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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,351–24,375 of 27,380 studies, newest first · page 975 of 1096.

October 2003 12

  1. 2003-10-01

    Tissue-specific expression patterns of the RAGE receptor and its soluble forms--a result of regulated alternative splicing?

    ✓ Peer-reviewed Disease mechanisms Biochimica et biophysica acta

    Key finding: The receptor for advanced glycation end products (RAGE) is known to be causally involved in a variety of pathophysiological processes, e.g. immune/inflammatory disorders, Alzheimer disease, tumors, and abnormalities associated with diabetes as arteriosclerosis or disordered wound healing.

    Full summary, score breakdown and related studies → Original source

  2. 2003-10-01

    Astrocyte infection by HIV-1: mechanisms of restricted virus replication, and role in the pathogenesis of HIV-1-associated dementia

    ✓ Peer-reviewed Inflammation and the immune system Current HIV research

    Key finding: Studies of post-mortem brain tissue samples from individuals with AIDS have revealed that a small proportion of astrocytes are infected by HIV-1 which is linked to the development of HIV-associated dementia (HIVD), a frequent clinical manifestation of HIV-1 disease affecting up to 20% of infected adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-10-01

    Elevated neurofilament levels in neurological diseases

    ✓ Peer-reviewed Brain tissue and pathology Brain research

    Key finding: By means of a new sensitive ELISA capable of measuring 60 ng/l of neurofilament light, significant elevations were observed for different neurological disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2003-10-01

    Cognitive, psychiatric and motor response to galantamine in Parkinson's disease with dementia

    ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry

    Key finding: Cholinesterase inhibitors with additional nicotinic activity, such as galantamine, may be useful in PD patients with dementia (PDD) since stimulation of nicotinic receptors may prevent the down-regulation that is likely to accompany cholinesterase inhibition and facilitate dopamine release in the striatum. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-10-01

    Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study

    ✓ Peer-reviewed Cognitive tests and assessment Lancet (London, England)

    Key finding: We used multiple MRI scans to measure progression of cerebral atrophy in 12 patients with Alzheimer's disease who were followed up from a presymptomatic stage through to moderately severe dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2003-10-01

    A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation

    ✓ Peer-reviewed Risk genes beyond APOE Brain pathology (Zurich, Switzerland)

    Key finding: Adenosine A1 receptor (A1R) immunoreactivity was found in degenerating neurons with neurofibrillary tangles and in dystrophic neurites of senile plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-10-01

    Risk factors for mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 2

    ✓ Peer-reviewed How common it is Archives of neurology

    Key finding: The development of MCI is associated with measurements of cognition and depression, racial and constitutional factors, and cerebrovascular disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2003-10-01

    Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1

    ✓ Peer-reviewed How common it is Archives of neurology

    Key finding: Twenty-two percent of the participants aged 75 years or older had MCI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2003-10-01

    Anger and depression management: psychoeducational skill training interventions for women caregivers of a relative with dementia

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Significant main effects in the expected direction were found for changes in most of these measures. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-10-01

    The Mini-Cog as a screen for dementia: validation in a population-based sample

    ✓ Peer-reviewed Getting a diagnosis Journal of the American Geriatrics Society

    Key finding: When applied post hoc to an existing population, the Mini-Cog was as effective in detecting dementia as longer screening and assessment instruments. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2003-10-01

    CSF markers for incipient Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: Early diagnosis of Alzheimer's disease (AD) is needed to initiate symptomatic treatment with acetylcholinesterase inhibitors, and will be of even greater significance if drugs aimed at slowing down the degenerative process, such as vaccination regimes and beta-secretase and gamma-secretase inhibitors, prove to affect AD pathology and to have clinical effect. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2003-10-01

    Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial

    ✓ Peer-reviewed Treatments JAMA

    Key finding: Exercise training for patients with Alzheimer disease combined with teaching caregivers how to manage behavioral problems may help decrease the frailty and behavioral impairment that are often prevalent in patients with Alzheimer disease.

    Full summary, score breakdown and related studies → Original source

September 2003 13

  1. 2003-09-25

    Circle of willis atherosclerosis is a risk factor for sporadic Alzheimer's disease

    ✓ Peer-reviewed Risk factors Arteriosclerosis, thrombosis, and vascular biology

    Key finding: We conducted a quantitative investigation of brain arterial atherosclerotic damage and its relationship to sporadic Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-09-11

    Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial

    ✓ Peer-reviewed Vascular contributions Stroke

    Key finding: These data demonstrate that donepezil is an effective and well-tolerated treatment for VaD and show it may have an important place in the management of this condition. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-09-04

    Measuring inconsistency in meta-analyses

    ✓ Peer-reviewed Cognitive tests and assessment BMJ

    Cochrane Reviews have recently started including the quantity I(2) to help readers assess the consistency of the results of studies in meta-analyses.

    Full summary, score breakdown and related studies → Original source

  4. 2003-09-01

    Including older people with dementia in research: Challenges and strategies

    ✓ Peer-reviewed Digital health tools Aging & Mental Health

    Key finding: The researchers also conclude that the use of observation and interview are 'meaning-making occasions' which are qualitatively different but equally valuable for understanding quality of life in care settings.

    Full summary, score breakdown and related studies → Original source

  5. 2003-09 month only

    Hypertension, hypertension-clustering factors and Alzheimer's disease

    ✓ Peer-reviewed Risk factors Neurological research

    Key finding: Even if hypertension only results in a moderately increased risk of AD, or overall dementia, better treatment of hypertension may have an immense effect on the total numbr of demented individuals.

    Full summary, score breakdown and related studies → Original source

  6. 2003-09-01

    Effect of multicomponent interventions on caregiver burden and depression: the REACH multisite initiative at 6-month follow-up

    ✓ Peer-reviewed Caregiving Psychology and aging

    Key finding: Meta-analysis was used to examine pooled parameter estimates of 9 active compared with 6 control conditions of the Resources for Enhancing Alzheimer's Caregiver Health (REACH) project at 6 months on caregiver burden and depressive symptoms. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-09-01

    Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals

    ✓ Peer-reviewed Prevention and risk The American journal of clinical nutrition

    Key finding: Regular consumption of fruit and vegetables is associated with reduced risks of cancer, cardiovascular disease, stroke, Alzheimer disease, cataracts, and some of the functional declines associated with aging. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2003-09-01

    DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration

    ✓ Peer-reviewed Risk factors Toxicologic pathology

    Key finding: Olfactory bulb and hippocampal AP sites were significantly higher in exposed than in control age matched animals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2003-09-01

    Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease: a meta-analysis

    ✓ Peer-reviewed Treatments CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    Key finding: Treatment with ChEIs results in a modest but significant therapeutic effect and modestly but significantly higher rates of adverse events and discontinuation of treatment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2003-09-01

    The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence

    ✓ Peer-reviewed Treatments International journal of geriatric psychiatry

    Key finding: We suggest that glutamate receptors of the N-methyl-D-aspartate (NMDA) type are overactivated in a tonic rather than a phasic manner in this disorder. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2003-09-01

    Treatment of Alzheimer's disease: current status and new perspectives

    ✓ Peer-reviewed Treatments The Lancet. Neurology

    Key finding: Pharmacological treatment of AD is based on the use of acetylcholinesterase inhibitors, which have beneficial effects on cognitive, functional, and behavioural symptoms of the disease, but their role in AD pathogenesis is unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2003-09-01

    Nitration of tau protein is linked to neurodegeneration in tauopathies

    ✓ Peer-reviewed Drug development The American journal of pathology

    Key finding: Immunohistochemistry (IHC) showed that n847 labeled neurons in the hippocampus and neocortex of AD and DS brains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2003-09-01

    Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta

    ✓ Peer-reviewed Treatments Brain research. Brain research reviews

    Key finding: The coordination of Cu appears to be crucial for Abeta's own antioxidant activity that has been demonstrated both in vitro as well as in the brain, cerebrospinal fluid and plasma. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →