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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,101–24,125 of 27,380 studies, newest first · page 965 of 1096.

May 2004 25

  1. 2004-05-13

    Genetic variation in white matter hyperintensity volume in the Framingham Study

    ✓ Peer-reviewed Long-term cohort studies Stroke

    Key finding: In a previous study of normal elderly male twins, the heritability of quantitative white matter hyperintensity (WMH) volume has been estimated to be high (0.73). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2004-05-12

    Cholinergic enhancement of frontal lobe activity in mild cognitive impairment

    ✓ Peer-reviewed Hippocampus size on brain scans Brain : a journal of neurology

    Key finding: We examined the effects of donepezil hydrochloride (Aricept) on cognition and brain activity in patients with amnestic mild cognitive impairment (MCI), a diagnosis associated with a high risk of developing AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2004-05-11

    Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases

    ✓ Peer-reviewed Risk genes beyond APOE Dalton transactions (Cambridge, England : 2003)

    Key finding: The function of the normal prion protein is unknown, although much of recent research demonstrates the it may be a copper binding protein selective for Cu(II). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2004-05-08

    Experimental cerebral hypoperfusion induces white matter injury and microglial activation in the rat brain

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: Since the lesions are often associated with cerebrovascular risk factors, ischemia emerges as a potential condition for the development of white matter injury. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2004-05-05

    Role for glyoxalase I in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: In situ hybridization analysis revealed expression of glyoxalase I in all brain areas analyzed, both in transgenic and control mice. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2004-05-03

    Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

    ✓ Peer-reviewed Disease mechanisms The Journal of cell biology

    Key finding: Recent studies have suggested that neuronal death in Alzheimer's disease or ischemia could arise from dysfunction of the endoplasmic reticulum (ER). +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2004-05-01

    Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's The European journal of neuroscience

    Key finding: Cognitive impairment is also recognized as a clinical characteristic of schizophrenia, which does not appear to be associated with tau-aggregate formation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2004-05-01

    Neuroleptic drug therapy in older adults newly admitted to nursing homes: incidence, dose, and specialist contact

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: Incident use of neuroleptics in Ontario nursing homes is substantial. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2004-05-01

    Relation of plasma lipids to Alzheimer disease and vascular dementia

    ✓ Peer-reviewed Costs and economics Archives of neurology

    Key finding: We found a weak relation between non-HDL-C, LDL-C, and HDL-C levels and the risk of VaD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2004-05-01

    Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

    ✓ Peer-reviewed Disparities Nature

    Key finding: Although caspase-12 is phylogenetically related to the cytokine maturation caspases, in mice it has been proposed as a mediator of apoptosis induced by endoplasmic reticulum stress including amyloid-beta cytotoxicity, suggesting that it might contribute to the pathogenesis of Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2004-05-01

    Restriction in activity associated with fear of falling among community-based seniors using home care services

    ✓ Peer-reviewed Health systems and care delivery Age and ageing

    Key finding: The results from this study provide information about a group void in the literature pertaining to activity restriction from fear of falling - community-based seniors receiving home care services. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2004-05-01

    Sustained benefit of supportive intervention for depressive symptoms in caregivers of patients with Alzheimer's disease

    ✓ Peer-reviewed Health systems and care delivery The American journal of psychiatry

    Key finding: Counseling and support lead to sustained benefits in reducing depressive symptoms in spouse-caregivers of Alzheimer's disease patients and should be widely available to provide effective, evidence-based intervention for family caregivers.

    Full summary, score breakdown and related studies → Original source

  13. 2004-05-01

    Inflammatory mediators in the elderly

    ✓ Peer-reviewed Prevention and risk Experimental gerontology

    Key finding: Furthermore, there is some evidence that ageing is associated with a dysregulated cytokine response following stimulation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2004-05-01

    Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

    ✓ Peer-reviewed Risk factors Archives of neurology

    Key finding: Diabetes mellitus may be associated with an increased risk of developing AD and may affect cognitive systems differentially. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2004-05-01

    GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila

    ✓ Peer-reviewed Drug development Molecular psychiatry

    Key finding: The results show that overexpression of tau disrupts axonal transport causing vesicle aggregation and this is associated with loss of locomotor function. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2004-05-01

    Lymphocytes as a neural probe: potential for studying psychiatric disorders

    ✓ Peer-reviewed Genetics Progress in neuro-psychopharmacology & biological psychiatry

    Key finding: Taken together, these considerations suggest that lymphocyte could reflect the metabolism of brain cells, and may be exploited as a neural and possible genetic probe in studies of psychiatric disorders.

    Full summary, score breakdown and related studies → Original source

  17. 2004-05-01

    Implications of adult hippocampal neurogenesis in antidepressant action

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of psychiatry & neuroscience : JPN

    Key finding: It has been reported that both physical and psychosocial stress paradigms, as well as some animal models of depression, produce a decrease in hippocampal cell proliferation and neurogenesis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2004-05-01

    Effect of postoperative delirium on outcome after hip fracture

    ✓ Peer-reviewed Clinical safety Clinical orthopaedics and related research

    Key finding: Patients who had postoperative delirium develop had a significantly longer length of hospitalization. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2004-05-01

    Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Significantly, CNS axons in RW mice contained reduced levels of tau when compared with hWT mice, and this was linked to retarded axonal transport and increased accumulation of an insoluble pool of RW but not hWT tau. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2004-05-01

    A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques

    ✓ Peer-reviewed Disease mechanisms Annals of neurology

    Key finding: Interestingly, two presenilin 1 (PS1) mutations (Leu113Pro and insArg352) recently have been associated with familial FTD albeit without neuropathological confirmation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2004-05-01

    HIV-associated nephropathy

    ✓ Peer-reviewed Risk factors AIDS

    Key finding: The high prevalence of injecting drug use among affected patients prompted some authors to conclude that concurrent heroin nephropathy, not HIV-1 infection per se, was responsible for this renal syndrome. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2004-05-01

    The microglial phagocytic role with specific plaque types in the Alzheimer disease brain

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: The role of the microglial cells in the AD brain is controversial, as it remains unclear if the microglia form the amyloid fibrils of plaques or react to them in a macrophage-phagocytic role. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2004-05-01

    Cognitive and behavioural effects of music-based exercises in patients with dementia

    ✓ Peer-reviewed Cognitive tests and assessment Clinical rehabilitation

    Key finding: Public Psychiatric Hospital Rekem, Belgium. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2004-05-01

    Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. A multicentric EEG study

    ✓ Peer-reviewed Cognitive tests and assessment NeuroImage

    Key finding: Resting EEG (10-20 electrode montage) was recorded from 48 mild AD, 20 VaD, and 38 Nold subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2004-05-01

    Amyloid beta(1-42) and phosphorylated tau in CSF as markers for early-onset Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: CSF Abeta42 was significantly lower and CSF total tau and CSF Ptau-181 significantly higher in EAD patients than FTLD patients and control subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →