Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 9,601–9,625 of 27,380 studies, newest first · page 385 of 1096.
November 2021 25
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2021-11-19
A national cohort study (2000-2018) of long-term air pollution exposure and incident dementia in older adults in the United States
50/100 ✓ Peer-reviewed Risk factors Nature communications
Key finding: Our study suggests that exposures to PM 2.5 and NO 2 are associated with incidence of dementia and AD.
Full summary, score breakdown and related studies → Original source
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2021-11-18
Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau
45/100 ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications
Key finding: Alzheimer's disease (AD) is associated with inner retina (nerve fiber and ganglion cell layers) thinning. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-18
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
40/100 ✓ Peer-reviewed Genetics Neuron
Key finding: Integrated cross-species analysis revealed robust transcriptomic and histologic signatures of neurogenesis in the adult mouse, pig, and macaque but not humans. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-17
Using smartphone technology to improve prospective memory functioning: A randomized controlled trial
65/100 ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society
Key finding: Older adults with cognitive disorders can learn smartphone-based memory strategies and doing so benefits prospective memory functioning and independence. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-17
Impact of herpes zoster vaccination on incident dementia: A retrospective study in two patient cohorts
59/100 ✓ Peer-reviewed Disparities PloS one
Key finding: HZ vaccination is associated with reduced risk of dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-17
Plasma neurofilament light chain protein is not increased in treatment-resistant schizophrenia and first-degree relatives
49/100 ✓ Peer-reviewed Biomarkers The Australian and New Zealand journal of psychiatry
Key finding: Treatment-resistant schizophrenia does not appear to be associated with neuronal, particularly axonal degeneration. +3 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-16
Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion
41/100 ✓ Peer-reviewed Risk factors Frontiers in immunology
Key finding: Cerebrovascular pathologies are commonly associated with dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-16
Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
66/100 ✓ Peer-reviewed Prevention and risk PLoS medicine
Key finding: Intake of coffee alone or in combination with tea was associated with lower risk of poststroke dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-15
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline
40/100 ✓ Peer-reviewed Disease mechanisms Trends in endocrinology and metabolism: TEM
Key finding: Type 2 diabetes (T2D) is associated with multiple comorbidities, including diabetic retinopathy (DR) and cognitive decline, and T2D patients have a significantly higher risk of developing Alzheimer's disease (AD). +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-15
Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
55/100 ✓ Peer-reviewed Prevention and risk Nutrients
Key finding: Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results.
Full summary, score breakdown and related studies → Original source
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2021-11-13
Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer's amyloid, tau and FDG PET status
66/100 ✓ Peer-reviewed Biomarkers Translational psychiatry
Key finding: We found plasma p-tau181 significantly correlated with brain amyloid (Spearman ρ = 0.45, P < 0.0001), tau (0.25, P = 0.0003), and FDG PET uptakes (-0.37, P < 0.0001), and increased along the Alzheimer's continuum. +2 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-12
Design and Development of a Community-Based, Interdisciplinary, Collaborative Dementia Care Program
48/100 ✓ Peer-reviewed Caregiving The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Key finding: Served dyads from three primary care clinics with a total of 87 dyads enrolled between December 2018 and June 2020. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-11
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
43/100 ✓ Peer-reviewed Genetics Nature biotechnology
Key finding: Here we present Scissor, a method that identifies cell subpopulations from single-cell data that are associated with a given phenotype. +2 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-11
Cardiovascular risk prediction in healthy older people
68/100 ✓ Peer-reviewed Digital health tools GeroScience
Key finding: Identification of individuals with increased risk of major adverse cardiovascular events (MACE) is important.
Full summary, score breakdown and related studies → Original source
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2021-11-10
Total cost of care increases significantly from early to mild Alzheimer's disease: 5-year ALSOVA follow-up
50/100 ✓ Peer-reviewed Caregiving Age and ageing
Key finding: Total cost of care in early stage AD (CDR-SB ≤ 4) was 16,448€ (95% CI 13,722-19,716) annually. +4 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-10
The role of pathological tau in synaptic dysfunction in Alzheimer's diseases
41/100 ✓ Peer-reviewed Disease mechanisms Translational neurodegeneration
Key finding: Accumulating evidence suggests that synaptic dysfunction could be an early pathological event in AD.
Full summary, score breakdown and related studies → Original source
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2021-11-10
Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health
41/100 ✓ Peer-reviewed Disease mechanisms Nutrition reviews
Key finding: Extra-virgin olive oil (EVOO), a popular functional food and major source of fat in the Mediterranean diet, possesses a variety of healthful components, including monounsaturated fatty acids and bioactive phenolic compounds that, individually and collectively, exert beneficial effects on cardiometabolic markers of health and act as neuroprotective agents through their anti-inflammatory and antioxidant activities. +3 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-10
Mild behavioral impairment correlates of cognitive impairments in older adults without dementia: mediation by amyloid pathology
60/100 ✓ Peer-reviewed Long-term cohort studies Translational psychiatry
Key finding: The purpose of the study is to examine the roles of the AD imaging pathologies in modulating the associations of MBI with cognitive impairments. +3 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-09
Retinal imaging biomarkers of neurodegenerative diseases
41/100 ✓ Peer-reviewed Brain scans and imaging Clinical & experimental optometry
Key finding: Whilst research findings are promising, efforts to harmonise study designs and imaging methods will be important in translating these findings into clinical care.
Full summary, score breakdown and related studies → Original source
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2021-11-09
The role of multimodal MRI in mild cognitive impairment and Alzheimer's disease
48/100 ✓ Peer-reviewed Brain scans and imaging Journal of neuroimaging : official journal of the American Society of Neuroimaging
Key finding: Classification of MCI and HC displayed highest accuracy based on diffusion MRI, which besides demonstrated high correlation with clinical scores. +4 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-09
Neighborhood built environment associated with cognition and dementia risk among older adults: A systematic literature review
64/100 ✓ Peer-reviewed Risk factors Social science & medicine (1982)
Key finding: Cognitive impairment associated with aging is a serious and growing public health problem. +1 more finding
Full summary, score breakdown and related studies → Original source
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2021-11-08
Evaluation of Available Cognitive Tools Used to Measure Mild Cognitive Decline: A Scoping Review
50/100 ✓ Peer-reviewed Clinical safety Nutrients
Key finding: The Montreal Cognitive Assessment (MoCA, n = 15), the Mini-Mental State Examination (MMSE, n = 14) and the Clock Drawing Test (CDT, n = 4) were most frequently cited in the literature. +4 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-08
Multi-domain interventions for the prevention of dementia and cognitive decline
84/100 ✓ Peer-reviewed Prevention trials The Cochrane database of systematic reviews
Key finding: Data collection and analysis We initially screened search results using a 'crowdsourcing' method in which members of Cochrane's citizen science platform identify RCTs. +3 more findings
Full summary, score breakdown and related studies → Original source
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2021-11-08
Subjective Cognitive Decline: Level of Risk for Future Dementia and Mild Cognitive Impairment, a Meta-Analysis of Longitudinal Studies
63/100 ✓ Peer-reviewed Prevention and risk Neuropsychology review
Key finding: SCD was associated with increased risk of developing dementia (HR = 1.90, 95% CI 1.52-2.36; OR = 2.48, 95% CI 1.97-3.14) and MCI (HR = 1.73, 95% CI 1.18-2.52; OR = 1.83, 95% CI 1.56-2.16).
Full summary, score breakdown and related studies → Original source
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2021-11-07
Potential new therapeutic target for Alzheimer's disease: Glucagon-like peptide-1
41/100 ✓ Peer-reviewed Drug development The European journal of neuroscience
Key finding: Increasing evidence shows a close relationship between Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM). +2 more findings
Full summary, score breakdown and related studies → Original source
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