Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 3,101–3,125 of 27,380 studies, newest first · page 125 of 1096.
September 2025 25
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2025-09-27
Particulate air pollution from different emission sources, cognitive performance, and cognitive declines in India
70/100 ✓ Peer-reviewed Risk factors Environment international
Key finding: Among 5,699 participants (mean age: 70±8 years), we observed total PM2.5 concentrations ranging from 16 to 206 μg/m3. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-27
FDG-PET brain glucose hypometabolism predicts Alzheimer's disease progression pathways in cognitively normal adults: A longitudinal competing risks modeling
61/100 ✓ Peer-reviewed Mild cognitive impairment Metabolism Open
Key finding: Four progression pathways were concluded from our analyses, cognitive stability (32.8 %), sequential MCI-only decline (34.9 %), accelerated MCI-to-dementia progression (15.8 %), and rapid direct conversion (16.5 %). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-27
Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework
49/100 ✓ Peer-reviewed Prevention and risk EBioMedicine
Key finding: Our analysis suggests that incorporating these four additional factors could potentially increase the proportion of preventable dementia cases to about 65%. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-27
Red blood cell ω-3 status and longitudinal cognition in individuals at risk of Alzheimer disease
51/100 ✓ Peer-reviewed Genetics Journal of Nutrition
Key finding: RBC DHA was associated with a positive (improved) global cognition (PACC) rate of change (estimate: 0.011; 95% CI: 0.001, 0.021; P = 0.024). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-27
Associations of alcohol drinking with incident dementia: a prospective study from the UK Biobank
52/100 ✓ Peer-reviewed Prevention and risk European Journal of Epidemiology
Key finding: Compared to non-drinking, low-moderate drinking reduced dementia risk (HR, 0.65; 95% CI, 0.59-0.73), while heavy drinking showed no significant association (HR, 0.88; 95% CI, 0.75-1.02). +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-26
Alzheimer's Disease: From Molecular Mechanisms to Promising Therapeutic Strategies
43/100 ✓ Peer-reviewed Disease mechanisms International journal of molecular sciences
Key finding: Significant financial and research resources have been invested into studying the pathology of AD.
Full summary, score breakdown and related studies → Original source
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2025-09-26
Mapping cerebrospinal fluid biomarkers to dementia risk through Mendelian randomization
43/100 ✓ Peer-reviewed Tau biomarkers Medicine
Key finding: Specific CSF biomarker patterns may be associated with different types of dementia.
Full summary, score breakdown and related studies → Original source
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2025-09-26
Adhering to Healthy Dietary Patterns Prevents Cognitive Decline of Older Adults with Sarcopenia: The Mr. OS and Ms. OS Study
51/100 ✓ Peer-reviewed Prevention trials Nutrients
Key finding: Sarcopenia and its components were associated with baseline MMSE and MMSE changes. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-26
Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage
39/100 ✓ Peer-reviewed Disease mechanisms Molecular Psychiatry
Key finding: Disturbances in the synaptic function can also be associated with the C9orf72 repeat expansion (C9-HRE), the most common genetic mutation causing FTD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-26
Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner
39/100 ✓ Peer-reviewed Inflammation and the immune system Journal of Neuroinflammation
Key finding: Obesity is associated with numerous adverse neural effects, including reduced neurogenesis, cognitive impairment, and increased risks for developing Alzheimer's disease (AD) and vascular dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-26
Diabetic retinopathy as the primary predictor of mild cognitive impairment in type 2 diabetes: Insights from machine learning models
51/100 ✓ Peer-reviewed Mild cognitive impairment PLoS ONE
Key finding: Mild cognitive impairment (MCI) is a significant and increasingly recognized problem in individuals with type 2 diabetes mellitus (T2DM). +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-26
Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies
46/100 ✓ Peer-reviewed Lewy body dementia Nature Communications
Key finding: Immunohistochemistry and electron microscopy validate these findings. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-25
Association between the Frequency of Individual Outdoor Activity and Risk of Incident Dementia in an Elderly Population in China: A National Cohort Study
49/100 ✓ Peer-reviewed Cognitive tests and assessment Neuroepidemiology
Key finding: Over a median follow-up period of 4.33 years, 637 participants (7.27%) developed dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-25
Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study
44/100 ✓ Peer-reviewed Risk factors Frontiers in Aging Neuroscience
Key finding: Cerebrovascular disease (OR: 2.39, 95% CI: 1.44-3.97) and peripheral arterial disease (OR: 1.74, 95% CI: 1.03-2.95) were significant risk factors, while higher education (OR 0.85, 95% CI 0.76-0.94) and later diabetes onset (OR: 0.93, 95% CI: 0.88-0.98) were protective. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-25
Harnessing the Power of Technology to Transform Delirium Severity Measurement in the Intensive Care Unit: Protocol for a Prospective Cohort Study
54/100 ✓ Peer-reviewed Treatments JMIR research protocols
Key finding: We are currently in the recruitment and data collection phase.
Full summary, score breakdown and related studies → Original source
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2025-09-24
Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program
50/100 ✓ Peer-reviewed Disparities Communications biology
Key finding: We report significant negative associations (P < 0.002) of the cross-population (P = 1.3 × 10-5) and European (PEA = 3.0 × 10-8) fasting insulin PSs with total cranial volume, and of a metabolic syndrome European PS with general cognitive function (BEA = -0.13, PEA = 0.0002) and lateral ventricular volume (BEA = 0.09, PEA = 0.002). +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-24
RNF168 dephosphorylation ameliorates cognitive decline in Aβ-based mouse models of Alzheimer's disease
43/100 ✓ Peer-reviewed Disease mechanisms Acta neuropathologica communications
Key finding: Our previous study demonstrated that growth signals regulate genomic stability through RNF168 phosphorylation. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-24
Hearing All About Donepezil: Its Role in the Field of Auditory Processing
48/100 ✓ Peer-reviewed Risk factors Cureus
Key finding: Her significant history of hearing loss with auditory hallucination impressively responded to the initiation of donepezil.
Full summary, score breakdown and related studies → Original source
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2025-09-24
Brain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention
80/100 ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease
Key finding: Clusters with diffuse or frontal-predominant cortical thinning, but with more favourable vascular profiles, characterized by lower blood pressure and reduced obesity, showed significantly less cortical thinning (mean thickness, AD-signature, and resilience-signature regions; all p < 0.05) following the intervention. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-24
Effects of triptolide herb on the progression of Alzheimer's disease preclinical models: a systematic review
42/100 ✓ Peer-reviewed Disease mechanisms Neurodegenerative disease management
Key finding: Tri demonstrates significant multi-target neuroprotective effects in AD preclinical models. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-24
‘It should be my choice’: voluntary assisted dying needs and preferences of Australians living with dementia
33/100 ✓ Peer-reviewed End-of-life care Ageing and Society
Key finding: Voluntary assisted dying (VAD) is an end-of-life care option available to eligible Australians living with a terminal condition, though people living with dementia are typically ineligible to choose VAD as part of their end-of-life care. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-24
The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer’s disease
63/100 ✓ Peer-reviewed Prevention trials Scientific Reports
Key finding: Dietary interventions, particularly the Mediterranean (MeDi) and MIND diets, have been associated with reduced cognitive decline, but their long-term comparative effects remain underexplored. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-24
Gait characteristics and factors associated with fall risk in patients with dementia with Lewy bodies
46/100 ✓ Peer-reviewed Cognitive tests and assessment Frontiers in Neurology
Key finding: Gait abnormalities are associated with cognitive decline, and reduced gait speed and gait asymmetry are markers of cognitive decline and increased fall risk in patients with established DLB. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-24
Machine learning and data-driven inverse modeling of metabolomics unveil key processes of active aging
36/100 ✓ Peer-reviewed Digital health tools npj Systems Biology and Applications
Key finding: Routine blood tests confirmed significant differences in AST and ALT.
Full summary, score breakdown and related studies → Original source
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2025-09-24
Empowering community health workers in dementia care in South Texas
34/100 ✓ Peer-reviewed Disparities Journal of Alzheimer s Disease
Key finding: Alzheimer's disease and related dementias disproportionately affect minority racial and ethnic communities. +1 more finding
Full summary, score breakdown and related studies → Original source
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