Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 3,101–3,125 of 27,380 studies, newest first · page 125 of 1096.

September 2025 25

  1. 2025-09-27

    Particulate air pollution from different emission sources, cognitive performance, and cognitive declines in India

    ✓ Peer-reviewed Risk factors Environment international

    Key finding: Among 5,699 participants (mean age: 70±8 years), we observed total PM2.5 concentrations ranging from 16 to 206 μg/m3. +4 more findings

  2. 2025-09-27

    FDG-PET brain glucose hypometabolism predicts Alzheimer's disease progression pathways in cognitively normal adults: A longitudinal competing risks modeling

    ✓ Peer-reviewed Mild cognitive impairment Metabolism Open

    Key finding: Four progression pathways were concluded from our analyses, cognitive stability (32.8 %), sequential MCI-only decline (34.9 %), accelerated MCI-to-dementia progression (15.8 %), and rapid direct conversion (16.5 %). +4 more findings

  3. 2025-09-27

    Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework

    ✓ Peer-reviewed Prevention and risk EBioMedicine

    Key finding: Our analysis suggests that incorporating these four additional factors could potentially increase the proportion of preventable dementia cases to about 65%. +1 more finding

  4. 2025-09-27

    Red blood cell ω-3 status and longitudinal cognition in individuals at risk of Alzheimer disease

    ✓ Peer-reviewed Genetics Journal of Nutrition

    Key finding: RBC DHA was associated with a positive (improved) global cognition (PACC) rate of change (estimate: 0.011; 95% CI: 0.001, 0.021; P = 0.024). +4 more findings

  5. 2025-09-27

    Associations of alcohol drinking with incident dementia: a prospective study from the UK Biobank

    ✓ Peer-reviewed Prevention and risk European Journal of Epidemiology

    Key finding: Compared to non-drinking, low-moderate drinking reduced dementia risk (HR, 0.65; 95% CI, 0.59-0.73), while heavy drinking showed no significant association (HR, 0.88; 95% CI, 0.75-1.02). +1 more finding

  6. 2025-09-26

    Alzheimer's Disease: From Molecular Mechanisms to Promising Therapeutic Strategies

    ✓ Peer-reviewed Disease mechanisms International journal of molecular sciences

    Key finding: Significant financial and research resources have been invested into studying the pathology of AD.

  7. 2025-09-26

    Mapping cerebrospinal fluid biomarkers to dementia risk through Mendelian randomization

    ✓ Peer-reviewed Tau biomarkers Medicine

    Key finding: Specific CSF biomarker patterns may be associated with different types of dementia.

  8. 2025-09-26
  9. 2025-09-26

    Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage

    ✓ Peer-reviewed Disease mechanisms Molecular Psychiatry

    Key finding: Disturbances in the synaptic function can also be associated with the C9orf72 repeat expansion (C9-HRE), the most common genetic mutation causing FTD. +4 more findings

  10. 2025-09-26

    Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner

    ✓ Peer-reviewed Inflammation and the immune system Journal of Neuroinflammation

    Key finding: Obesity is associated with numerous adverse neural effects, including reduced neurogenesis, cognitive impairment, and increased risks for developing Alzheimer's disease (AD) and vascular dementia. +4 more findings

  11. 2025-09-26

    Diabetic retinopathy as the primary predictor of mild cognitive impairment in type 2 diabetes: Insights from machine learning models

    ✓ Peer-reviewed Mild cognitive impairment PLoS ONE

    Key finding: Mild cognitive impairment (MCI) is a significant and increasingly recognized problem in individuals with type 2 diabetes mellitus (T2DM). +1 more finding

  12. 2025-09-26
  13. 2025-09-25
  14. 2025-09-25

    Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study

    ✓ Peer-reviewed Risk factors Frontiers in Aging Neuroscience

    Key finding: Cerebrovascular disease (OR: 2.39, 95% CI: 1.44-3.97) and peripheral arterial disease (OR: 1.74, 95% CI: 1.03-2.95) were significant risk factors, while higher education (OR 0.85, 95% CI 0.76-0.94) and later diabetes onset (OR: 0.93, 95% CI: 0.88-0.98) were protective. +4 more findings

  15. 2025-09-25
  16. 2025-09-24

    Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program

    ✓ Peer-reviewed Disparities Communications biology

    Key finding: We report significant negative associations (P < 0.002) of the cross-population (P = 1.3 × 10-5) and European (PEA = 3.0 × 10-8) fasting insulin PSs with total cranial volume, and of a metabolic syndrome European PS with general cognitive function (BEA = -0.13, PEA = 0.0002) and lateral ventricular volume (BEA = 0.09, PEA = 0.002). +1 more finding

  17. 2025-09-24

    RNF168 dephosphorylation ameliorates cognitive decline in Aβ-based mouse models of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica communications

    Key finding: Our previous study demonstrated that growth signals regulate genomic stability through RNF168 phosphorylation. +3 more findings

  18. 2025-09-24

    Hearing All About Donepezil: Its Role in the Field of Auditory Processing

    ✓ Peer-reviewed Risk factors Cureus

    Key finding: Her significant history of hearing loss with auditory hallucination impressively responded to the initiation of donepezil.

  19. 2025-09-24

    Brain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention

    ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease

    Key finding: Clusters with diffuse or frontal-predominant cortical thinning, but with more favourable vascular profiles, characterized by lower blood pressure and reduced obesity, showed significantly less cortical thinning (mean thickness, AD-signature, and resilience-signature regions; all p < 0.05) following the intervention. +3 more findings

  20. 2025-09-24

    Effects of triptolide herb on the progression of Alzheimer's disease preclinical models: a systematic review

    ✓ Peer-reviewed Disease mechanisms Neurodegenerative disease management

    Key finding: Tri demonstrates significant multi-target neuroprotective effects in AD preclinical models. +1 more finding

  21. 2025-09-24

    ‘It should be my choice’: voluntary assisted dying needs and preferences of Australians living with dementia

    ✓ Peer-reviewed End-of-life care Ageing and Society

    Key finding: Voluntary assisted dying (VAD) is an end-of-life care option available to eligible Australians living with a terminal condition, though people living with dementia are typically ineligible to choose VAD as part of their end-of-life care. +4 more findings

  22. 2025-09-24

    The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer’s disease

    ✓ Peer-reviewed Prevention trials Scientific Reports

    Key finding: Dietary interventions, particularly the Mediterranean (MeDi) and MIND diets, have been associated with reduced cognitive decline, but their long-term comparative effects remain underexplored. +4 more findings

  23. 2025-09-24

    Gait characteristics and factors associated with fall risk in patients with dementia with Lewy bodies

    ✓ Peer-reviewed Cognitive tests and assessment Frontiers in Neurology

    Key finding: Gait abnormalities are associated with cognitive decline, and reduced gait speed and gait asymmetry are markers of cognitive decline and increased fall risk in patients with established DLB. +4 more findings

  24. 2025-09-24

    Machine learning and data-driven inverse modeling of metabolomics unveil key processes of active aging

    ✓ Peer-reviewed Digital health tools npj Systems Biology and Applications

    Key finding: Routine blood tests confirmed significant differences in AST and ALT.

  25. 2025-09-24

    Empowering community health workers in dementia care in South Texas

    ✓ Peer-reviewed Disparities Journal of Alzheimer s Disease

    Key finding: Alzheimer's disease and related dementias disproportionately affect minority racial and ethnic communities. +1 more finding

Browse the library by subject, with the full score breakdown →