Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 23,976–24,000 of 27,380 studies, newest first · page 960 of 1096.
September 2004 17
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2004-09-01
A proactive approach to improve end-of-life care in a medical intensive care unit for patients with terminal dementia
43/100 ✓ Peer-reviewed End-of-life care Critical care medicine
Key finding: Proactive interventions from a palliative care consultant within this subset of patients improved end-of-life care and decreased use of superfluous resources. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
Occupational therapy for community dwelling elderly people: a systematic review
64/100 ✓ Peer-reviewed Clinical safety Age and ageing
Key finding: This review shows that occupational therapy interventions for community dwelling elderly people results in positive outcomes. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
Staging of argyrophilic grains: an age-associated tauopathy
50/100 ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology
Key finding: Thus, we propose the following staging paradigm: stage I: AGs restricted to the ambient gyrus and its vicinity; stage II: AGs more apparent in the anterior and posterior medial temporal lobe, including the temporal pole, as well as the subiculum and entorhinal cortex; and stage III: abundant AGs in the septum, insular cortex, and anterior cingulate gyrus, accompanying spongy degeneration of the ambient gyrus. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
44/100 ✓ Peer-reviewed Inflammation and the immune system Journal of neuropathology and experimental neurology
Key finding: COX exists as constitutive and inducible isoforms. +3 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
58/100 ✓ Peer-reviewed Brain tissue and pathology Lancet (London, England)
Key finding: These findings prompted us to screen for multiplication of the SNCA locus in nine families in whom parkinsonism segregates as an autosomal dominant trait. +3 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
MRI and CSF studies in the early diagnosis of Alzheimer's disease
51/100 ✓ Peer-reviewed Mild cognitive impairment Journal of internal medicine
Key finding: In cross-section and longitudinally, our results show that evaluations of the P-tau231 level are highly correlated with reductions in the MRI hippocampal volume and by using CSF and MRI measures together one improves the separation of NL and MCI. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Clinicopathological correlates in frontotemporal dementia
58/100 ✓ Peer-reviewed Lewy body dementia Annals of neurology
Key finding: Behavioral symptoms and semantic dementia were associated with a range of pathologies. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity
43/100 ✓ Peer-reviewed Risk factors Anesthesiology
Key finding: Inhaled anesthetics enhance oligomerization and cytotoxicity of Alzheimer disease-associated peptides. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort
63/100 ✓ Peer-reviewed How common it is Neurology
Key finding: Older age is associated with increased HAD in this HIV-1 cohort. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
Walking and dementia in physically capable elderly men
62/100 ✓ Peer-reviewed How common it is JAMA
Key finding: Promoting active lifestyles in physically capable men could help late-life cognitive function. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Rural practitioners' experiences in dementia diagnosis and treatment
37/100 ✓ Peer-reviewed Disparities Aging & mental health
Key finding: Limitations in access to consultants and limited or non-existent community support and education resources were major impediments to diagnosis and treatment, respectively. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Methods and demographic findings of the baseline survey of the NEDICES cohort: a door-to-door survey of neurological disorders in three communities from Central Spain
49/100 ✓ Peer-reviewed Disparities Public health
Key finding: Participation rates were good in both phases of the NEDICES baseline study, and this was influenced by age, sex and setting of the participants. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
A systematic review of the association between the Behavioral and Psychological Symptoms of Dementia and burden of care
59/100 ✓ Peer-reviewed Caregiving International psychogeriatrics
Key finding: The results of this review support, but do not conclusively establish, the association between BPSD and PSC. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
PET imaging of amyloid in Alzheimer's disease
50/100 ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology
Key finding: When putrescine-gadolinium-Abeta has been injected into transgenic mice overexpressing amyloid, labelling has been observed with MRI. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-09-01
Mild cognitive impairment as a diagnostic entity
57/100 ✓ Peer-reviewed Getting a diagnosis Journal of internal medicine
Key finding: It is suggested that the diagnosis of MCI can be made in a fashion similar to the clinical diagnoses of dementia and AD.
Full summary, score breakdown and related studies → Original source
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2004-09-01
Cognitive reserve: implications for diagnosis and prevention of Alzheimer's disease
43/100 ✓ Peer-reviewed Prevention and risk Current neurology and neuroscience reports
Key finding: Epidemiologic evidence suggests that higher occupational attainment and education, as well as increased participation in intellectual, social, and physical aspects of daily life, are associated with slower cognitive decline in healthy elderly and may reduce the risk of incident Alzheimer's disease (AD). +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-09-01
APOE and cognitive decline in preclinical Alzheimer disease and non-demented aging
48/100 ✓ Peer-reviewed Genetics Neurology
Key finding: Although possession of the APOE epsilon4 allele is a risk factor for AD in old age, it does not modify the progression of the disease during the preclinical period.
Full summary, score breakdown and related studies → Original source
August 2004 8
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2004-08-30
Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration
52/100 ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America
Key finding: Apoptotic nerve cell death is implicated in the pathogenesis of several devastating neurodegenerative conditions, including glaucoma and Alzheimer's and Parkinson's diseases. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-08-27
Using Health Utility Index (HUI) for measuring the impact on health-related quality of Life (HRQL) among individuals with chronic diseases
42/100 ✓ Peer-reviewed Digital health tools TheScientificWorldJournal
Key finding: The Health Utilities Index (HUI) is a recently developed system for measuring the overall health status and health-related quality of life (HRQL) of individuals, clinical groups, and general populations. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-08-26
Combined anticoagulant-antiplatelet use and major bleeding events in elderly atrial fibrillation patients
55/100 ✓ Peer-reviewed Vascular contributions Stroke
Key finding: Although concerns about increased bleeding risk with combined warfarin-antiplatelet therapy are not unfounded, the risk of bleeding is moderately increased. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-08-26
Quality of life after stroke: the North East Melbourne Stroke Incidence Study (NEMESIS)
40/100 ✓ Peer-reviewed Vascular contributions Stroke
Key finding: A substantial proportion of stroke survivors have very poor HRQoL. +1 more finding
Full summary, score breakdown and related studies → Original source
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2004-08-20
Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
63/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Internal Medicine
Key finding: The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. +4 more findings
Full summary, score breakdown and related studies → Original source
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2004-08-19
Decreased brain dopaminergic transporters in HIV-associated dementia patients
44/100 ✓ Peer-reviewed Caregiving Brain : a journal of neurology
Key finding: HIV patients with associated dementia (HAD), but not those without dementia (ND) had significantly lower DAT availability in putamen (-19.3%, P = 0.009) and ventral striatum (-13.6%, P = 0.03) compared with seronegative controls. +2 more findings
Full summary, score breakdown and related studies → Original source
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2004-08-15
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
52/100 ✓ Peer-reviewed Brain tissue and pathology Nature neuroscience
Key finding: In contrast to Alzheimer disease (AD), the brains of those affected by hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D) show few parenchymal amyloid plaques. +3 more findings
Full summary, score breakdown and related studies → Original source
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2004-08-10
Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study
43/100 ✓ Peer-reviewed Prevention and risk BMJ
Key finding: Participants who drank no alcohol at midlife and those who drank alcohol frequently were both twice as likely to have mild cognitive impairment in old age as those participants who drank alcohol infrequently. +4 more findings
Full summary, score breakdown and related studies → Original source
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