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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,851–15,875 of 27,380 studies, newest first · page 635 of 1096.

August 2016 25

  1. 2016-08-24

    Neuropsychological Benefits of Neuro-Exergaming for Older Adults: A Pilot Study of an Interactive Physical and Cognitive Exercise System (iPACES)

    ✓ Peer-reviewed Prevention trials Journal of aging and physical activity

    Key finding: This randomized pilot trial examined the feasibility and cognitive benefit for older adults (n = 30) of a single bout of neuro-exergaming (physical activity with cognitive training) using an interactive physical and cognitive exercise system (iPACES), compared with that of exergaming or neurogaming alone. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-08-24

    TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing

    ✓ Peer-reviewed Brain tissue and pathology Brain pathology (Zurich, Switzerland)

    Key finding: This scheme has not been applied to the assessment of TDP-43 pathology in dementia with Lewy bodies (DLB) and aged controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-08-24

    HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Journal of neuroinflammation

    Key finding: Our current studies indicate that thrombin and HMGB1 are causal proximate proinflammatory mediators of BBB dysfunction, while sTM levels may indicate BBB endothelial damage; HMGB1 and sRAGE might serve as clinical biomarkers for progression and/or therapeutic efficacy along the AD spectrum. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-08-23

    The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

    ✓ Peer-reviewed Disease mechanisms Neurochemical research

    Key finding: NMDAR may be associated with the development of schizophrenia and a range of other psychopathologies including neurodegenerative disorders, depression and dementias.

    Full summary, score breakdown and related studies → Original source

  5. 2016-08-23

    Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aβ42/Aβ40 ratio

    ✓ Peer-reviewed Biomarkers Cell discovery

    Key finding: Mutations in the amyloid precursor protein (APP) gene and the aberrant cleavage of APP by γ-secretase are associated with Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-08-22

    Inclusion/exclusion criteria in late life depression antidepressant efficacy trials

    ✓ Peer-reviewed Risk factors International journal of geriatric psychiatry

    Key finding: There were nine inclusion/exclusion criteria that were used in more than half of the late life depression AETs: minimum severity on a symptom severity scale (100.0%), significant suicidal ideation (77.8%), psychotic features during the current episode of depression or history of a psychotic disorder (94.4%), history of bipolar disorder (77.8%), diagnosis of alcohol or drug abuse or dependence (83.3%), presence of a comorbid nondepressive, nonsubstance use Axis I disorder (55.6%), episode duration too short (66.7%), and an insufficient score on a cognitive screen (88.3%) or the presence of a cognitive disorder (55.6%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-08-18

    Prevalence of Amyloid Positron Emission Tomographic Positivity in Poststroke Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging Stroke

    Key finding: Thirty-eight (68%) patients who consented to PET imaging had PS-MCI. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-08-17

    Alzheimer's drug-development pipeline: 2016

    ✓ Peer-reviewed Clinical trials Alzheimer's & dementia (New York, N. Y.)

    Key finding: There are currently 24 agents in 36 trials in phase III of AD drug development. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-08-17

    Populations and Interventions for Palliative and End-of-Life Care: A Systematic Review

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: Palliative care improves cancer, CHF, COPD, and dementia outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2016-08-16

    Differential association of left and right hippocampal volumes with verbal episodic and spatial memory in older adults

    ✓ Peer-reviewed Hippocampus size on brain scans Neuropsychologia

    Key finding: It is suggested that right and left hippocampi are affected differentially in healthy or pathologic aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-08-12

    What is important at the end of life for people with dementia? The views of people with dementia and their carers

    ✓ Peer-reviewed End-of-life care International journal of geriatric psychiatry

    Key finding: Our findings reveal several different views on what is important about end-of-life care for people with dementia; therefore, a 'one-size-fits-all' approach to care is unlikely to be most appropriate. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-08-11

    Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: Apolipoprotein E (apoE) is associated with lipoproteins in the cerebrospinal fluid (CSF). +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-08-11

    Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    ✓ Peer-reviewed Drug development Nature communications

    Key finding: These data suggest that fenamate NSAIDs could be repurposed as NLRP3 inflammasome inhibitors and Alzheimer's disease therapeutics.

    Full summary, score breakdown and related studies → Original source

  14. 2016-08-11

    Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial

    ✓ Peer-reviewed Mild cognitive impairment Lancet (London, England)

    Key finding: Because of the significant ramifications of falls, many interventions have been proposed, but few have aimed to prevent falls via an integrated approach targeting both motor and cognitive function. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2016-08-11

    Improving comfort in people with dementia and pneumonia: a cluster randomized trial

    ✓ Peer-reviewed Treatments BMC medicine

    Key finding: When compared to usual care, the practice guideline for optimal symptom relief did not relieve discomfort and symptoms in nursing home residents with dementia and pneumonia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2016-08-10

    A Decade of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Belgium

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Together, these biomarker data were the basis for several research papers, and significantly contributed to the validation of these biomarkers in autopsy-confirmed subjects.

    Full summary, score breakdown and related studies → Original source

  17. 2016-08-10

    Advance care planning for nursing home residents with dementia: Influence of 'we DECide' on policy and practice

    ✓ Peer-reviewed End-of-life care Patient education and counseling

    Key finding: 'We DECide' had a positive influence on advance care planning policy.

    Full summary, score breakdown and related studies → Original source

  18. 2016-08-10

    'Failure to Maintain': A theoretical proposition for a new quality indicator of nurse care rationing for complex older people in hospital

    ✓ Peer-reviewed Clinical safety International journal of nursing studies

    Key finding: This privileging, also known as implicit rationing, is theoretically and physiologically associated with a rise in the incidence of complications such as pressure injuries, pneumonia, urinary tract infection, and delirium. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2016-08-10

    Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease

    ✓ Peer-reviewed Lewy body dementia FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Efficient intercellular transfer of RNAs, proteins, and lipids as protected exosomal cargo has been demonstrated in the CNS, but distinct physiologic and pathologic roles have not been well defined for this pathway. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-08-09

    The Post-Anaesthesia N-acetylcysteine Cognitive Evaluation (PANACEA) trial: study protocol for a randomised controlled trial

    ✓ Peer-reviewed Inflammation and the immune system Trials

    Key finding: Some degree of cognitive decline after surgery occurs in as many as one quarter of elderly surgical patients, and this decline is associated with increased morbidity and mortality. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-08-09

    Mild cognitive impairment and risk of depression and anxiety: A population-based study

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Many people with mild cognitive impairment (MCI) suffer from concomitant depression or anxiety. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-08-09

    Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation

    ✓ Peer-reviewed TREM2 and immune genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: TREM2 is a lipid-sensing activating receptor on microglia known to be important for Alzheimer's disease (AD), but whether it plays a beneficial or detrimental role in disease pathogenesis is controversial. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-08-09

    Cognitive leisure activities and future risk of cognitive impairment and dementia: systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk International psychogeriatrics

    Key finding: Nineteen studies met our inclusion criteria and quality assessments. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2016-08-08

    Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease

    ✓ Peer-reviewed Mild cognitive impairment The Journal of Experimental Medicine

    Key finding: We demonstrate that injected α-syn fibrils recruit endogenous α-syn into pathological aggregates that spread transneuronally over several months, initially in the olfactory network and later in distant brain regions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2016-08-08

    TYROBP genetic variants in early-onset Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Exome sequencing was conducted on 45 EOAD patients with either a family history of Alzheimer's disease (AD, <65 years) or an extremely early age at the onset (≤55 years) followed by multiple variant filtering according to different modes of inheritance. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →