alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,601–15,625 of 27,380 studies, newest first · page 625 of 1096.

December 2016 8

  1. 2016-12-02

    Palliative care interventions in advanced dementia

    ✓ Peer-reviewed End-of-life care The Cochrane database of systematic reviews

    Key finding: Data collection and analysis Two review authors independently assessed for inclusion all the potential studies we identified as a result of the search strategy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-12-01

    Palliative care for dementia patients

    ✓ Peer-reviewed End-of-life care Geriatrie et psychologie neuropsychiatrie du vieillissement

    Key finding: Dementia is a life-limiting disease without curative treatments but the data suggest that advanced dementia is not viewed as a terminal diagnosis by physicians. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2016-12-01

    Gamma frequency entrainment attenuates amyloid load and modifies microglia

    ✓ Peer-reviewed Inflammation and the immune system Nature

    Key finding: Gene expression profiling revealed induction of genes associated with morphological transformation of microglia, and histological analysis confirmed increased microglia co-localization with Aβ. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2016-12-01

    Computerized Structured Cognitive Training in Patients Affected by Early-Stage Alzheimer's Disease is Feasible and Effective: A Randomized Controlled Study

    ✓ Peer-reviewed Cognitive tests and assessment Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    Key finding: Patients in the experimental group showed a significant improvement in various neuropsychological domains, and their achievements were stable after 6 months. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-12-01

    Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury

    ✓ Peer-reviewed Risk genes beyond APOE Science translational medicine

    Key finding: However, no marker related to microglia has been included in the temporal evolution models of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-12-01

    Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults

    ✓ Peer-reviewed Caregiving JAMA psychiatry

    Key finding: Loneliness is a perceived state of social and emotional isolation that has been associated with cognitive and functional decline and an increased risk of incident AD dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-12-01

    Considering sex and gender in Alzheimer disease and other dementias

    ✓ Peer-reviewed Prevention and risk Dialogues in clinical neuroscience

    Key finding: The degree to which the resulting health conditions (eg, obesity, type 2 diabetes, and cardiovascular disease) impact dementia risk varies by sex. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-12-01

    Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment: The Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Study

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Diagnostic change occurred in 46 patients (79%) having both a previous diagnosis of AD and an amyloid-negative scan (P Conclusions and relevance Amyloid PET in addition to routine assessment in patients with cognitive impairment has a significant effect on diagnosis, diagnostic confidence, and drug treatment. +3 more findings

    Full summary, score breakdown and related studies → Original source

November 2016 17

  1. 2016-11-30

    Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline

    ✓ Peer-reviewed Risk factors American journal of neurodegenerative disease

    Key finding: White Matter Disease is increasingly being recognized as an important cause of cognitive decline and dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-11-30

    Falls, Cognitive Impairment, and Gait Performance: Results From the GOOD Initiative

    ✓ Peer-reviewed Clinical safety Journal of the American Medical Directors Association

    Key finding: These findings suggest that non-AD, but not AD dementia, is associated with increased falls in comparison with CHIs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-11-29

    Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

    ✓ Peer-reviewed Prevention trials Free radical biology & medicine

    Key finding: Very similar to the effects of the stress of exercise on muscle cells, emerging findings suggest that neurons respond to activity by activating signaling pathways (e.g., Ca 2+ , CREB, PGC-1α, NF-κB) that stimulate mitochondrial biogenesis and cellular stress resistance. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-11-29

    Inpatient Palliative Care for Neurological Disorders: Lessons from a Large Retrospective Series

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: Hospital-based palliative care is primarily utilized to clarify goals of care in neurological patients and that advance directives were commonly not completed prior to consultation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2016-11-29

    Cognitive Training in the Elderly: Bottlenecks and New Avenues

    ✓ Peer-reviewed Prevention trials Journal of cognitive neuroscience

    Key finding: As in most budding fields, there are still considerable inconsistencies across methodologies and results, as well as a lack of consensus on a comprehensive assessment protocol.

    Full summary, score breakdown and related studies → Original source

  6. 2016-11-28

    Hearing impairment and risk of Alzheimer's disease: a meta-analysis of prospective cohort studies

    ✓ Peer-reviewed Risk factors Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    Key finding: The overall combined relative risk of people with hearing impairment to develop Alzheimer's disease was 4.87 (95% CI 0.90-26.35; p = 0.066), compared with the control group. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-11-28

    Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Neuroscience and biobehavioral reviews

    Key finding: Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an endogenous tracer to measure cerebral blood flow (CBF). +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-11-28

    Oral health status and need for oral care of care-dependent indwelling elderly: from admission to death

    ✓ Peer-reviewed Disparities Clinical oral investigations

    Key finding: When compared to edentulous elderly patients, patients with remaining teeth were younger at admittance, were more often non-cooperative, and had a poorer oral health and higher need for dental care. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-11-25

    Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: Genetic analyses showed that the triggering receptor expressed in myeloid cells 2 (TREM2) p.R47H variant increases the risk for Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-11-25

    Technology-enhanced multi-domain at home continuum of care program with respect to usual care for people with cognitive impairment: the Ability-TelerehABILITation study protocol for a randomized controlled trial

    ✓ Peer-reviewed Treatments BMC psychiatry

    Key finding: The expected outcome is to ensure the continuity of care from clinical practice to the patient's home, enabling also cost effectiveness and the empowerment of patient and caregiver in the care process, positively impacting on their quality of life.

    Full summary, score breakdown and related studies → Original source

  11. 2016-11-24

    Clinical Amyloid Imaging

    ✓ Peer-reviewed Biomarkers Seminars in nuclear medicine

    Key finding: Although the overall impact of amyloid imaging is still being evaluated, the Society of Nuclear Medicine and Molecular Imaging and Alzheimer's Association Amyloid Imaging Task Force have created appropriate use criteria for the standard clinical use of amyloid PET imaging. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2016-11-23

    Caregiver burden and prevalence of depression, anxiety and sleep disturbances in Alzheimer's disease caregivers in China

    ✓ Peer-reviewed Caregiving Journal of clinical nursing

    Key finding: Depression, anxiety and sleep problems are the main challenges that are faced by family caregivers of patients with Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-11-22

    Targeting Functional Decline in Alzheimer Disease: A Randomized Trial

    ✓ Peer-reviewed Treatments Annals of internal medicine

    Key finding: The authors could not definitively demonstrate whether the addition of 2 years of in-home occupational therapy to a collaborative care management model slowed the rate of functional decline among persons with Alzheimer disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-11-19

    Human gut microbiota: the links with dementia development

    ✓ Peer-reviewed Disease mechanisms Protein & cell

    Key finding: New researches indicate that gastrointestinal tract microbiota are directly linked to dementia pathogenesis through triggering metabolic diseases and low-grade inflammation progress.

    Full summary, score breakdown and related studies → Original source

  15. 2016-11-18

    Predictors of care home and hospital admissions and their costs for older people with Alzheimer's disease: findings from a large London case register

    ✓ Peer-reviewed Digital health tools BMJ open

    Key finding: Most people with dementia prefer to remain in their own homes, and funding bodies see this as cheaper than institutionalisation.

    Full summary, score breakdown and related studies → Original source

  16. 2016-11-18

    Microglia and brain macrophages: An update

    ✓ Peer-reviewed TREM2 and immune genetics Neuropathology : official journal of the Japanese Society of Neuropathology

    Key finding: Previous studies have indicated that almost no neurological diseases exist without microglial activation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-11-18

    Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: In multivariate analyses, baseline age, University of Pennsylvania Smell Inventory Test (UPSIT) scores, CSF amyloid - (Aβ 42 ) to t-tau ratio, and APOE status were associated with change in MoCA scores over time. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →