Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
-
28/100
Delirium superimposed on dementia (DSD) is a frequent but underrecognised condition that complicates care in older adults.
Why it matters
This review outlines that delirium superimposed on dementia is frequent but underrecognised, and that failure to distinguish between the two can delay treatment and worsen outcomes. It emphasizes early identification, nonpharmacological interventions, and cautious medication use, and discusses delirium as a potential contributor to neurodegeneration.
-
Recent studies indicate that having a billed AWV is associated with increases in preventive care services such as vaccinations, cancer screening, and dementia diagnosis.
Why it matters
This session summary notes that receiving a Medicare Annual Wellness Visit is associated with increases in services such as dementia diagnosis, and describes efforts to improve dementia care pathways. It does not test a treatment, cure, or prevention for Alzheimer's disease.
-
Patients and their caregivers and families confronting dementia often face heavy burdens from difficult-to-control symptoms, uncertainty about the future, and a high risk of care partner burnout.
Why it matters
This review of neuropalliative care in dementia notes that major breakthroughs have been elusive in treating many common symptoms of dementia, though research has clarified risks and benefits of commonly used medications. It discusses weighing mortality benefits of cholinesterase inhibitors against simplification when deprescribing.
-
1 in 3 older adults die with or from dementia.
Why it matters
This lecture reviews the history and current trends of hospice use for older adults with dementia, who now make up 50% of the 1.7 million hospice enrollees annually, even though hospice was designed for cancer patients. It discusses concerns about misuse of the Medicare Hospice Benefit and the role of hospice and alternative care models in end-of-life care.
-
Dementia-specific ACP/AD require a relational, flexible and ethically grounded approach that evolves with the individual’s condition.
Why it matters
This scoping review of literature from 2014 to 2024 identified stakeholders including healthcare professionals, family caregivers, people with dementia, the public, policymakers, and researchers. It found promising interventions such as structured communication models and psychoeducational programs, though few have been fully adapted for dementia.
-
The analysis reveals a significant acceleration in research activity after 2017.
Why it matters
This bibliometric analysis maps research on palliative care in psychiatric disorders, identifying a cluster on palliative care in dementia and related cognitive disorders. It highlights an urgent need for integrated care pathways and expanded global research.
-
There is very little documented evidence on the experiences of healthcare professionals caring for their own family outside of their role.
Why it matters
This article shares one family member's personal reflections on communication and end-of-life care for her mother with dementia. It does not test any treatment, cure or prevention.
-
In the context of an aging population, China’s elderly care market is experiencing a period of significant transformation.
Why it matters
This study compares home-based and institutional elderly care models in urban China for disabled and dementia patients, finding that home-based care is mainstream but faces nursing shortages and weak community support. Institutional care offers professional nursing but is constrained by high costs and mismatches between bed supply and demand.
-
This review analyzes current data on the epidemiology, pathogenesis, clinical features, and approaches to the treatment of cognitive impairments in diabetes mellitus (DM).
Why it matters
This review states that diabetes mellitus is an independent risk factor for dementia, particularly Alzheimer's disease and vascular dementia, and describes mechanisms including brain insulin resistance, hyperglycemia, beta-amyloid accumulation, tau pathology, oxidative stress, vascular dysfunction, and neuroinflammation. It notes that long-term metformin use is associated with a reduced risk of dementia, depending on therapy duration.
-
The Ct group and Ct+ee group performed significantly better than the control group in behavioural tasks and had improved dendrite profiles of DG and basal tree of CA1 region of hippocampus.
Why it matters
In this study with aging rats, cognitive training and enriched environment improved behavioral task performance and neuronal health in the hippocampus. These are animal findings and cannot be directly applied to treating or preventing Alzheimer's disease in people.
-
Parameters such as clinical status, GCA scale, MTA scale, Fazekas scale, strategic infarction, Koedam score, stroke, hypertension, diabetes mellitus, dyslipidemia, and cardiovascular disease do not have significant correlations with MoCA-INA scores.
Why it matters
In this small study of 28 dementia patients, no statistical differences were found between multiple MRI parameters and MOCA-INA scores. It does not provide evidence for treating, curing, or preventing Alzheimer's disease.
-
This paper examined the prevalence of and risk factors associated with unmet needs for activities of daily living (ADL) for older adults dying with dementia.
Why it matters
This study looked at unmet daily living care needs among older adults dying with dementia and found that older age, hospice use, residential care and greater ADL disability were linked to fewer unmet needs. It concerns end-of-life care quality, not treating, curing or preventing Alzheimer's disease.
-
28/100
While this process allows machine learning models to make more precise and reliable diagnoses, systems developed on the basis of Dr. Roman Poznanski's DOT (Dynamic Optimization of Thought) theory offer a new method in the diagnosis of neurological diseases.
Why it matters
Artificial intelligence has been used to help diagnose neurological diseases and to slow their progression by optimizing individualized treatment plans. Systems based on DOT theory are proposed as a future method for more integrated diagnosis, monitoring, and treatment, but these are described as future possibilities rather than established treatments.
-
Dietary patterns play a crucial role in shaping mental health, as they influence the availability of essential nutrients that support brain function and emotional regulation.
Why it matters
The paper states that diets high in antioxidants and healthy fats support brain health and may reduce the risk of cognitive decline and Alzheimer's disease, while processed foods, sugars, and unhealthy fats are linked to mental health problems. It calls for prospective and intervention studies, so the evidence is not yet enough to confirm that diet prevents Alzheimer's disease.
-
There are many types of Dementia‐Friendly Communities (DFCs), and communities define and implement them in different ways.
Why it matters
This describes how local governments in the East of England are setting up a Dementia-Friendly Communities programme after the national accreditation scheme ended. It is about community awareness, support and services, not about treating, curing or preventing Alzheimer's disease.
-
Polypharmacy is an important healthcare issue, especially in elderly patients with dementia.
Why it matters
This study found that a financial incentive scheme for medication review was not associated with a reduction in the number of medication classes at discharge among older inpatients with dementia. No significant changes were observed immediately after the scheme's introduction or over time.
-
Neighborhood disadvantage was selectively associated with cognitive measures heavily influenced by executive function, namely using an efficient word generation strategy, and incorporating feedback to guide problem-solving.
Why it matters
In 46 older adults with metabolic syndrome, greater neighborhood disadvantage was linked to lower performance on word generation and problem-solving, with education quality playing a mediating role for word generation. The small sample size limits how much these findings can be generalized, and no treatment was tested.
-
Twenty-three patients participated. Mean age was 82 years.
Why it matters
This small pilot with 23 patients described implementing chronic care management services and the revenue they generated. It is about care coordination and billing, not about treating, curing, or preventing Alzheimer's disease.
-
Benefits Beyond Auditory Rehabilitation Research conducted by Frank Lin and colleagues found that individuals with untreated mild, moderate, and severe hearing loss had, respectively, a twofold, threefold, and fivefold increased risk of dementia compared with individuals with normal hearing. 4 Research suggests that early auditory rehabilitation is important for people of all ages, including older adults, as it can provide benefits and improvements beyond hearing ability such as cognitive function and mitigation of depression.
Why it matters
The article reports that untreated hearing loss is linked to a higher risk of dementia, and that cochlear implants should be discussed as possibly helping cognitive function in older adults with severe-to-profound hearing loss. It does not show that cochlear implants prevent or cure Alzheimer's disease.
-
The use of hierarchical Bayesian small area models, which take survey estimates along with auxiliary data as input to produce official statistics, has increased in recent years.
Why it matters
This study is about statistical methods for county-level crop yield estimates, not Alzheimer's disease, so it does not provide information on treating, curing or preventing Alzheimer's. It proposes ways to handle unreliable sampling variances in small area models.
-
Better understanding of sociodemographic factors of our patient group is key to improving equity of care.
Why it matters
This review of published literature found abundant research on age, race, geographical variation, sex, and gender in dementia care. Evidence was lacking for relationships between dementia care and disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, religion and belief, sexual orientation, and immigration and settlement.
-
This article addresses the potential legal ramifications for neurologists caring for patients with Alzheimer disease (AD) who elect neither to prescribe aducanumab nor to refer patients with AD for treatment with aducanumab.
Why it matters
This article addresses the potential legal ramifications for neurologists who elect neither to prescribe aducanumab nor to refer patients with Alzheimer disease for treatment with it. It notes that to prevail, a plaintiff would have to establish that the failure to prescribe or refer was a breach of the standard of care, and that controversy surrounds the FDA's approval process for aducanumab.
-
The mitigation measures (e.g., lockdown policies) in response to the COVID-19 pandemic impacted food systems in unprecedented ways, in both scope and immediacy.
Why it matters
This case study examines how COVID-19 public health regulations changed grocery store food purchases, not Alzheimer's disease, so it offers nothing on treating, curing or preventing Alzheimer's. It found consumers increased purchases in most food groups during the pandemic.
-
I’ll be applying soon. Claire: Maddie, what do you think will be different for you when you come to visits with us versus visits with an adult provider?
Why it matters
This roundtable discussion is about transitions in pulmonary hypertension care from pediatric to adult providers. It does not report any treatment, cure, or prevention for Alzheimer's disease.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults
- Supporting informal caregivers of dementia patients in China: action needed
- Factors influencing medication adherence among U.S. Medicare beneficiaries with Alzheimer’s disease and related dementia (ADRD)
- Longitudinal, Bidirectional Association between Gait Speed and Cognitive Function in Community-Dwelling Older Adults without Dementia
- Mild cognitive impairment, Alzheimer's disease dementia, and predictors of driving cessation: A 7-year longitudinal prospective study
- Palliative care needs of seriously ill, older adults presenting to the emergency department
- Associations between stroke and vascular dementia combing Mendelian randomization with network pharmacology
- A randomized trial of comprehensive geriatric assessment in the care of hospitalized patients
- Brain Age Gap Predicts Progression to Dementia in SCD and MCI
- Estimating the impact of risk factor reduction on dementia prevalence in New Zealand