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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,501–23,525 of 27,380 studies, newest first · page 941 of 1096.

September 2005 25

  1. 2005-09-30

    Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

    ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences

    Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge.

    Full summary, score breakdown and related studies → Original source

  2. 2005-09-29

    Neuroanatomical correlates of behavioural disorders in dementia

    ✓ Peer-reviewed Clinical safety Brain : a journal of neurology

    Key finding: Neurodegenerative diseases are associated with profound changes in social and emotional function. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2005-09-29

    Drug discovery from medicinal plants

    ✓ Peer-reviewed Treatments Life sciences

    Key finding: Medicinal plant drug discovery continues to provide new and important leads against various pharmacological targets including cancer, HIV/AIDS, Alzheimer's, malaria, and pain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2005-09-28

    Social reasoning, emotion and empathy in frontotemporal dementia

    ✓ Peer-reviewed Caregiving Neuropsychologia

    Key finding: It appears that social reasoning is disrupted in a number of ways in fvFTD, and the findings provide a basis for the understanding and further study of abnormal behaviour in this disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2005-09-23

    SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

    ✓ Peer-reviewed Inflammation and the immune system The Journal of biological chemistry

    Key finding: Here we demonstrate that NF-kappaB signaling in microglia is critically involved in neuronal death induced by amyloid-beta (Abeta) peptides, which are widely presumed to cause Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2005-09-22

    A new visual rating scale to assess strategic white matter hyperintensities within cholinergic pathways in dementia

    ✓ Peer-reviewed Brain scans and imaging Stroke

    Key finding: The new MRI rating scale for WMH in cholinergic pathways is reliable and shows stronger correlations with cognitive performance than a general WMH rating scale in AD with WMH. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2005-09-21

    In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

    ✓ Peer-reviewed Lewy body dementia Neurobiology of disease

    Key finding: Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder associated with akinesia, tremor and rigidity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2005-09-15

    Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-β Peptides

    ✓ Peer-reviewed How common it is Journal of Biological Chemistry

    Key finding: Several epidemiological studies indicate that moderate consumption of wine is associated with a lower incidence of Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2005-09-14

    Structure-function correlates of cognitive decline in aging

    ✓ Peer-reviewed Hippocampus size on brain scans Cerebral cortex (New York, N.Y. : 1991)

    Key finding: Analysis of structural and diffusion tensor imaging (DTI) revealed a heterogeneous set of differences associated with cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2005-09-09

    Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Whether deficiency in ACE activity, arising from genetic alteration or pharmacological inhibition, can decrease Abeta degradation and allow Abeta accumulation in intact cells is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2005-09-08

    Discovering statistically significant pathways in expression profiling studies

    ✓ Peer-reviewed Risk factors Proceedings of the National Academy of Sciences

    Key finding: In particular, it is shown that the differences in the correlation structure of each set of genes can lead to a biased comparison among gene sets unless a normalization procedure is applied. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2005-09-08

    Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss

    ✓ Peer-reviewed Drug development Stroke

    Key finding: Our results showed a relationship between arterial stiffness and cognitive impairment, suggesting that functional changes of the arterial system could be involved in the onset of dementia (VaD or AD types). +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2005-09-08

    RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Generation of Abeta involves beta-secretase and gamma-secretase activities and is regulated by membrane trafficking of the proteins involved in Abeta production. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2005-09-07

    Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Overexpression of sorLA in neurons causes redistribution of APP to the Golgi and decreased processing to Abeta, whereas ablation of sorLA expression in knockout mice results in increased levels of Abeta in the brain similar to the situation in AD patients.

    Full summary, score breakdown and related studies → Original source

  15. 2005-09-01

    Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Although amyloid precursor protein processing appeared unaffected, we find that LPS significantly induced tau hyperphosphorylation at specific sites that were mediated by the activation of cyclin-dependent kinase 5 (cdk5) through increased formation of the p25 fragment.

    Full summary, score breakdown and related studies → Original source

  16. 2005-09-01

    Endothelial/pericyte interactions

    ✓ Peer-reviewed Vascular contributions Circulation research

    Key finding: Failure of the interactions between the 2 cell types, as seen in numerous genetic mouse models, results in severe and often lethal cardiovascular defects.

    Full summary, score breakdown and related studies → Original source

  17. 2005-09-01

    Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of affective disorders

    Key finding: These findings are consistent with smaller hippocampal volume in adult subjects with chronic PTSD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2005-09-01

    Prognosis of depression in old age compared to middle age: a systematic review of comparative studies

    ✓ Peer-reviewed Brain tissue and pathology The American journal of psychiatry

    Key finding: Depression in old age has a poor long-term prognosis; equal evidence shows that the same is true of depression in middle age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2005-09-01

    Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: Because cardiovascular (CV) risk factors have been associated with declines in cognitive functions and late life dementia, CV risk factors should also be associated with brain atrophy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2005-09-01

    Subjective memory complaints in Chinese subjects with mild cognitive impairment and early Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry

    Key finding: Mild cognitive impairment (MCI) represents a transitional state between normal aging and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2005-09-01

    Daytime sleepiness in mild and moderate Alzheimer's disease and its relationship with cognitive impairment

    ✓ Peer-reviewed Cognitive tests and assessment Journal of sleep research

    Key finding: The aim of this study was to assess daytime sleep propensity in a cohort of patients with mild/moderate AD and to correlate it with cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2005-09-01

    Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: Transgenic mice overexpressing the amyloid precursor protein (APP) gene form amyloid plaques that are accompanied by local activation of microglia/macrophages in a manner similar to the human disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2005-09-01

    Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Recent studies suggest that green tea flavonoids may be used for the prevention and treatment of a variety of neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2005-09-01

    Preclinical Alzheimer's disease: diagnosis and prediction of progression

    ✓ Peer-reviewed Mild cognitive impairment The Lancet. Neurology

    Key finding: From the modest but important breakthroughs in the treatment of Alzheimer's disease (AD), diagnostic focus has increasingly shifted to the accurate detection of the earliest phase of the illness.

    Full summary, score breakdown and related studies → Original source

  25. 2005-09-01

    Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP

    ✓ Peer-reviewed Down syndrome and Alzheimer's FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: In adult DS cortex we found that Notch1, Dll1 and Hes1 expression is up-regulated. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →