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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,351–8,375 of 27,380 studies, newest first · page 335 of 1096.

October 2022 25

  1. 2022-10-28

    Microbiome in Anxiety and Other Psychiatric Disorders

    ✓ Peer-reviewed Disease mechanisms The Medical clinics of North America

    Key finding: Initial studies suggested that the fluctuations in the quantity, variety, and composition of the gut microbiota can significantly affect disease processes.

  2. 2022-10-28

    Dysfunctional microglia and tau pathology in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Reviews in the neurosciences

    Key finding: Abnormalities in tau, Aβ, and microglial activation are frequently observed in dementia patients and indicate that these elements may work in concert to cause cognitive impairment. +1 more finding

  3. 2022-10-28

    Semiquantitative Approach to Amyloid Positron Emission Tomography Interpretation in Clinical Practice

    ✓ Peer-reviewed Brain scans and imaging World journal of nuclear medicine

    Key finding: Visual assessment and semiquantitative analysis provide highly congruent results, thereby enhancing reader confidence and improving scan interpretation. +4 more findings

  4. 2022-10-28

    Leveraging mHealth and Virtual Reality to Improve Cognition for Alzheimer's Patients: A Systematic Review

    ✓ Peer-reviewed Health systems and care delivery Healthcare (Basel, Switzerland)

    Key finding: Only three interventions reported either no improvements or no statistically significant improvements.

  5. 2022-10-28

    The Hong Kong Grocery Shopping Dialog Task (HK-GSDT): A Quick Screening Test for Neurocognitive Disorders

    ✓ Peer-reviewed Risk factors International journal of environmental research and public health

    Key finding: The results showed good reliability (i.e., internal consistency) and structural validity in the HK-GSDT. +1 more finding

  6. 2022-10-27

    Microglia and Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system International journal of molecular sciences

    Key finding: It is imperative to comprehend the intricate mechanisms that result in microglial impairment to develop new immunomodulating therapies that primarily attempt to recover the physiological role of microglia, allowing them to carry out their core function of brain protection.

  7. 2022-10-27
  8. 2022-10-26

    Air Pollution and Incidence of Dementia: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: A total of 20 studies were included in the systematic review, and 17 provided data for the meta-analysis. +4 more findings

  9. 2022-10-26

    Drug Delivery Systems as a Strategy to Improve the Efficacy of FDA-Approved Alzheimer's Drugs

    ✓ Peer-reviewed Treatments Pharmaceutics

    Key finding: As a result, the pharmacological therapeutic effectiveness is raised, while the unwanted side effects induced by the unspecific distribution decrease.

  10. 2022-10-26

    Magnetic Resonance Images Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction in Alzheimer Disease

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: ALPS-index may provide useful disease progression or treatment biomarkers for patients with AD as an indicator of modulation of glymphatic activity.

  11. 2022-10-25

    The use of psychological network analysis in informal dementia care: an empirical illustration

    ✓ Peer-reviewed Caregiving Aging & mental health

    Key finding: The analysis suggests a complex network of interacting variables. +4 more findings

  12. 2022-10-25

    198 A UNIQUE COMMUNITY POST-DIAGNOSTIC DEMENTIA SUPPORT SERVICE DELIVERED BY THE ADVANCED NURSE PRACTITIONER

    ✓ Peer-reviewed Risk factors Age and Ageing

    Key finding: Patient satisfaction outcomes range from 71 - 100% with service intervention outcomes favourably indicating the direct impact of the service, which are unmeasurable to the older adult living with dementia, and include increases in: (i) Confidence - 90%; (ii) Mood - 50% and (iii) open to talking through difficulties encountered - 87%. +2 more findings

  13. 2022-10-25

    Phosphorylated Tau in Alzheimer's Disease and Other Tauopathies

    ✓ Peer-reviewed Lewy body dementia International journal of molecular sciences

    Key finding: Tauopathies, including Pick's disease, frontotemporal dementia, corticobasal degeneration, Alzheimer's disease, argyrophilic grain disease, progressive supranuclear palsy, and Huntington's disease, are the result of misprocessing and accumulation of tau within the neuronal and glial cells.

  14. 2022-10-24

    Beneficial effects of natural flavonoids on neuroinflammation

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in immunology

    Key finding: Flavonoids, as a species of important natural compounds, have been widely revealed to alleviate neuroinflammation by inhibiting the production of pro-inflammatory mediators, elevating the secretion of anti-inflammatory factors, and modulating the polarization of microglia and astrocyte, mainly via suppressing the activation of NLRP3 inflammasome, as well as NF-κB, MAPK, and JAK/STAT pathways, promoting Nrf2, AMPK, BDNF/CREB, Wnt/β-Catenin, PI3k/Akt signals and SIRT1-mediated HMGB1 deacetylation.

  15. 2022-10-24

    New insight into neurological degeneration: Inflammatory cytokines and blood-brain barrier

    ✓ Peer-reviewed Costs and economics Frontiers in molecular neuroscience

    Key finding: Neurological degeneration after neuroinflammation, such as that resulting from Alzheimer's disease (AD), stroke, multiple sclerosis (MS), and post-traumatic brain injury (TBI), is typically associated with high mortality and morbidity and with permanent cognitive dysfunction, which places a heavy economic burden on families and society.

  16. 2022-10-24

    Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses

    ✓ Peer-reviewed Disease mechanisms Frontiers in pharmacology

    Key finding: Mounting evidence supports the significant role of Lactobacillus spp. and their components (such as metabolites, peptidoglycans, and/or surface proteins) in modulatingimmune responses, primarily through exchange of immunological signals between gastrointestinal tract and distant organs. +2 more findings

  17. 2022-10-23

    Sense of meaning and purpose in life and risk of incident dementia: New data and meta-analysis

    ✓ Peer-reviewed Long-term cohort studies Archives of gerontology and geriatrics

    Key finding: A greater sense of meaning and purpose in life is associated with lower dementia risk. +3 more findings

  18. 2022-10-22

    Interferon γ: a master cytokine in microglia-mediated neural network dysfunction and neurodegeneration

    ✓ Peer-reviewed Digital health tools Trends in neurosciences

    Key finding: Priming by IFN-γ results in proliferation (microgliosis), enhanced synapse elimination, and moderate nitric oxide release sufficient to impair synaptic transmission, gamma rhythm activity, and cognitive functions. +1 more finding

  19. 2022-10-21

    Genetically identical twins show comparable tau PET load and spatial distribution

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: Tau accumulation starts during the preclinical phase of Alzheimer's disease and is closely associated with cognitive decline. +4 more findings

  20. 2022-10-21

    APOE4 derived from astrocytes leads to blood-brain barrier impairment

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: We found that humanized APOE4, but not APOE2 or APOE3, mice show a leaky blood-brain barrier, increased MMP9, impaired tight junctions, and reduced astrocyte end-foot coverage of blood vessels.

  21. 2022-10-21

    Plasma neurofilament light as blood marker for poor brain white matter integrity among middle-aged urban adults

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: Multivariable-adjusted regression models, correcting for multiple-testing revealed that, overall, higher NfLv1 was associated with greater global TR (β ± SE: +0.0000560 ± 0.0000186, b = 0.27, p = 0.003, q = 0.012), left frontal WM TR (β ± SE: + 0.0000706 ± 0.0000201, b ± 0.30, p = 0.001, q = 0.0093) and right frontal WM TR (β ± SE: + 0.0000767 ± 0.000021, b ± 0.31, p < 0.001, q = 0.0093). +1 more finding

  22. 2022-10-21

    Vascular Considerations for Amyloid Immunotherapy

    ✓ Peer-reviewed Treatments Current neurology and neuroscience reports

    Key finding: Decades of research into anti-Aβ immunotherapies provide evidence for increased Aβ clearance from the brain; however, this is frequently accompanied by complicated vascular deficits. +4 more findings

  23. 2022-10-21

    Interdisciplinary Aging Research to Address Health Disparities in Alzheimer’s Disease and Related Dementias: A Scientific Training Program for Early-Career Scholars

    ✓ Peer-reviewed Health systems and care delivery The Journals of Gerontology Series B

    Key finding: According to the National Institute on Aging (NIA), there are more than 70 associated genes or genetic areas associated with Alzheimer’s when 20 years ago, we knew of only four (Hodes, 2022). +4 more findings

  24. 2022-10-20

    Acetylcholinesterase Inhibitory Activities of Essential Oils from Vietnamese Traditional Medicinal Plants

    ✓ Peer-reviewed Risk factors Molecules

    Key finding: The results obtained suggest that these essential oils may be used to control mosquito vectors that transmit pathogenic viruses or to support the treatment of Alzheimer’s disease.

  25. 2022-10-20

    Development and clinical validation of CT-based regional modified Centiloid method for amyloid PET

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: Both MRI-based and CT-based rdcCL scales showed that FMM and FBB were highly correlated with each other, globally and regionally (R2 = 0.96~0.99). +4 more findings

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