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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,351–10,375 of 27,380 studies, newest first · page 415 of 1096.

April 2021 7

  1. 2021-04-01

    The role of innate immune genes in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Current opinion in neurology

    Key finding: The aim of this study was to provide an update on the role of the innate immune system and neuroinflammation in the pathogenesis of Alzheimer's disease, with an emphasis on microglial receptors CD33 and TREM2. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-04-01

    An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's research & therapy

    Key finding: Applying an integrative multi-omics approach we report novel molecular and pathways alterations associated with AD pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-04-01

    Association Between Age at Diabetes Onset and Subsequent Risk of Dementia

    ✓ Peer-reviewed Risk factors JAMA

    Key finding: Among 10 095 participants (67.3% men; aged 35-55 years in 1985-1988), a total of 1710 cases of diabetes and 639 cases of dementia were recorded over a median follow-up of 31.7 years. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-04-01

    Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review

    ✓ Peer-reviewed Digital health tools Journal of imaging

    Key finding: We found 129 articles that applied transfer learning to MR brain imaging tasks. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-04-01

    Effect of Sodium Benzoate on Cognitive Function Among Patients With Behavioral and Psychological Symptoms of Dementia: Secondary Analysis of a Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: These findings suggest that benzoate treatment may improve cognitive function in women with later-phase dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-04-01

    Sex-related Differences in Tau Positron Emission Tomography (PET) and the Effects of Hormone Therapy (HT)

    ✓ Peer-reviewed Biomarkers Alzheimer disease and associated disorders

    Key finding: Regional sex-related differences in tau PET burden may contribute to the disparities in AD prevalence between males and females. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-04-01

    Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Exclusion criteria included any significant neurologic disorder other than suspected AD; presence of infection, infarction, or multiple lacunes as detected by magnetic resonance imaging; and any significant systemic condition that could lead to difficulty complying with the protocol. +2 more findings

    Full summary, score breakdown and related studies → Original source

March 2021 18

  1. 2021-03-31

    Plasma P-tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Plasma P-tau181/Aβ42 ratio may be a noninvasive means of identifying AD with elevated brain amyloid in populations with concomitant CeVD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-03-31

    Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Ageing research reviews

    Key finding: Astrocyte reactivity is a hallmark of neuroinflammation that arises with Alzheimer's disease (AD) and nearly every other neurodegenerative condition. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-03-31

    Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer's disease (MCI and dementia) in primary care: a review and synthesis

    ✓ Peer-reviewed Brain tissue and pathology Journal of internal medicine

    Key finding: Our understanding of AD has grown substantially: no longer conceptualized as a late-in-life syndrome of cognitive and functional impairments, we now recognize that AD pathology builds silently for decades before cognitive impairment is detectable. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-03-31

    Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis

    ✓ Peer-reviewed Brain tissue and pathology Neurobiology of disease

    Key finding: FTD and ALS are linked by shared genetic causes (e.g. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-03-31

    Machine Learning Driven Profiling of Cerebrospinal Fluid Core Biomarkers in Alzheimer's Disease and Other Neurological Disorders

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: In this context, unsupervised machine learning approaches may overcome these issues providing unbiased cut-off values and data-driven patient stratification according to the sole distribution of biomarkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-03-31

    Dementia caregiving across Latin America and the Caribbean and brain health diplomacy

    ✓ Peer-reviewed Digital health tools The lancet. Healthy longevity

    Key finding: We reviewed the major challenges to caregiving in Latin America and the Caribbean, and we propose regional and coordinated actions to drive future change. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-03-31

    Prevention of cognitive decline in subjective cognitive decline APOE ε4 carriers after EGCG and a multimodal intervention (PENSA): Study design

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (New York, N. Y.)

    Key finding: The use of new technologies (i.e., mobile ecological momentary assessments [EMAs], activity tracker) in the PENSA study allows the collection of continuous data on lifestyle behaviors (diet and physical activity) and mood, enabling a personalized design as well as an intensive follow-up of participants. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-03-31

    Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease

    ✓ Peer-reviewed Biomarkers Brain connectivity

    Key finding: The gFC was reduced in MC compared with NC participants. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-03-30

    Cognitive and Behavioral Manifestations in ALS: Beyond Motor System Involvement

    ✓ Peer-reviewed Digital health tools Diagnostics (Basel, Switzerland)

    Key finding: ALS-FTSD patients have a worse prognosis and shorter survival rates than patients with ALS or frontotemporal dementia alone. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-03-29

    Loneliness and Neurocognitive Aging

    ✓ Peer-reviewed Risk factors Advances in geriatric medicine and research

    Key finding: Loneliness imposes significant risks to physical, mental and brain health in older adulthood.

    Full summary, score breakdown and related studies → Original source

  11. 2021-03-29

    Sleep Disorders and Cognitive Dysfunctions in Parkinson's Disease: A Meta-Analytic Study

    ✓ Peer-reviewed Risk factors Neuropsychology review

    Key finding: We included studies published in peer-reviewed journals in English providing results about neuropsychological comparison between patients with or without sleep disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-03-29

    Polygenic Score Models for Alzheimer's Disease: From Research to Clinical Applications

    ✓ Peer-reviewed Genetics Frontiers in neuroscience

    Key finding: Recent epidemiological and genetics studies have revealed the polygenic nature of the disease, which is possibly explainable by a polygenic score model that considers multiple genetic risks.

    Full summary, score breakdown and related studies → Original source

  13. 2021-03-29

    The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

    ✓ Peer-reviewed Cognitive tests and assessment BMJ

    The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found.

    Full summary, score breakdown and related studies → Original source

  14. 2021-03-29

    Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages

    ✓ Peer-reviewed TREM2 and immune genetics Life science alliance

    Key finding: We implanted biomaterial scaffolds, which act as an artificial premetastatic niche, into immunocompetent tumor-bearing and control mice, and identified a unique tumor-specific gene expression signature that includes high expression of C1qa , C1qb , Trem2 , and Chil3 Single-cell RNA sequencing mapped these genes to two distinct macrophage populations in the scaffolds, one marked by elevated C1qa , C1qb , and Trem2 , the other with high Chil3 , Ly6c2 and Plac8 In mice, expression of these genes in the corresponding populations was elevated in tumor-associated macrophages compared with macrophages in the normal pancreas. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-03-29

    Voice-Based Conversational Agents for the Prevention and Management of Chronic and Mental Health Conditions: Systematic Literature Review

    ✓ Peer-reviewed Digital health tools Journal of medical Internet research

    Key finding: Of 7170 prescreened papers, 12 met the inclusion criteria. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2021-03-29

    Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries

    ✓ Peer-reviewed Caregiving British journal of sports medicine

    Key finding: The global burden associated with physical inactivity is substantial. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-03-27

    Early detection of amyloid load using 18F-florbetaben PET

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: SUVR using the whole cerebellum as the reference region and centiloid (CL) cutoffs for early and established amyloid pathology were 1.10 (13.5 CL) and 1.24 (35.7 CL), respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-03-27

    Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Baseline plasma GFAP could detect abnormal CSF Aβ42/40 and CSF Aβ42/T-tau with an AUC of 0.79 (95% CI 0.72-0.86) and 0.80 (95% CI 0.72-0.86), respectively. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →