Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,476–23,500 of 27,380 studies, newest first · page 940 of 1096.

October 2005 24

  1. 2005-10-01

    Mitochondria take center stage in aging and neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Annals of neurology

    Key finding: Much of the evidence has been correlative, but recent evidence has shown that the accumulation of mitochondrial DNA mutations accelerates normal aging, leads to oxidative damage to nuclear DNA, and impairs gene transcription. +1 more finding

  2. 2005-10-01

    Nonlinear dynamical analysis of EEG and MEG: review of an emerging field

    ✓ Peer-reviewed Brain scans and imaging Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    Key finding: Interpretation of these results in terms of 'functional sources' and 'functional networks' allows the identification of three basic patterns of brain dynamics: (i) normal, ongoing dynamics during a no-task, resting state in healthy subjects; this state is characterized by a high dimensional complexity and a relatively low and fluctuating level of synchronization of the neuronal networks; (ii) hypersynchronous, highly nonlinear dynamics of epileptic seizures; (iii) dynamics of degenerative encephalopathies with an abnormally low level of between area synchronization. +1 more finding

  3. 2005-10-01

    Ribosome dysfunction is an early event in Alzheimer's disease

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In the present study, we report that in multiple cortical areas of MCI and AD subjects, there is a significant impairment in ribosome function that is not observed in the cerebellum of the same subjects. +2 more findings

  4. 2005-10-01

    Central obesity and the aging brain

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of neurology

    Key finding: A larger WHR may be related to neurodegenerative, vascular, or metabolic processes that affect brain structures underlying cognitive decline and dementia. +2 more findings

  5. 2005-10-01

    Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly

    ✓ Peer-reviewed Hippocampus size on brain scans Neuroscience research

    Key finding: In these animals, BDNF mRNA levels were significantly decreased in the hippocampus after 6 h of restraint, but the ability of restraint to reduce BDNF synthesis seemed less robust than that seen in acute stress models.

  6. 2005-10-01

    The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death

    ✓ Peer-reviewed Disease mechanisms Current Alzheimer research

    Key finding: Neuronal loss is associated with Alzheimer's disease (AD).

  7. 2005-10-01

    Enhanced neurofibrillary tangle formation, cerebral atrophy, and cognitive deficits induced by repetitive mild brain injury in a transgenic tauopathy mouse model

    ✓ Peer-reviewed Disease mechanisms Journal of neurotrauma

    Key finding: Previous study showed that mild rTBI (mrTBI) accelerated the deposition of Abeta in the brains of transgenic (Tg) mice (Tg2576) that over-express human Abeta precursor proteins with the familial AD Swedish mutations (APP695swe) and model of AD-like amyloidosis. +2 more findings

  8. 2005-10-01

    Long-Term Care in the St. John's Region: Impact of Single Entry and Prediction of Bed Need

    ✓ Peer-reviewed Health systems and care delivery Healthcare Management Forum

    Key finding: It was concluded that the single entry system was associated with improved appropriateness of NH bed utilization.

  9. 2005-10-01

    Introduction: Dementia Care and Quality of Life in Assisted Living and Nursing Homes

    ✓ Peer-reviewed Health systems and care delivery The Gerontologist

    Key finding: Recent estimates indicate that 23% to 42% of RC/AL residents have moderate or severe dementia, as do more than 50% of nursing home residents (Zimmerman et al., 2003). +1 more finding

  10. 2005-10-01

    Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neurology, neurosurgery, and psychiatry

    Key finding: We investigated consecutive patients with dementia. +3 more findings

  11. 2005-10-01
  12. 2005-10-01

    Alcohol consumption and cognitive function in late life: a longitudinal community study

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Cognitive functions and self-reported drinking habits were assessed at 2-year intervals over an average of 7 years of follow-up. +3 more findings

  13. 2005-10-01

    Delusions and hallucinations are associated with worse outcome in Alzheimer disease

    ✓ Peer-reviewed Cognitive tests and assessment Archives of neurology

    Key finding: According to all previous literature, they are not associated with mortality. +3 more findings

  14. 2005-10-01

    A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of clinical investigation

    Key finding: Here we report that, in cytokine-stressed human neural cells, DHA attenuates amyloid-beta (Abeta) secretion, an effect accompanied by the formation of NPD1, a novel, DHA-derived 10,17S-docosatriene. +3 more findings

  15. 2005-10-01

    Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage

    Key finding: Regions of significant GM loss over the 18-month follow-up period common to both converters and non-converters included the temporal neocortex, parahippocampal cortex, orbitofrontal and inferior parietal areas, and the left thalamus. +2 more findings

  16. 2005-10-01

    A systematic review of prevalence studies of dementia in Parkinson's disease

    ✓ Peer-reviewed How common it is Movement disorders : official journal of the Movement Disorder Society

    Key finding: There were significant methodological variations between studies and in the four studies that matched the quality criteria most closely, the rate of PDD was 31.1% (20.1-42.1). +1 more finding

  17. 2005-10-01

    Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: During follow-up, 13 healthy patients converted to MCI or Alzheimer disease (AD), whereas 39 MCI subjects converted to AD. +4 more findings

  18. 2005-10-01

    Association between recurrent concussion and late-life cognitive impairment in retired professional football players

    ✓ Peer-reviewed Getting a diagnosis Neurosurgery

    Key finding: Our findings suggest that the onset of dementia-related syndromes may be initiated by repetitive cerebral concussions in professional football players. +4 more findings

  19. 2005-10-01

    Delayed neurotoxicity in primary central nervous system lymphoma

    ✓ Peer-reviewed Prevention and risk Archives of neurology

    Key finding: The 5-year cumulative incidence of neurotoxicity was 24%; this incidence increases over time. +3 more findings

  20. 2005-10-01

    Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease

    ✓ Peer-reviewed Prevention and risk Archives of neurology

    Key finding: Obesity at midlife is associated with an increased risk of dementia and AD later in life. +2 more findings

  21. 2005-10-01

    Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: Inflammation has been implicated as a pathogenetic factor in Alzheimer disease, possibly via effects on beta-amyloid (Abeta).

  22. 2005-10-01
  23. 2005-10-01

    Serum cholesterol and risk of Alzheimer disease: a community-based cohort study

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The data do not support an association between serum total cholesterol or high density lipoprotein in late life and subsequent risk of dementia or Alzheimer disease (AD). +4 more findings

  24. 2005-10-01

    Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET

    ✓ Peer-reviewed Genetics Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: (18)F-FDG PET of cerebral glucose metabolism is a valuable diagnostic tool for the prediction of clinical outcome in individual MCI patients. +3 more findings

September 2005 1

  1. 2005-09-30

    Segmented hippocampal volume in children and adolescents with posttraumatic stress disorder

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Future longitudinal studies with trauma control subjects and neuropsychological measures are indicated to further elucidate the relationship between hippocampus and behavioral abnormalities in young PTSD subjects. +2 more findings

Browse the library by subject, with the full score breakdown →