnostic prevalence was 11% lower in rural counties (95% CI: 9%-13%). +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2015-10-30

    Cognitive training in Parkinson disease: A systematic review and meta-analysis

    ✓ Peer-reviewed Prevention trials Neurology

    Key finding: Though still small, the current body of RCT evidence indicates that CT is safe and modestly effective on cognition in patients with mild to moderate PD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-10-29

    Montreal Cognitive Assessment for the diagnosis of Alzheimer's disease and other dementias

    ✓ Peer-reviewed Cognitive tests and assessment The Cochrane database of systematic reviews

    Key finding: Dementia is a progressive syndrome of global cognitive impairment with significant health and social care costs. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-10-29

    The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain

    ✓ Peer-reviewed Risk genes beyond APOE Progress in neurobiology

    Key finding: In the central nervous system, ADAM10 has attracted the most attention, since it was described as the amyloid precursor protein α-secretase over ten years ago. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-10-29

    GATA1-mediated transcriptional regulation of the γ-secretase activating protein increases Aβ formation in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of neurology

    Key finding: Because of an extra copy of the Aβ precursor protein gene on chromosome 21, Down syndrome (DS) individuals develop high levels of Aβ peptides and Alzheimer disease-like brain amyloidosis early in life. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-10-27

    The Montreal Cognitive Assessment: Creating a Crosswalk with the Mini-Mental State Examination

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: Scores on the full and abbreviated versions of the MoCA can be linked directly to the MMSE.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →