Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 3,076–3,100 of 27,380 studies, newest first · page 124 of 1096.
September 2025 25
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2025-09-30
Trends in Assisted Living and Memory Care Supply From 2019 to 2023
45/100 ✓ Peer-reviewed Risk factors Journal of the American Medical Directors Association
Key finding: Counties with a decrease or no change in AL supply compared with increase in AL supply had a larger proportion of the population aged 65+ years, lower median household income, and were more rural. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-30
Cardiovascular Risk Trajectories and Risk of Developing Stroke and Dementia
56/100 ✓ Peer-reviewed Vascular contributions Neurology
Key finding: Among 2,335 participants (mean age 52.3 ± 11.2 years; 56.6% women), CVD risk trajectories over 10 years were classified as accelerated increase (29.2%), moderate increase (30.9%), or stable (39.9%). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Role of nurses in supporting advance care planning for people living with dementia
25/100 ✓ Peer-reviewed End-of-life care Nursing Older People
Key finding: Advance care planning (ACP) is of particular relevance to people living with dementia due to the gradual loss of decision-making capacity and ability to communicate that they typically experience. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Designing and delivering palliative and end of life care research with people living with HIV: reflections from a co-produced study
32/100 ✓ Peer-reviewed End-of-life care Research Involvement and Engagement
Key finding: This has meant that fewer people are dying as a direct result of HIV, and the life expectancy for people living with HIV is almost the same as the general population in many countries. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-30
Associations of adherence to a healthy sleep pattern with the dementia risk in the UK biobank
44/100 ✓ Peer-reviewed Long-term cohort studies Alzheimer s Research & Therapy
Key finding: During a median follow-up of 13.8 years, 3,035 incident dementia cases were recorded, including 1,304 Alzheimer's disease (AD) cases and 597 vascular dementia (VD) cases. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
High Physical Fitness Is Associated With Better Cognitive Function in Older Adults With Dementia: A Cross-Sectional Study
36/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Aging and Physical Activity
Key finding: A higher GPF was associated with better cognitive function in institutionalized older adults with dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Plasma p‐tau217, NfL, GFAP diagnostic performance and biomarker profiles in Alzheimer's disease, frontotemporal dementia, and psychiatric disorders, in a prospective unselected neuropsychiatry memory clinic
51/100 ✓ Peer-reviewed Lewy body dementia Alzheimer s & Dementia
Key finding: Plasma p-tau217 showed strong diagnostic performance for distinguishing AD from bvFTD (96% accuracy) and PPD (93% accuracy). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Role of Artificial Intelligence in the Diagnosis of Dementia in the Elderly
29/100 ✓ Peer-reviewed Getting a diagnosis International Journal of Community Pharmacy
Key finding: Dementia, a progressive neurodegenerative disorder affecting memory, cognition, and behaviour, poses a major global health challenge in aging populations. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Structure-guided Docking of Benzene-1,3-Disulfonic Acid to the ApoE-HSPG Binding Site at Arginine 136 as a Christchurch-mimetic Therapeutic Strategy for Alzheimer Disease
27/100 ✓ Peer-reviewed Genetics Clinical Neuropharmacology
Key finding: Benzene-1,3-disulfonic acid exhibited strong binding to the Arg136-containing pocket with a top docking score of -5.93 kcal/mol and an estimated inhibition constant (Ki) of 44.6 µmol. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-30
Social Disparities, Delirium Occurrence, and Related Outcomes Among Hospitalized Older Adults
44/100 ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society
Key finding: A total of 260,200 older adults were screened for delirium (median [IQR] age in years: 78.0 [74.0-84.0]; female: 143,402 [55.1%]; non-Hispanic Black: 40,737 [15.8%]; Hispanic: 30,760 [11.9%]; median [IQR] Area Deprivation Index: 4.0 [2.0-6.0]; median [IQR] Charlson Comorbidity Index: 10.0 [8.0-13.0]). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Anti-Amyloid Therapies for Alzheimer’s Disease: Progress, Pitfalls, and the Path Ahead
45/100 ✓ Peer-reviewed Treatments International Journal of Molecular Sciences
Key finding: On the other hand, they also create significant safety risks, including amyloid-related imaging abnormalities (ARIA) and substantial operational requirements for health systems that are already under pressure.
Full summary, score breakdown and related studies → Original source
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2025-09-29
Impaired Synaptic Plasticity Mechanisms in Alzheimer's Disease
43/100 ✓ Peer-reviewed Disease mechanisms Metabolic brain disease
Key finding: In particular, disruption of long-term potentiation (LTP) within the hippocampus, a region essential for learning and memory, plays a central role. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Obstructive Sleep Apnea and Aging: A Narrative Review
43/100 ✓ Peer-reviewed Risk factors Sleep medicine research
Key finding: It can greatly increase patient sleepiness, and is associated with cardiovascular and neurological disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-29
Glucagon-like peptide-1 receptor agonists and mental health: a narrative review of emerging benefits and risks
63/100 ✓ Peer-reviewed Drug development Journal of Yeungnam medical science
Key finding: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), originally developed for type 2 diabetes mellitus and obesity, are increasingly recognized for their significant impact on the central nervous system, leading to reports of both beneficial and adverse mental health effects. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Reversible tau hyperphosphorylation in hibernation: a blood biomarker and brain tissue study
46/100 ✓ Peer-reviewed Biomarkers Acta neuropathologica
Key finding: We also analyzed brain tissue from ten golden Syrian hamsters (Mesocricetus auratus) subjected to induced torpor (hibernation) versus euthermic (non-hibernating) states by quantifying multiple phosphorylated and non-phosphorylated tau peptides with an IP-MS method previously applied in human brain tissue. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Socioeconomic status modifies the association between adherence to the Mediterranean diet and cognitive outcomes: results from the Collaborative PROMED-COG Pooled Cohorts Study
46/100 ✓ Peer-reviewed Prevention trials Social Psychiatry and Psychiatric Epidemiology
Key finding: Cognitive decline occurred in 38.1% of participants but was not associated with MD adherence. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
General practitioners’ practices and training needs in dementia care: a comparison of urban and rural areas in Kazakhstan
41/100 ✓ Peer-reviewed Disparities Aging & Mental Health
Key finding: Targeted interventions, as enhanced training and improved support systems, are essential to address these disparities and better support GPs. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-09-29
Effects of a virtual iSupport Program on carers and people with dementia
62/100 ✓ Peer-reviewed Caregiving Alzheimer s & Dementia
Key finding: One hundred forty-nine carers enrolled in the study. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Dependency Grammar Approach to the Syntactic Complexity in the Discourse of Alzheimer Patients
36/100 ✓ Peer-reviewed Brain scans and imaging Behavioral Sciences
Key finding: A total of 150 adults with AD and 150 healthy controls (HC) responded in English to interview prompts based on the Cookie Theft picture description task, and the results were compared. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-29
Dementia prevalence in the Wisconsin Longitudinal Study
55/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: Cognitive status was determined for 5414 participants, with a dementia prevalence of 8.9% when assessed at a mean age of 81 years. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-28
Age-Associated Transcriptomic and Epigenetic Alterations in Mouse Hippocampus
43/100 ✓ Peer-reviewed Genetics Aging cell
Key finding: Aging represents a major risk for human neurodegenerative disorders, such as dementia and Alzheimer's disease, and is associated with a functional decline in neurons and impaired synaptic plasticity, leading to a gradual decline in memory. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-28
Multicomponent interventions and technologies to reduce the burden of frailty, functional, and cognitive decline: insights from the Age-It Research Program
41/100 ✓ Peer-reviewed Prevention trials The Journals of Gerontology Series B
Key finding: The project is expected to generate evidence on the effectiveness, feasibility, and cost-effectiveness of multidomain interventions implemented across diverse real-world settings, including community, hospital, and long-term care. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-28
Small-Molecule Inhibitors of Amyloid Beta: Insights from Molecular Dynamics—Part B: Natural Compounds
33/100 ✓ Peer-reviewed Disease mechanisms Pharmaceuticals
Key finding: It suggests that Aβ aggregation is the initial trigger of neurotoxicity, setting off a cascade of pathological events including inflammation, oxidative stress, tau hyperphosphorylation, synaptic dysfunction, and, ultimately, dementia.
Full summary, score breakdown and related studies → Original source
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2025-09-28
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial
58/100 ✓ Peer-reviewed Cognitive tests and assessment Drugs
Key finding: A total of 325 participants enrolled and received study drug. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-09-27
XPro1595, a Selective Soluble TNF Neutralizer, in Early Alzheimer’s Disease with Inflammation (ADi): Results from the Phase 2 MINDFuL Trial
16/100 ⚠ Preprint — not yet peer-reviewed Treatments medRxiv
Key finding: The complete absence of ARIA distinguishes XPro1595 from amyloid-targeting therapies and supports its potential for use in combination strategies and potentially for those at a higher risk of ARIA. +4 more findings
Scored 26 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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