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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,751–23,775 of 27,380 studies, newest first · page 951 of 1096.

March 2005 17

  1. 2005-03-01

    Beyond the global score of the Zarit Burden Interview: useful dimensions for clinicians

    ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry

    Key finding: The purpose of this study was to explore the structure of the Zarit Burden Interview (ZBI) for informal caregivers of patients suffering from AD or related disorders, and to examine the relations of the dimensions found with functional disabilities and other patient health indicators. +3 more findings

  2. 2005-03-01

    Use of the QOL-AD for measuring quality of life in people with severe dementia--the LASER-AD study

    ✓ Peer-reviewed Cognitive tests and assessment Age and ageing

    Key finding: Health-related quality of life (HR-QOL) scales are particularly important in older people as global outcome measures for interventions. +3 more findings

  3. 2005-03-01

    Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of disease

    Key finding: Our group has recently established the molecular background of PLOSL by identifying mutations in DAP12 and TREM2 genes. +3 more findings

  4. 2005-03-01

    Glia and their cytokines in progression of neurodegeneration

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: All of these conditions are associated with early and often dramatic activation of, and cytokine overexpression in, microglia and astrocytes, sometimes decades before pathological changes consistent with a diagnosis of Alzheimer's disease are apparent, as in patients with Down's syndrome or head injury. +3 more findings

  5. 2005-03-01

    Tau and alpha-synuclein inclusions in a case of familial frontotemporal dementia and progressive aphasia

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neuropathology and experimental neurology

    Key finding: Recent studies have shown that neurofibrillary tangles are frequently accompanied by alpha-synuclein inclusions in sporadic and familial Alzheimer disease, in Down syndrome, in progressive supranuclear palsy, and Parkinsonism dementia complex of Guam. +1 more finding

  6. 2005-03-01

    Learning and memory as a function of age in Down syndrome: a study using animal-based tasks

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in neuro-psychopharmacology & biological psychiatry

    Key finding: When considering age as the only clinical variable to parallel the animal studies, age was significantly correlated with performance on object memory and marginally related to performance on reversal learning and spatial memory. +2 more findings

  7. 2005-03-01

    Alzheimer disease and Down syndrome: factors in pathogenesis

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neurobiology of aging

    Key finding: There is evidence to suggest that certain shared features exist in the pathogenesis of vascular disease and Alzheimer disease (AD) in the general population.

  8. 2005-03-01

    Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression

    ✓ Peer-reviewed Risk factors The British journal of psychiatry : the journal of mental science

    Key finding: Although reduced hippocampal volumes are most pronounced in late-onset depression, older people with early-onset disorders also display volume changes and memory loss. +2 more findings

  9. 2005-03-01

    Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Nondemented individuals exhibit a slow rate of whole-brain atrophy from early in adulthood with white-matter loss beginning in middle age; in older adults, the onset of dementia of the Alzheimer type is associated with a markedly accelerated atrophy rate. +1 more finding

  10. 2005-03-01

    Cardiovascular death in rheumatoid arthritis: a population-based study

    ✓ Peer-reviewed How common it is Arthritis and rheumatism

    Key finding: These results indicate that markers of systemic inflammation confer a statistically significant additional risk for cardiovascular death among patients with RA, even after controlling for traditional cardiovascular risk factors and comorbidities. +2 more findings

  11. 2005-03-01

    Albumin, length of stay, and proton pump inhibitors: key factors in Clostridium difficile-associated disease in nursing home patients

    ✓ Peer-reviewed Disparities Journal of the American Medical Directors Association

    Key finding: These findings may facilitate the timely and efficient management of CDAD in nursing home patients. +1 more finding

  12. 2005-03-01

    Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu

    ✓ Peer-reviewed Disparities Archives of neurology

    Key finding: Prevalence of dementia subtypes in China is comparable with that in Western countries.

  13. 2005-03-01

    Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology

    ⚠ Report — not peer-reviewed Caregiving Health technology assessment (Winchester, England)

    Key finding: Further research with DEMQOL is needed to confirm these findings in an independent sample, evaluate responsiveness, investigate the feasibility of use in specific subgroups and in economic evaluation, and develop population norms. +1 more finding

    Scored 40 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

  14. 2005-03-01
  15. 2005-03-01

    DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Higher baseline hippocampal diffusivity was associated with a greater risk of progression to AD in aMCI (p = 0.002).

  16. 2005-03-01
  17. 2005-03-01

    A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Epidemiological studies suggest that increased intake of the omega-3 (n-3) polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with reduced risk of Alzheimer's disease (AD). +4 more findings

February 2005 8

  1. 2005-02-28

    Deaths: preliminary data for 2003

    ✓ Peer-reviewed Risk factors PubMed

    Key finding: The age-adjusted death rate for the United States decreased from 845.3 deaths per 100,000 population in 2002 to 831.2 deaths per 100,000 population in 2003. +3 more findings

  2. 2005-02-24

    Mechanisms, pathophysiology, and therapy of arterial stiffness

    ✓ Peer-reviewed Prevention and risk Arteriosclerosis, thrombosis, and vascular biology

    Key finding: Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular events, dementia, and death.

  3. 2005-02-18

    Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial

    ✓ Peer-reviewed Treatments BMJ (Clinical research ed.)

    Key finding: Neither quetiapine nor rivastigmine are effective in the treatment of agitation in people with dementia in institutional care. +3 more findings

  4. 2005-02-18

    BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: The amyloid precursor protein binds copper and zinc in its extracellular domain, and the Abeta peptides also bind copper, zinc, and iron. +3 more findings

  5. 2005-02-17

    Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: It has been reported that statins reduce the risk of developing the disorder, and a link between cholesterol and Alzheimer disease pathophysiology has been proposed. +3 more findings

  6. 2005-02-11

    Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Presenilin 1 (PS1) is known to be essential for the stability, interaction, and trafficking of the other PS1/gamma-secretase components. +3 more findings

  7. 2005-02-04

    Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The recently developed ultrasensitive bio-barcode assay was used to measure the concentration of amyloid-beta-derived diffusible ligands (ADDLs), a potential soluble pathogenic Alzheimer's disease (AD) marker, in the cerebrospinal fluid (CSF) of 30 individuals. +3 more findings

  8. 2005-02-01

    Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In pharmacological experiments, we found that G-protein coupling and CB1 receptor protein expression are markedly decreased in AD brains. +1 more finding

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