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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,576–11,600 of 27,380 studies, newest first · page 464 of 1096.

June 2020 14

  1. 2020-06-01

    Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

    ✓ Peer-reviewed Genetics Cell reports

    Key finding: Analyses of whole-tissue RNA-seq and single-cell/nucleus RNA-seq datasets corroborate our findings and suggest that the lack of DAM response in human microglia occurs specifically in AD tissues, not other neurodegenerative settings. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2020-06-01

    Attitudes and Use of Information and Communication Technologies in Older Adults With Mild Cognitive Impairment or Early Stages of Dementia and Their Caregivers: Cross-Sectional Study

    ✓ Peer-reviewed Cognitive tests and assessment Journal of medical Internet research

    Key finding: However, there are barriers to their use associated with sociodemographic factors and negative attitudes, as well as inadequate knowledge about technologies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-06-01

    Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: BvFTD shows significant symptomatic overlap with non-degenerative primary psychiatric disorders including major depressive disorder, bipolar disorder, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders and even personality disorders.

    Full summary, score breakdown and related studies → Original source

  4. 2020-06-01

    Identification of Conserved Proteomic Networks in Neurodegenerative Dementia

    ✓ Peer-reviewed Disease mechanisms Cell reports

    Key finding: Genetic risk enriches in modules changing early in disease and indicates that AD and PSP have distinct causal biological drivers at the pathway level, despite aspects of similar pathology, including synaptic loss and glial inflammatory changes.

    Full summary, score breakdown and related studies → Original source

  5. 2020-06-01

    Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Lancet

    Between Feb 1, 2013, and June 28, 2019 (Barcelona), and between June 1, 2009, and Dec 31, 2014 (Cambridge), we included 388 participants with Down syndrome (257 [66%] asymptomatic, 48 [12%] with prodromal Alzheimer's disease, and 83 [21%] with Alzheimer's disease dementia) and 242 euploid controls.

    Full summary, score breakdown and related studies → Original source

  6. 2020-06-01

    1414-P: Characteristics Associated with Sulfonylureas and Basal Insulin Use following Metformin in Older Adults

    ✓ Peer-reviewed Health systems and care delivery Diabetes

    Key finding: Further research is needed to elucidate factors underlying differences in SFU and BI prescribing patterns. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-06-01

    4430 Coffee Shops and Fast-food Restaurants: Potential Neighborhood Resources for Cognitive Health and Wellbeing Among Aging Americans

    ✓ Peer-reviewed Risk factors Journal of Clinical and Translational Science

    Key finding: OF IMPACT: The results contribute new evidence towards an emerging ecological model of cognitive health. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-06-01

    The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

    ✓ Peer-reviewed TREM2 and immune genetics Cell

    Key finding: In all three cases, recent discoveries establish the TREM2 receptor as a major pathology-induced immune signaling hub that senses tissue damage and activates robust immune remodeling in response to it. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2020-06-01

    Associations Between Self-Reported Sensory Impairment and Risk of Cognitive Decline and Impairment in the Health and Retirement Study Cohort

    ✓ Peer-reviewed Prevention and risk The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Self-assessed sensory impairment is independently associated with cognitive decline and incident possible CIND and probable dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-06-01

    HIITing the brain with exercise: mechanisms, consequences and practical recommendations

    ✓ Peer-reviewed Prevention and risk The Journal of physiology

    Key finding: However, the time commitment associated with MICT is a potential barrier to participation, and high-intensity interval training (HIIT) has since emerged as a more time-efficient mode of exercise that can promote similar if not indeed superior improvements in cardiorespiratory fitness for a given training volume and further promote vascular adaptation.

    Full summary, score breakdown and related studies → Original source

  11. 2020-06-01

    Development and validation of an interpretable deep learning framework for Alzheimer's disease classification

    ✓ Peer-reviewed Prevention and risk Brain : a journal of neurology

    Key finding: Our framework linked a fully convolutional network, which constructs high resolution maps of disease probability from local brain structure to a multilayer perceptron and generates precise, intuitive visualization of individual Alzheimer's disease risk en route to accurate diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-06-01

    Type 2 diabetes and cognitive dysfunction-towards effective management of both comorbidities

    ✓ Peer-reviewed Prevention and risk The lancet. Diabetes & endocrinology

    Key finding: Although type 2 diabetes is associated with an increased risk of dementia, awareness of the link between the two conditions is poor, and few recommendations are available to guide clinicians about how to approach cognitive dysfunction in people with diabetes.

    Full summary, score breakdown and related studies → Original source

  13. 2020-06-01

    Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults: A Secondary Analysis of a Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Of 157 participants initially assessed, 137 were enrolled in the Age-Well clinical trial, and 127 were analyzed in this study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-06-01

    Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: The large number of participants screened with amyloid positron emission tomography (PET) and standardized assessments provides an unprecedented opportunity to evaluate factors associated with elevated brain amyloid. +4 more findings

    Full summary, score breakdown and related studies → Original source

May 2020 11

  1. 2020-05-31

    The use of technology in creating individualized, meaningful activities for people living with dementia: A systematic review

    ✓ Peer-reviewed Digital health tools Dementia (London, England)

    Key finding: A narrative synthesis of the results grouped the various technologies into four main purposes: reminiscence/memory support, behavior management, stimulating engagement, and conversation/communication support. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-05-30

    Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model

    ✓ Peer-reviewed Risk factors Biochimica et biophysica acta. Molecular basis of disease

    Key finding: Deletion of Sirt3 gene has been reported to result in the acceleration of MetS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-05-30

    Prevention of Disease-related Mortality from Chronic Non-communicable Diseases

    ✓ Peer-reviewed Risk factors Clinical Social Work and Health Intervention

    Key finding: The disease-related mortality from chronic non-communicable diseases is an emerging issue of global health in middle to high income countries.

    Full summary, score breakdown and related studies → Original source

  4. 2020-05-30

    Association of body mass index with risk of cognitive impairment and dementia: A systematic review and meta-analysis of prospective studies

    ✓ Peer-reviewed Prevention and risk Neuroscience and biobehavioral reviews

    Key finding: Meta-analysis showed that midlife underweight, obesity and late-life underweight conferred 1.39-, 1.31- and 1.64-fold excess risk for cognitive impairment and dementia, while late-life overweight and obesity conferred 21% and 25% reduced risk. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2020-05-29

    Measuring dementia incidence within a cohort of 267,153 older Australians using routinely collected linked administrative data

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: Estimated age-standardised dementia incidence rates using all linked datasets was 16.8 cases per 1000 person years for people aged 65+. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-05-29

    Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances

    ✓ Peer-reviewed Disease mechanisms Molecular neurodegeneration

    Key finding: Although the detailed mechanism of the pathogenesis of AD is still elusive, a large body of evidence suggests that damaged mitochondria likely play fundamental roles in the pathogenesis of AD.

    Full summary, score breakdown and related studies → Original source

  7. 2020-05-29

    Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease

    ✓ Peer-reviewed Prevention trials European journal of nutrition

    Key finding: In line with data from elderly population samples, Mediterranean and MIND diet and some data-derived dietary patterns were related to memory and language function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-05-28

    Microbiota-gut-brain axis in health and disease: Is NLRP3 inflammasome at the crossroads of microbiota-gut-brain communications?

    ✓ Peer-reviewed Disease mechanisms Progress in neurobiology

    Key finding: In particular, though no direct and causal correlation among altered gut microbiota, NLRP3 activation and brain pathology has been demonstrated and in-depth studies are needed in this setting, our purpose was to pave the way to a novel and pioneering perspective on the pathophysiology of CNS disorders.

    Full summary, score breakdown and related studies → Original source

  9. 2020-05-28

    The Role of the Gastrointestinal Mucus System in Intestinal Homeostasis: Implications for Neurological Disorders

    ✓ Peer-reviewed Disease mechanisms Frontiers in cellular and infection microbiology

    Key finding: The gut has its own intrinsic neuronal network, the enteric nervous system, which extends the length of the GI tract and innervates the mucosal epithelium. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-05-28

    Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease

    ✓ Peer-reviewed Hippocampus size on brain scans Annals of neurology

    Key finding: Nilotinib is safe and achieves pharmacologically relevant cerebrospinal fluid concentrations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-05-28

    TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: Neuroinflammation is an important host defense response to secondary brain injury after intracerebral hemorrhage (ICH). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →