Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. An online multidomain lifestyle intervention to prevent cognitive decline in at-risk older adults: a randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 93 out of 100. Nature medicine 2025-01-28 Prevention trials

    Effective, scalable dementia prevention interventions are needed to address modifiable risk factors given global burden of dementia and challenges in developing disease-modifying treatments.

  2. Sixty-Day Outcomes Among Patients Hospitalized With COVID-19

    ✓ Peer-reviewed alzhub usefulness score 86 out of 100. Annals of Internal Medicine 2020-11-11 Risk factors

    Of 1648 patients with COVID-19 admitted to 38 hospitals, 398 (24.2%) died during hospitalization and 1250 (75.8%) survived.

  3. Predicting discharge to institutional long-term care following acute hospitalisation: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 86 out of 100. Age and ageing 2017-07-01 Health systems and care delivery

    from 9,176 records, we included 23 studies (n = 354,985 participants).

  4. Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 85 out of 100. JAMA network open 2019-03-01 Digital health tools

    Implementation facilitation that engages clinicians under typical practice conditions can enhance evidence-based team processes; its effect on self-reported overall population health status was negligible, although health status improved for individuals with complex conditions and hospitalization rate declined.

  5. Multidomain Dementia Risk Reduction in Primary Care is Feasible: A Proof-of-concept study

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. Journal of Alzheimer's disease : JAD 2024 Cognitive tests and assessment

    The interventions were positively perceived, with 72.0% finding the consultation informative and 69.2% considering the app useful.

  6. The Impact of Pandemic-Related Restrictions on Dementia Risk Factors in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. Journal of applied gerontology : the official journal of the Southern Gerontological Society 2023-11-06 Prevention trials

    Adults aged 65+ are at highest risk for severe COVID-19 outcomes, and prior to the distribution of vaccines in the U.S., were strongly advised to quarantine at home to reduce risk of infection.

  7. Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. JAMA network open 2019-05-03 Cognitive tests and assessment

    These results provide further support for behavioral interventions for persons with MCI.

  8. Impact of the COVID-19 Pandemic on Older Adults: Rapid Review

    ✓ Peer-reviewed alzhub usefulness score 83 out of 100. JMIR aging 2021-04-12 Prevention trials

    Our results highlight the need for adequate isolation and protective measures.

  9. Adoption of Telemedicine for Dementia Care in Nigeria: Scoping Review

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Interactive journal of medical research 2025-10-27 Caregiving

    Among the 23 studies, 10 (43.5%) focused on mobile health apps, 8 (34.8%) on video consultations, and 5 (21.7%) on remote monitoring tools.

  10. A mindfulness-based multicomponent caregiver intervention (PAACC): objectives, study design, and cohort description

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Alzheimer's & dementia (New York, N. Y.) 2025-03-24 Caregiving

    Baseline assessments were conducted on 133 family caregivers of veterans living with dementia.

  11. Interventions to Reduce Loneliness in Community-Living Older Adults: a Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Journal of general internal medicine 2024-01-10 Risk factors

    A total of 5971 titles were reviewed and 60 studies were included in the analysis, 36 RCTs and 24 observational studies.

  12. Comprehensive Older Adult and Caregiver Help (COACH): A person-centered caregiver intervention prevents elder mistreatment

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Journal of the American Geriatrics Society 2023-10-04 Caregiving

    The treatment group had no EM after intervention completion (assessed at 3-month follow-up), a significantly lower rate than the control group (treatment = 0%, control = 23.1%, p = 0.010).

  13. Dementia Incidence, Burden and Cost of Care: A Filipino Community-Based Study

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Frontiers in public health 2021-05-14 Costs and economics

    The crude incidence rate was 16 (CI: 13-20) cases per 1,000 person-years (pyr) with 17 (CI: 12-21) per 1,000 pyr for females and 14 (CI: 9-21) per 1,000 pyr for males.

  14. The Impact of COVID-19 Confinement on Cognition and Mental Health and Technology Use Among Socially Vulnerable Older People: Retrospective Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Journal of medical Internet research 2022-02-22 Cognitive tests and assessment

    Our findings show that the first months of the outbreak did not significantly impact the cognition, quality of life, perceived health status, and depression of our study population when making comparisons with baseline assessments prior to the outbreak.

  15. Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. BMJ open 2021-06-09 Cognitive tests and assessment

    Profiles of high risk for future dementia are well understood and are likely to concern mostly those in low-income and middle-income countries and people at greater disadvantage in high-income countries.

  16. Diabetes in Older Adults: A Consensus Report

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Journal of the American Geriatrics Society 2012-10-25 Brain scans and imaging

    More than 25% of the U.S. population aged ≥ 65 years has diabetes mellitus (hereafter referred to as diabetes),1 and the aging of the overall population is a significant driver of the diabetes epidemic.

  17. Communication Bridge-2 randomized controlled trial: Recruitment and baseline features

    ✓ Peer-reviewed alzhub usefulness score 80 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-11-26 Clinical trials

    Ninety-five participant dyads (PPA mean baseline age: 67.1; 48% female) from four countries were enrolled and randomized.

  18. Technology caregiver intervention for Alzheimer's disease (I-CARE): Feasibility and preliminary efficacy of Brain CareNotes

    ✓ Peer-reviewed alzhub usefulness score 80 out of 100. Journal of the American Geriatrics Society 2023-09-14 Caregiving

    The enrollment rate was acceptable despite pandemic related challenges (53/60 target recruitment sample).

  19. Costs were calculated using cost function figures compared with usual costs.

  20. Caring for Dementia Caregivers: Psychosocial Factors Related to Engagement in Self-Care Activities

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Behavioral sciences (Basel, Switzerland) 2023-10-18 Caregiving

    Caregivers often prioritize the needs of the care recipient and neglect their own health needs.

  21. A tablet-based intervention for activating nursing home residents with dementia: results from a cluster-randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. International psychogeriatrics 2021-06-29 Cognitive tests and assessment

    Levels of apathy decreased slightly in both groups (mean decrease in AES-I of .61 points, 95% CI -3.54, 2.33 for TBI and .36 points, 95% CI -3.27, 2.55 for CAS).

  22. Effectiveness of person-centered care on people with dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Clinical interventions in aging 2017-02-17 Caregiving

    Nineteen interventional studies, including 3,985 participants, were identified.

  23. Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. BMJ (Clinical research ed.) 2011-07-15 Clinical trials

    A systematic approach to the management of pain significantly reduced agitation in residents of nursing homes with moderate to severe dementia.

  24. Effectiveness of nonpharmacological interventions in delaying the institutionalization of patients with dementia: a meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Journal of the American Geriatrics Society 2008-04-11 Costs and economics

    Contemporary healthcare policies are designed to shape the conditions that can help delay the institutionalization of patients with dementia.

  25. Behavioral vs drug treatment for urge urinary incontinence in older women: a randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. JAMA 1998-12-01 Clinical trials

    Behavioral treatment is a safe and effective conservative intervention that should be made more readily available to patients as a first-line treatment for urge and mixed incontinence.

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