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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 9,726–9,750 of 27,380 studies, newest first · page 390 of 1096.

October 2021 25

  1. 2021-10-08

    Correlation between cardiovascular risk factors and cognitive decline

    ✓ Peer-reviewed Risk factors European heart journal supplements : journal of the European Society of Cardiology

    Key finding: In fact, a growing number of scientific evidence shows how chronic exposure over the course of life, starting from young adulthood, to various risk factors-arterial hypertension, diabetes mellitus, obesity, tobacco smoke, sleep disorders-contribute significantly to the development of cognitive decline and dementia in the course of senescence.

    Full summary, score breakdown and related studies → Original source

  2. 2021-10-08

    PM2.5 exposure in association with AD-related neuropathology and cognitive outcomes

    ✓ Peer-reviewed Risk factors Environmental pollution (Barking, Essex : 1987)

    Key finding: Particulate matter with a diameter of less than 2.5 μm or PM2.5 is recognized worldwide as a cause of public health problems, mainly associated with respiratory and cardiovascular diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-10-08

    Factors Associated With Family Caregiver Burden of Home-Dwelling Patients With Advanced Dementia

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: Younger family caregivers caring for clinically unstable patients with severe neuropsychiatric symptoms experienced greater burden without informal paid help. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-10-08

    Shingles, Zostavax vaccination and risk of developing dementia: a nested case-control study-results from the UK Biobank cohort

    ✓ Peer-reviewed Long-term cohort studies BMJ open

    Key finding: Data were drawn from the UK Biobank cohort study with a total of 228 223 participants with Hospital Episodes Statistics and primary care linkage health records. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-10-07

    Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia

    ✓ Peer-reviewed Brain scans and imaging Annals of clinical and translational neurology

    Key finding: In both cohorts, we observed that tau-PET standardized uptake value ratio in medial temporal lobes was associated with clinical dementia rating Sum of Boxes (CDR-SoB) scores independently of local amyloid-PET uptake (FWE corrected at p < 0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-10-07

    Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease

    ✓ Peer-reviewed TREM2 and immune genetics PloS one

    Key finding: Except for αSyn, the additional biomarkers did not differentiate PD and HC, and none showed longitudinal differences, but most markers predict cognitive decline in PD during follow-up. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-10-06

    Human neocortical expansion involves glutamatergic neuron diversification

    ✓ Peer-reviewed Genetics Nature

    Key finding: The neocortex is disproportionately expanded in human compared with mouse 1,2 , both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons that selectively make connections within the neocortex and with other telencephalic structures. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-10-05

    Racial and Ethnic Disparities in Excess Deaths During the COVID-19 Pandemic, March to December 2020

    ✓ Peer-reviewed Disparities Annals of internal medicine

    Key finding: An estimated 2.88 million deaths occurred between March and December 2020. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-10-04

    Rho Signaling in Synaptic Plasticity, Memory, and Brain Disorders

    ✓ Peer-reviewed Disease mechanisms Frontiers in cell and developmental biology

    Key finding: Memory impairments are associated with many brain disorders such as autism, Alzheimer's disease, and depression.

    Full summary, score breakdown and related studies → Original source

  10. 2021-10-04

    Aducanumab: evidence from clinical trial data and controversies

    ✓ Peer-reviewed Treatments Drugs in context

    Key finding: Alzheimer's disease (AD) is the most common cause for dementia worldwide. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-10-04

    Frontal white matter lesions in Alzheimer's disease are associated with both small vessel disease and AD-associated cortical pathology

    ✓ Peer-reviewed Clinical safety Acta neuropathologica

    Key finding: Cerebral white matter lesions (WML) encompass axonal loss and demyelination and are assumed to be associated with small vessel disease (SVD)-related ischaemia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-10-04

    The Association of Age at Diagnosis of Hypertension With Brain Structure and Incident Dementia in the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Hypertension (Dallas, Tex. : 1979)

    Full summary, score breakdown and related studies → Original source

  13. 2021-10-02

    Neurogranin and Neuronal Pentraxin Receptor as Synaptic Dysfunction Biomarkers in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Journal of clinical medicine

    Key finding: The CSF level of Ng was significantly higher, whereas the NPTXR was significantly lower in the AD patients than in cognitively healthy controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-10 month only

    Sleep disorders in Alzheimer's disease: the predictive roles and potential mechanisms

    ✓ Peer-reviewed Risk factors Neural regeneration research

    Key finding: Given that sleep disorders are encountered in other types of dementia and psychiatric conditions, sleep-related biomarkers to predict Alzheimer's disease need to have high specificity and sensitivity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-10 month only

    A Friend and a Foe: 50 Years of the Apolipoprotein E Research Trail

    ✓ Peer-reviewed Genetics The Israel Medical Association journal : IMAJ

    Key finding: ApoE is associated with triglyceride-rich lipoproteins and mediates the clearance of these lipoproteins from the plasma. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2021-10-01

    Oral health's inextricable connection to systemic health: Special populations bring to bear multimodal relationships and factors connecting periodontal disease to systemic diseases and conditions

    ✓ Peer-reviewed Prevention and risk Periodontology 2000

    Key finding: Specifically, periodontal disease has been associated with diabetes, metabolic syndrome, obesity, eating disorders, liver disease, cardiovascular disease, Alzheimer disease, rheumatoid arthritis, adverse pregnancy outcomes, and cancer.

    Full summary, score breakdown and related studies → Original source

  17. 2021-10-01

    Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing

    ✓ Peer-reviewed Cognitive tests and assessment Journal of clinical and experimental neuropsychology

    Key finding: Accordingly, older adults typically have better cognition in morning hours compared to evening hours. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-10-01

    Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: It is currently unclear whether plasma biomarkers can be used as independent prognostic tools to predict changes associated with early Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-10-01

    Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline

    ✓ Peer-reviewed Prevention trials European journal of public health

    Key finding: Transferring a lifestyle intervention from a trial-setting to real life requires knowledge about the factors that influence effective implementation.

    Full summary, score breakdown and related studies → Original source

  20. 2021-10-01

    Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities

    ✓ Peer-reviewed Long-term cohort studies Brain : a journal of neurology

    Key finding: While common variant association studies have revealed multiple genetic loci with an influence on their volume, the contribution of rare variants to the WMH burden in the general population remains largely unexplored. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021-10-01

    Accelerated Approval of Aducanumab: Where Do We Stand Now?

    ✓ Peer-reviewed Drug development The Annals of pharmacotherapy

    Key finding: Its path to approval has been highly scrutinized, with many experts arguing that the FDA's decision was premature. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-10-01

    Targeting TREM2 on tumor-associated macrophages enhances immunotherapy

    ✓ Peer-reviewed TREM2 and immune genetics Cell reports

    Key finding: We identify TREM2 + tumor-associated macrophages (TAMs) as being correlated with exhausted CD8 + tumor-infiltrating lymphocytes (TILs) in mouse syngeneic tumor models and human solid tumors of multiple histological types. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-10-01

    Alzheimer's disease profiled by fluid and imaging markers: tau PET best predicts cognitive decline

    ✓ Peer-reviewed Mild cognitive impairment Molecular psychiatry

    Key finding: While results for amyloid-β were similar using CSF or imaging, CSF and imaging results for tau and neurodegeneration were not interchangeable.

    Full summary, score breakdown and related studies → Original source

  24. 2021-10-01

    Early stages of tau pathology and its associations with functional connectivity, atrophy and memory

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: In Alzheimer's disease, post-mortem studies have shown that the first cortical site where neurofibrillary tangles appear is the transentorhinal region, a subregion within the medial temporal lobe that largely overlaps with Brodmann area 35, and the entorhinal cortex. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-10-01

    Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas

    ✓ Peer-reviewed Risk factors World psychiatry : official journal of the World Psychiatric Association (WPA)

    Key finding: Decades of research have revealed numerous risk factors for mental disorders beyond genetics, but their consistency and magnitude remain uncer-tain.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →