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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 9,251–9,275 of 27,380 studies, newest first · page 371 of 1096.

February 2022 17

  1. 2022-02-02

    GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study

    ✓ Peer-reviewed Cognitive tests and assessment Movement disorders : official journal of the Movement Disorder Society

    Key finding: Common genetic variance in apolipoprotein E (APOE), β-glucocerebrosidase (GBA), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) has been linked to cognitive decline in Parkinson's disease (PD), although studies have yielded mixed results. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-02-02

    Dysfunction of the blood-brain barrier in Alzheimer's disease: Evidence from human studies

    ✓ Peer-reviewed Genetics Neuropathology and applied neurobiology

    Key finding: Improved insight into these pathomechanisms may allow to shed light on the role of Aβ deposition as a primary versus a secondary event in the complex pathogenesis of AD.

    Full summary, score breakdown and related studies → Original source

  3. 2022-02-02

    Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis

    ✓ Peer-reviewed Biomarkers Molecular neurodegeneration

    Key finding: This study reveals an important role of astrocytic apoE3 and apoE4 on the deposition and accumulation of Aβ plaques as well as on certain Aβ-associated downstream effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2022-02-01

    Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's Disease

    Key finding: Increased p-tau181 was observed for both ɛ4 carriers and non-carriers close to AD onset, but exclusively for ɛ4 carriers in the early preclinical groups (7- and 13-years pre-AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-02 month only

    The relationship between social isolation and anxiety in people with cognitive impairment in the United States

    ✓ Peer-reviewed Risk factors International journal of geriatric psychiatry

    Key finding: We observed that greater social isolation was related to increased anxiety in people with cognitive impairment (coefficients = 0.7242, t = 2.51, p = 0.015), adjusting for severity of cognitive impairment, race, pain, depression, activities of daily living, and instrumental activities of daily living. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-02 month only

    A Brewed Awakening: Neuropsychiatric Effects of Caffeine in Older Adults

    ✓ Peer-reviewed Risk factors Clinics in geriatric medicine

    Key finding: Caffeine use is prevalent among older adults; thus, providers need to be aware of the prevalence and diagnostic criteria of caffeine use disorder versus nonproblematic use.

    Full summary, score breakdown and related studies → Original source

  7. 2022-02-01

    Assessment of hearing and vision impairment in cohort studies collecting cognitive data in older adults

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Investigators/staff from 85 (of 192 cohorts) responded; 6 (7%) excluded participants with severe impairment; 80 (94%) measured hearing and/or vision impairment, while 5 (6%) measured neither. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-02-01

    Personalised treatment for cognitive impairment in dementia: development and validation of an artificial intelligence model

    ✓ Peer-reviewed Treatments BMC medicine

    Key finding: Overall, 1343 patients with MMSE scores were identified for internal validation and 285 [21.22%] took the drug recommended. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2022-02-01

    Variant TREM2 Signaling in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of molecular biology

    Key finding: Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is an important receptor that is crucial to the functioning of microglial cells, and variants of this protein have been found to be associated with a significantly increased risk of Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2022-02-01

    Hippocampus and its involvement in Alzheimer's disease: a review

    ✓ Peer-reviewed Prevention trials 3 Biotech

    Key finding: Hippocampus is the significant component of the limbic lobe, which is further subdivided into the dentate gyrus and parts of Cornu Ammonis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2022-02-01

    Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Alzheimer's research & therapy

    Key finding: Our results indicate that glycosphingolipids regulated by GCS are important modulators of Aβ neuropathology and that glycosphingolipid homeostasis plays a critical role in the consolidation of remote memories. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-02-01

    Short-Term Impacts of COVID-19 Public Health Regulation on Consumer Food Purchases: A Case Study From a Grocery Store in Montana

    ✓ Peer-reviewed Risk factors Frontiers in Sustainable Food Systems

    Key finding: Overall, we found that consumers increased purchases in most food groups during the pandemic, including nutrient-dense and energy-dense products, most outstandingly for starchy vegetables, legumes, and convenience food. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2022-02-01

    Toward ‘net zero’ hysterectomy for Australia; New Zealand is already heading there…

    ✓ Peer-reviewed Risk factors Australian and New Zealand Journal of Obstetrics and Gynaecology

    Key finding: Hysterectomy is often recommended for gynaecological symptomatology because menstruation inevitably ceases, and the mortality rate associated with this operation is low3. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2022-02-01

    Soluble TREM2 inhibits secondary nucleation of Aβ fibrillization and enhances cellular uptake of fibrillar Aβ

    ✓ Peer-reviewed TREM2 and immune genetics Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Mutations in TREM2 have been linked to increased risk of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-02-01

    Preeclampsia and eclampsia: the conceptual evolution of a syndrome

    ✓ Peer-reviewed Prevention and risk American journal of obstetrics and gynecology

    Key finding: We review the epidemiologic data that led to the recommendation to use diastolic hypertension and proteinuria as diagnostic criteria, as their combined presence was associated with an increased risk of fetal death and the birth of small-for-gestational-age neonates. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2022-02-01

    Vasculocentric Axonal NfH in Small Vessel Disease

    ✓ Peer-reviewed Biomarkers Journal of neuropathology and experimental neurology

    Key finding: We conclude that axonal pNfH is a feature of subcortical white matter in aged brains.

    Full summary, score breakdown and related studies → Original source

  17. 2022-02-01

    Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Of 343 participants, the mean (SD) age was 72.56 (7.24) years, and 157 (51.1%) were female.

    Full summary, score breakdown and related studies → Original source

January 2022 8

  1. 2022-01-31

    Short sleep duration and dementia: a narrative review

    ✓ Peer-reviewed Risk factors Proceedings (Baylor University. Medical Center)

    Key finding: Still, current evidence for this relationship is conflicting. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-01-31

    Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration

    ✓ Peer-reviewed Vascular contributions Circulation

    Key finding: The mitigating role of oral anticoagulation in specific subgroups (eg, low stroke risk, short duration or silent AF, after successful AF ablation, or atrial cardiopathy) and the effect of rhythm versus rate control strategies remain unknown.

    Full summary, score breakdown and related studies → Original source

  3. 2022-01-31

    Association between single moderate to severe traumatic brain injury and long-term tauopathy in humans and preclinical animal models: a systematic narrative review of the literature

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica communications

    Key finding: Of 4,150 studies screened, 26 were eligible for inclusion, of which 17 were human studies, 8 were preclinical animal studies, and 1 included both human and preclinical animal studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2022-01-31

    Gut Microbiota Composition Is Related to AD Pathology

    ✓ Peer-reviewed Digital health tools Frontiers in immunology

    Key finding: Gut microbiota composition was associated with amyloid and p-tau status. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-01-30

    Aducanumab, a Novel Anti-Amyloid Monoclonal Antibody, for the Treatment of Alzheimer's Disease: A Comprehensive Review

    ✓ Peer-reviewed Treatments Health psychology research

    Key finding: However, there is concern the magnitude of this drug's benefit may only be statistically significant and not clinically significant. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2022-01-30

    FOOD-BASED AND NON-FOOD-BASED INTERVENTIONS TO IMPROVE DIETARY DIVERSITY: A LITERATURE REVIEW

    ✓ Peer-reviewed Risk factors Media Gizi Indonesia

    Key finding: Poor dietary diversity is associated with malnutrition, stunting, poor gut health, pregnancy complications, and cognitive impairment.

    Full summary, score breakdown and related studies → Original source

  7. 2022-01-29

    The interplay between oxidative stress and autophagy: focus on the development of neurological diseases

    ✓ Peer-reviewed Disease mechanisms Behavioral and brain functions : BBF

    Key finding: Remarkably, oxidative stress prompted by an increase of ROS threatens cerebral integrity and improves the severity of other pathogenic agents such as mitochondrial damage in neuronal disturbances. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-01-28

    Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1

    ✓ Peer-reviewed Genetics BMC genomics

    Key finding: Using the data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), we performed a genome-wide association study (GWAS) between 565,373 single nucleotide polymorphisms (SNPs) and 16 key AD biomarkers from 1,576 subjects at four visits. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →