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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 22,826–22,850 of 27,380 studies, newest first · page 914 of 1096.

January 2007 4

  1. 2007-01-01

    Memantine treatment of cognitive symptoms in mild to moderate Alzheimer disease: secondary analyses from a placebo-controlled randomized trial

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: As assessed by the ADAS-cog total score, participants in the placebo group demonstrated significantly more cognitive decline from baseline than participants treated with memantine at all visits beginning at week 8. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2007-01-01

    Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease

    ✓ Peer-reviewed Treatments Neuropsychiatric disease and treatment

    Key finding: Lack of supportive evidence for SSRIs as cognition enhancers or disease modifiers in AD is the result of omissions in clinical trial design, as opposed to reporting of negative outcomes.

    Full summary, score breakdown and related studies → Original source

  3. 2007-01-01

    Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness

    ✓ Peer-reviewed Genetics Medicine and science in sports and exercise

    Key finding: The preliminary findings from this study support the possibility that aerobic fitness is positively associated with the memory performance of those individuals at most genetic risk for Alzheimer disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2007-01-01

    Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

    ✓ Peer-reviewed Genetics Nature genetics

    Key finding: In addition to identifying the epsilon4 allele of APOE and related effects, we pinpointed over a dozen potential Alzheimer disease susceptibility genes (ACE, CHRNB2, CST3, ESR1, GAPDHS, IDE, MTHFR, NCSTN, PRNP, PSEN1, TF, TFAM and TNF) with statistically significant allelic summary odds ratios (ranging from 1.11-1.38 for risk alleles and 0.92-0.67 for protective alleles).

    Full summary, score breakdown and related studies → Original source

December 2006 21

  1. 2006-12-30

    Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Hippocampal sclerosis (HS) is characterized by selective neuronal loss and gliosis in CA1 and the subiculum and has been associated with several disorders, including Alzheimer's disease, frontotemporal lobar degeneration with ubiquitin immunoreactive inclusions (FTLD-U), vascular dementia and some tauopathies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-12-29

    The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism

    ✓ Peer-reviewed Lewy body dementia Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Emerging evidence, however, suggests that loss of essential functions of PS could better explain dementia and neurodegeneration in AD.

    Full summary, score breakdown and related studies → Original source

  3. 2006-12-19

    Development of a new measure of health-related quality of life for people with dementia: DEMQOL

    ✓ Peer-reviewed Caregiving Psychological medicine

    Key finding: DEMQOL and DEMQOL-Proxy show psychometric properties that are comparable with the best available dementia-specific measures of HRQL.

    Full summary, score breakdown and related studies → Original source

  4. 2006-12-18

    A review of screening tests for cognitive impairment

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: In this review, we sought to ascertain the number of screening tools currently available, and to examine the evidence for their validity in detecting different diagnoses in a variety of populations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-12-14

    Systematic review of the effect of psychological interventions on family caregivers of people with dementia

    ✓ Peer-reviewed Caregiving Journal of affective disorders

    Key finding: We found excellent evidence for the efficacy of six or more sessions of individual behavioral management therapy centered on the care recipient's behavior in alleviating caregiver symptoms both immediately and for up to 32 months. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-12-12

    Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry

    ✓ Peer-reviewed Hippocampus size on brain scans Neurotoxicology and teratology

    Key finding: Aberrations in hippocampal asymmetry and left hippocampal volumes were found for adolescent heavy drinkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2006-12-08

    Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: systematic review and meta-analyses

    ✓ Peer-reviewed How common it is BMJ (Clinical research ed.)

    Key finding: There is some evidence that multifaceted interventions in hospital reduce the number of falls and that use of hip protectors in care homes prevents hip fractures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2006-12-07

    Brain-derived neurotrophic factor (BDNF) and type 2 diabetes

    ✓ Peer-reviewed Risk factors Diabetologia

    Key finding: Low levels of BDNF accompany impaired glucose metabolism. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2006-12-06

    Application and comparison of classification algorithms for recognition of Alzheimer's disease in electrical brain activity (EEG)

    ✓ Peer-reviewed Digital health tools Journal of neuroscience methods

    Key finding: Based on 10-fold cross-validation runs it could be demonstrated that even tough modern computer-intensive classification algorithms such as random forests, SVM and neural networks show a slight superiority, more classical classification algorithms performed nearly equally well.

    Full summary, score breakdown and related studies → Original source

  10. 2006-12-06

    The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

    ✓ Peer-reviewed Inflammation and the immune system Progress in neurobiology

    Key finding: Measuring microglial activation in vivo in patients suffering from these diseases may help chart progression of neuroinflammation as well as assess efficacy of therapies designed to modulate neuroinflammation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2006-12-01

    Gamma Linolenic Acid: An Antiinflammatory Omega-6 Fatty Acid

    ✓ Peer-reviewed Prevention and risk Current Pharmaceutical Biotechnology

    Key finding: The PUFAs of omega-3 and omega-6 series play a significant role in health and disease by generating potent modulatory molecules for inflammatory responses, including eicosanoids (prostaglandins, and leukotrienes), and cytokines (interleukins) and affecting the gene expression of various bioactive molecules. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2006-12 month only

    Sex- and APOE isoform-dependent effects of radiation on cognitive function

    ✓ Peer-reviewed Genetics Radiation research

    Key finding: Compared to APOE3, APOE4 increases while APOE2 decreases the risk of developing age-related cognitive decline and Alzheimer's disease, particularly in women. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2006-12-01

    Mechanisms of Disease: astrocytes in neurodegenerative disease

    ✓ Peer-reviewed Inflammation and the immune system Nature clinical practice. Neurology

    Key finding: The term neurodegenerative disease refers to the principal pathology associated with disorders such as amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease and Parkinson's disease, and it is presumed that neurodegeneration results in the clinical findings seen in patients with these diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2006-12-01

    Function and biological roles of the Dickkopf family of Wnt modulators

    ✓ Peer-reviewed Brain scans and imaging Oncogene

    Key finding: Dickkopf (Dkk) genes comprise an evolutionary conserved small gene family of four members (Dkk1-4) and a unique Dkk3-related gene, Dkkl1 (soggy). +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2006-12-01

    AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: Recent studies indicate that this peptide can drive loss of surface AMPA and NMDA type glutamate receptors.

    Full summary, score breakdown and related studies → Original source

  16. 2006-12-01

    Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Statins may modulate the phosphorylation of tau in humans and this effect may depend on the CNS availability of the statin. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2006-12-01

    Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease

    ✓ Peer-reviewed Vascular contributions Archives of neurology

    Key finding: Persons with MCI also have impaired motor function, and the degree of impairment in lower extremity function is related to the risk of AD.

    Full summary, score breakdown and related studies → Original source

  18. 2006-12-01

    Serotonin transporter gene variants and behavior: a comprehensive review

    ✓ Peer-reviewed Hippocampus size on brain scans Current drug targets

    Key finding: A key molecular structure of this system, the serotonin transporter (SERT) gene, has been associated with many human behaviors, both normal and pathological.

    Full summary, score breakdown and related studies → Original source

  19. 2006-12-01

    Clinical utility of office-based cognitive predictors of fitness to drive in persons with dementia: A systematic review

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Without validated cutoff scores, it is impossible to employ tests in a standardized fashion in front-line clinical settings.

    Full summary, score breakdown and related studies → Original source

  20. 2006-12-01

    Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia

    ✓ Peer-reviewed Clinical safety The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: The demonstration that isoflurane contributes to well-described mechanisms of Alzheimer's neuropathogenesis provides a plausible link between the acute effects of anesthesia, a well-described risk factor for delirium, and the more long-term sequelae of dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2006-12-01

    Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers

    ✓ Peer-reviewed Disease mechanisms Annals of neurology

    Key finding: A small, orally available natural product penetrates into the brain in vivo to rescue the memory impairment produced by soluble Abeta oligomers through a mechanism that restores hippocampal synaptic plasticity.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →