Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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KEY POINTSO_LIThis paper demonstrates the feasibility of implementing Geriatric ED programs with targeted support for people living with or at risk for dementia across three distinct health systems in San Francisco.
Why it matters
This paper describes implementing Geriatric Emergency Department programs with targeted support for people living with or at risk for dementia across three health systems. It addresses emergency care delivery and feasibility, not the treatment, cure or prevention of Alzheimer's disease itself.
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Respondents who reported no difficulty deciding (DECIDE = 2) had substantially lower odds of SCD than those who reported difficulty (DECIDE = 1; aOR approximately 0.13; FDR < 0.05).
Why it matters
This analysis found that respondents who reported no difficulty deciding had much lower odds of subjective cognitive decline than those who reported difficulty. It concerns a survey-based prediction benchmark and does not test any treatment, cure or prevention.
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BackgroundAsymptomatic carotid artery stenosis (ACAS) increases the risk of stroke, and is associated with cognitive decline.
Why it matters
Risk of dementia was higher with carotid plaque without stenosis and with full occlusion, but no significant effect was found with mild, moderate or severe stenosis. The authors say their findings do not support revascularisation for cognitive benefit in most cases with asymptomatic carotid artery stenosis.
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The term Precision Aging describes an approach that focuses on multi-domain profiles of risks impacting individual trajectories of age-related cognitive functioning.
Why it matters
Among adults without a dementia diagnosis, those with prominent risk in specific domains performed worse on memory tests than a low-risk group. This is a clustering study of risk profiles and does not test any treatment or prevention.
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The Dementia Trials Accelerator (DTA) is a UK-wide programme designed to improve the feasibility, efficiency, and inclusiveness of recruitment into clinical trials of dementia and related brain-health conditions.
Why it matters
This UK programme aims to make dementia trial recruitment faster and more inclusive by linking existing cohorts and pre-screening participants aged 65 to 75, with a target of at least 10,000 people. It is an infrastructure and recruitment initiative, not a treatment or prevention study.
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Cognitively normal older adults are often regarded as a homogeneous population in preventive and disease-modifying clinical trials for dementia.
Why it matters
Among cognitively normal older adults, a high-burden subgroup identified by clustering had worse memory and executive function and much higher rates of conversion to mild cognitive impairment or dementia within two years. The authors present this as a data-driven way to stratify people for prevention trials.
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BackgroundAlzheimers Disease and Related Dementias (ADRD) is a growing global public health challenge, and caregivers experience high rates of burden, unmet needs, and system failures.
Why it matters
This analysis of caregiver forum posts found that burden and unmet needs were very common and often co-occurred with system failures, with patterns differing by caregiver role and relationship. It describes caregiving challenges and does not test any treatment, cure or prevention for Alzheimer's disease.
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Despite elevated risk profiles for dementia, Black women are often absent in cultural narratives about dementia.
Why it matters
This paper argues that Black women are often absent from cultural narratives about dementia and that person-centered approaches may highlight conditions contributing to their elevated risk, such as economic precarity, racism, and caregiving responsibilities. It is a conceptual paper and does not test a treatment, cure, or prevention.
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The “WarioWare: Move It!” intervention significantly improved physical flexibility, joint range of motion, motor coordination, hand dexterity, and cognitive function among older adults with mild cognitive impairment or dementia residing in rural LTCFs.
Why it matters
This randomized controlled trial found that an exergame-based training program significantly improved physical flexibility, joint range of motion, motor coordination, hand dexterity, and cognitive function in older adults with mild cognitive impairment and dementia in rural long-term care facilities. The study has been retracted, so its results should not be relied upon.
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16/100
We examine the scaling of Small Area Fair Market Rents (SAFMRs) of Housing Choice Voucher (HCV) program in 2018.
Why it matters
This study examined how a housing voucher policy that sets subsidies at the ZIP code level affected where recipients moved. It provides no information on treating, curing or preventing Alzheimer's disease.
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Neighborhood disadvantage is associated with worse health and cognitive outcomes.
Why it matters
Among cognitively unimpaired people, neighborhood disadvantage was linked to differences in local cortical organization, which partly explained the link between disadvantage and cognitive performance. This suggests a possible brain-based mechanism, but it is a cross-sectional study and does not test treatment or prevention.
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16/100
Cultural narratives shape how we think about the world, including how we decide when the end of life begins.
Why it matters
This essay argues that the six-month hospice rule is not a meaningful marker for people with advanced dementia, being both too early for conversations and too late for decision-making capacity. It is about end-of-life care policy and communication, not about treating, curing, or preventing Alzheimer's disease.
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We study the design of optimal (private and/or social) insurance schemes for formal home care and institutional care.
Why it matters
This theoretical study designs optimal insurance schemes for home versus nursing home long-term care. It provides no information on treating, curing or preventing Alzheimer's disease.
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It is estimated that for people aged 65 years and older, the risk of developing Alzheimer’s disease was nearly double for women compared with men (Weinstein et al., 2012).
Why it matters
This article describes public health efforts and policy recommendations for reducing dementia risk, noting that Alzheimer's risk was nearly double for women compared with men aged 65 and older. It does not report results of a treatment, cure, or prevention trial.
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Dementia and hearing loss are both highly prevalent conditions among older adults.
Why it matters
Using UK Biobank data, this cohort study examined whether hearing aid use was associated with lower risk of all-cause and cause-specific dementia in middle-aged and older adults. It reports an association and does not prove that hearing aids prevent dementia.
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Marginal utility of financial resources when needing long-term care, and the related incentives for precautionary savings and insurance, may vary significantly by whether one receives care at home or in a nursing home.
Why it matters
This economic analysis found that the marginal utility of financial resources is significantly higher when care is received at home rather than in a nursing home. This implies stronger incentives to save for those expecting home care and a higher value for additional home care subsidies than for nursing home subsidies.
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Research on food waste has attracted particular interest in recent years.
Why it matters
This literature review covers analytics and modeling methods for preventing food waste in grocery store operations. It has no relevance to treating, curing, or preventing Alzheimer's disease.
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We analyze the impact of a temporary shock to food supply on households’ dietary choices.
Why it matters
This study found that hurricane-induced grocery store closures were linked to a decrease in the nutritional value of household purchase baskets for nine months after stores reopened. It has no relevance to treating, curing, or preventing Alzheimer's disease.
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Future studies are encouraged to adopt personalized internet-based supportive interventions to improve the health of family caregivers and their care recipients.
Why it matters
This systematic review and meta-analysis found that internet-based supportive interventions significantly ameliorated depressive symptoms in family caregivers of people with dementia. The study is noted as retracted.
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In fact, average benefits are considered modest compared with the benefits of other developed countries.
Why it matters
This article discusses political trends affecting aging policy in America, including Medicare Advantage rules allowing nonmedical services for chronically ill enrollees. It does not address treating, curing, or preventing Alzheimer's disease.
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Phase 1 (realist review; 86 papers) identified that a key intervention component was the activities enabling the development of moments of connection.
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This includes adapting and disseminating care delivery innovations from one system to another, as well as measuring and sharing in the improved outcomes and reduced costs that might result.
Why it matters
This review discusses adapting long-term care innovations, such as home-based primary care, between health systems and notes that no single model consistently reduced long-term institutionalization. It does not address treating, curing, or preventing Alzheimer's disease.
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The largest increase in the older adult population in U.S. history is something to celebrate—yet, at the same time, current and future trends signal that financial exploitation is, and will continue to be, a significant threat for older adults.
Why it matters
This paper describes triggers that bank staff might notice to help prevent financial exploitation of older adults, including signs such as disorientation or trouble with paperwork. It is about protecting older adults' finances and does not test any treatment, cure, or prevention for Alzheimer's disease.
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Why it matters
The manual of diagnostic criteria for mental disorders, dementia among them. Standardising how conditions are defined and diagnosed supports consistent care and research, but does not treat or prevent Alzheimer's disease.
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The results presented are sufficiently encouraging to recommend that the DEMQOL instruments be used alongside a generic measure such as the European Quality of Life-5 Dimensions (EQ-5D) in future studies of interventions in dementia as there was evidence that they can be more sensitive for patients at the milder end of disease and some limited evidence that the person with dementia measure may be able to reflect deterioration.
Why it matters
This study developed preference-based measures from the DEMQOL instruments for use in economic evaluation of dementia interventions. It does not test any treatment, cure, or prevention for Alzheimer's disease.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Availability and use of telehealth services among patients with ADRD enrolled in traditional Medicare vs. Medicare advantage during the COVID-19 pandemic
- Utilization of Occupational and Physical Therapy Home Health Visits Among People Living With Dementia With Varying Social Determinants of Health
- Identifying syntactic biomarkers of cognitive impairment in Mandarin-speaking older adults by applying machine learning approaches across multiple speech tasks
- PET studies in dementia
- Criminal Behavior in Frontotemporal Dementia: A Multimodal MRI Study
- Multisensory Stimulation as an Intervention Strategy for Elderly Patients With Severe Dementia: A Pilot Randomized Controlled Trial
- Population‐Based Norms for the Montreal Cognitive Assessment in Arab Adults
- The Montreal Cognitive Assessment (MoCA) is superior to the Mini-Mental State Examination (MMSE) for the detection of vascular cognitive impairment after acute stroke
- Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study
- Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review