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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,626–8,650 of 27,380 studies, newest first · page 346 of 1096.

August 2022 6

  1. 2022-08-01

    The Link between Obstructive Sleep Apnea and Neurocognitive Impairment: An Official American Thoracic Society Workshop Report

    ✓ Peer-reviewed Disparities Annals of the American Thoracic Society

    Key finding: An American Thoracic Society workshop was convened that included clinicians, basic scientists, and epidemiologists with expertise in OSA, cognition, and dementia, with the overall objectives of summarizing the state of knowledge in the field, identifying important research gaps, and identifying potential directions for future research. +1 more finding

  2. 2022-08-01

    Worldwide prevalence of mild cognitive impairment among community dwellers aged 50 years and older: a meta-analysis and systematic review of epidemiology studies

    ✓ Peer-reviewed Prevention and risk Age and ageing

    Key finding: The global prevalence of MCI among community dwellers is over 15% and is affected by age, gender, education level and region of study sites. +3 more findings

  3. 2022-08-01
  4. 2022-08-01

    Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: In participants with prodromal to mild AD in this randomized clinical trial, semorinemab did not slow clinical AD progression compared with placebo throughout the 73-week study period but did demonstrate an acceptable and well-tolerated safety profile. +2 more findings

  5. 2022-08-01

    β-Amyloid-Dependent and -Independent Genetic Pathways Regulating CSF Tau Biomarkers in Alzheimer Disease

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Genetic pathways implicated in causing AD are related to altered levels of soluble tau through both Aβ-dependent and Aβ-independent mechanisms, which may have relevance for anti-tau drug development. +2 more findings

  6. 2022-08-01

    Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Among 300 participants with DS and a control group of 37 non-DS siblings, mean (SD) age was 45.0 (10.1) years, and 167 (49.6%) were men. +3 more findings

July 2022 19

  1. 2022-07-31

    Comparative study of rivastigmine and galantamine on the transgenic Drosophila model of Alzheimer's disease

    ✓ Peer-reviewed Treatments Current research in pharmacology and drug discovery

    Key finding: Alzheimer's Disease (AD) is characterized as a progressive neurodegenerative disease most commonly associated with memory deficits and cognitive decline. +3 more findings

  2. 2022-07-31

    The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer s & Dementia

    Blood-based markers (BBMs) have recently shown promise to revolutionize the diagnostic and prognostic work-up of Alzheimer's disease (AD), as well as to improve the design of interventional trials.

  3. 2022-07-30

    The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction

    ✓ Peer-reviewed Disease mechanisms Seminars in cell & developmental biology

    Key finding: While AD is a multifactorial disease, synaptic dysfunction is one of the major neuropathological changes that occur early in AD, before clinical symptoms appear, and is associated with the progression of cognitive deterioration. +1 more finding

  4. 2022-07-29

    Clinical impact of whole-genome sequencing in patients with early-onset dementia

    ✓ Peer-reviewed Genetics Journal of neurology, neurosurgery, and psychiatry

    Key finding: Clinical genetic diagnosis was achieved in 7 of 50 (14%) of the patients, with a further 8 patients (16%) found to have established risk factors which may have contributed to their EOD. +4 more findings

  5. 2022-07-29

    Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in immunology

    Key finding: Accumulating evidence attests to the important roles of the immune system in OA pathogenesis. +3 more findings

  6. 2022-07-28

    Impact of a multidomain lifestyle intervention on regional spontaneous brain activity

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: ReHo values from regions with significant longitudinal changes were compared between the intervention and control groups and their correlations with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) or serum brain-derived neurotrophic factor (BDNF) were evaluated. +1 more finding

  7. 2022-07-28

    Longitudinal associations of pain and cognitive decline in community-dwelling older adults

    ✓ Peer-reviewed Prevention trials Psychology and aging

    Key finding: Pain is inversely associated with cognitive function in older adults, but the effects of pain on cognitive decline are not fully clear.

  8. 2022-07-28
  9. 2022-07-27

    Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects-a MissionAD tau sub-study

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: Percentage of visually tau-positive scans increased with amyloid-beta deposition measured in 18F-florbetaben Centiloids (CL) (7.7% (<36 CL), 80% (>83 CL)). 18F-PI-2620 standardized uptake value ratio (SUVR) was correlated with increased 18F-florbetaben CL in several regions of interest. +4 more findings

  10. 2022-07-27

    Physical and Mental Activity, Disease Susceptibility, and Risk of Dementia: A Prospective Cohort Study Based on UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: The association between patterns of physical/mental activity and dementia and how it is affected by disease susceptibility remains unknown. +3 more findings

  11. 2022-07-27

    Association of Ultraprocessed Food Consumption With Risk of Dementia: A Prospective Cohort Study

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: In this prospective cohort study, higher consumption of UPF was associated with higher risk of dementia, whereas substituting unprocessed or minimally processed foods for UPF was associated with lower risk of dementia. +4 more findings

  12. 2022-07-26

    Effect of simultaneous exercise and cognitive training on executive functions, baroreflex sensitivity, and pre-frontal cortex oxygenation in healthy older adults: a pilot study

    ✓ Peer-reviewed Prevention trials GeroScience

    Key finding: The superiority of simultaneous training compared to passive control and physical training alone seems clear but very few studies compared simultaneous training to cognitive training alone. +2 more findings

  13. 2022-07-25

    Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease

    ✓ Peer-reviewed Genetics Neuron

    Key finding: Tau aggregation in neurofibrillary tangles (NFTs) is closely associated with neurodegeneration and cognitive decline in Alzheimer's disease (AD). +1 more finding

  14. 2022-07-25
  15. 2022-07-25

    Lexical and Acoustic Speech Features Relating to Alzheimer Disease Pathology

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: We compared digital speech and language features of patients with amnestic Alzheimer disease (aAD) or logopenic variant primary progressive aphasia (lvPPA) in a biologically confirmed cohort and related these features to neuropsychiatric test scores and CSF analytes. +3 more findings

  16. 2022-07-24

    Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: Higher plasma NfL and Aβ42/40 ratio were associated with cerebrovascular neuropathologic scales (p < 0.05) but not with Braak stage, neuritic plaque score, or Thal phase. +1 more finding

  17. 2022-07-22
  18. 2022-07-22
  19. 2022-07-22

    TREM2 macrophages induced by human lipids drive inflammation in acne lesions

    ✓ Peer-reviewed TREM2 and immune genetics Science immunology

    Key finding: The disease involves excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes , and a host inflammatory response with foamy macrophages. +3 more findings

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