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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,501–10,525 of 27,380 studies, newest first · page 421 of 1096.

February 2021 25

  1. 2021-02-23

    Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia

    ✓ Peer-reviewed Biomarkers Neurobiology of disease

    Key finding: NfL levels were significantly higher in SCAs than controls at both time points (p < 0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-02-23

    Melatonin levels in the Alzheimer's disease continuum: a systematic review

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Our systematic review shows evidence for disruptions in (night-time) melatonin levels in AD as compared to age-matched controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-02-23

    Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology

    ✓ Peer-reviewed Digital health tools Acta neuropathologica communications

    Key finding: Frontotemporal lobar degeneration proteinopathies with tau inclusions (FTLD-Tau) or TDP-43 inclusions (FTLD-TDP) are associated with clinically similar phenotypes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-02-23

    Susceptibility-weighted Imaging: Technical Essentials and Clinical Neurologic Applications

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: SWI is an MRI sequence sensitive to compounds that distort the local magnetic field (eg, calcium and iron), in which the phase information can differentiate. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-02-23

    Randomized crossover trial of a modified ketogenic diet in Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Alzheimer's research & therapy

    Key finding: This is the first randomized trial to investigate the impact of a ketogenic diet in patients with uniform diagnoses of AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-02-23

    Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)

    ✓ Peer-reviewed Biomarkers Autophagy

    Key finding: In this study, we demonstrated the cognitive-enhancing effect of three-needle EA (TNEA) in an animal model of AD with beta-amyloid (Aβ) pathology (5xFAD).

    Full summary, score breakdown and related studies → Original source

  7. 2021-02-22

    Ethical Aspects of Artificially Administered Nutrition and Hydration: An ASPEN Position Paper

    ✓ Peer-reviewed End-of-life care Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    Key finding: These discussions should be guided by the 4 ethical principles. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-02-22

    Mediterranean Diet and Risk of Dementia and Alzheimer's Disease in the EPIC-Spain Dementia Cohort Study

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: The Mediterranean diet (MD) has shown to reduce the occurrence of several chronic diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-02-22

    Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Vascular cognitive impairment (VCI) describes a broad spectrum of cognitive impairments caused by cerebrovascular disease, ranging from mild cognitive impairment to dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-02-21

    Crosstalk between Gut and Brain in Alzheimer's Disease: The Role of Gut Microbiota Modulation Strategies

    ✓ Peer-reviewed Inflammation and the immune system Nutrients

    Key finding: Studies suggest that the GM can influence the health of the host, and several factors can modify the GM composition, such as diet, drug intake, lifestyle, and geographical locations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2021-02-20

    A Structured Brain-wide and Genome-wide Association Study Using ADNI PET Images

    ✓ Peer-reviewed Genetics The Canadian journal of statistics = Revue canadienne de statistique

    Key finding: Compared to conventional single-voxel-to-single-SNP approaches, our approach is more efficient and powerful in selecting the important signals by integrating anatomic and gene grouping structures in the brain and the genome, respectively. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-02-20

    Imaging Techniques in Alzheimer's Disease: A Review of Applications in Early Diagnosis and Longitudinal Monitoring

    ✓ Peer-reviewed Hippocampus size on brain scans International journal of molecular sciences

    Key finding: Reduced hippocampal volume is a biomarker for neurodegeneration, but atrophy is not an AD-specific measure.

    Full summary, score breakdown and related studies → Original source

  13. 2021-02-20

    Safety Recommendations for Grocery Store Workers and Employers during the COVID-19 Pandemic

    ✓ Peer-reviewed Risk factors Food Science and Nutrition

    Key finding: Grocery stores are vital to the health and well-being of American citizens. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-02-20

    Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: Microglia, the tissue-resident macrophages of the central nervous system (CNS), are important for CNS homeostasis and implicated in AD pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-02-20

    Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroscience research

    Key finding: The underlying cellular processes that promote this activation remain unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-02-19

    A genome-wide association study in human lymphoblastoid cells supports safety of mitochondrial complex I inhibitor

    ✓ Peer-reviewed Genetics Mitochondrion

    Key finding: Earlier, we demonstrated that mild mitochondrial complex I inhibitor CP2 blocks neurodegeneration and cognitive decline in multiple mouse models of AD.

    Full summary, score breakdown and related studies → Original source

  17. 2021-02-19

    Moving fluid biomarkers for Alzheimer's disease from research tools to routine clinical diagnostics

    ✓ Peer-reviewed Biomarkers Molecular neurodegeneration

    Key finding: Four fluid-based biomarkers have been developed into diagnostic tests for Alzheimer's disease (AD) pathology: the ratio of 42 to 40 amino acid-long amyloid β, a marker of plaque pathology; total-tau and phosphorylated tau, markers of AD-related changes in tau metabolism and secretion; and neurofilament light, a marker of neurodegeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-02-19

    Survival in hospice patients with dementia: the effect of home hospice and nurse visits

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Nearly 40% of patients with dementia in our study experienced live discharge or a long length of stay. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-02-19

    Data-driven FDG-PET subtypes of Alzheimer's disease-related neurodegeneration

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's research & therapy

    Key finding: Previous research has described distinct subtypes of Alzheimer's disease (AD) based on the differences in regional patterns of brain atrophy on MRI. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-02-19

    Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components

    ✓ Peer-reviewed Biomarkers Frontiers in aging neuroscience

    Key finding: Surprisingly, cultured 3xTg-AD astrocytes showed increased glial fibrillary acidic protein (GFAP) reactivity compared to PS1-KI astrocytes, which denotes astrocytic hyperreactivity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-02-18

    The Forgotten Psychopathology of Depressed Long-Term Care Facility Residents: A Call for Evidence-Based Practice

    ✓ Peer-reviewed Health systems and care delivery Dementia and geriatric cognitive disorders extra

    Key finding: We had 38,777 and 40,277 hits for depression and dementia, respectively, in long-term care facilities or nursing homes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-02-18

    The Neurovascular Unit Dysfunction in Alzheimer's Disease

    ✓ Peer-reviewed Vascular contributions International journal of molecular sciences

    Key finding: According to the vascular hypothesis of AD, vascular risk factors can result in dysregulation of the neurovascular unit (NVU) and hypoxia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-02-18

    Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination

    ✓ Peer-reviewed TREM2 and immune genetics Nature metabolism

    Key finding: Yet, the limiting factors responsible for poor CNS repair are only partially understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-02-18

    Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia

    ✓ Peer-reviewed TREM2 and immune genetics Nature neuroscience

    Key finding: It is therefore important to identify and neutralize the mechanisms that promote neurodegeneration in MS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-02-18

    White matter aging drives microglial diversity

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: Using single-cell RNA sequencing from white and gray matter separately, we identified white matter-associated microglia (WAMs), which share parts of the disease-associated microglia (DAM) gene signature and are characterized by activation of genes implicated in phagocytic activity and lipid metabolism. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →