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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,251–11,275 of 27,780 studies, newest first · page 451 of 1112.

October 2020 25

  1. 2020-10-21

    Ganglion Cell Layer Thinning in Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging Medicina (Kaunas, Lithuania)

    Key finding: Despite several differences, previous works found a significant thinning of GC layer in patients with AD and MCI.

    Full summary, score breakdown and related studies → Original source

  2. 2020-10-21

    Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer

    ✓ Peer-reviewed Risk factors International journal of molecular sciences

    Key finding: BDNF is considered an instructive mediator of functional and structural plasticity in the central nervous system (CNS), influencing dendritic spines and, at least in the hippocampus, the adult neurogenesis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-10-21

    Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Science advances

    Key finding: Overall, these results are a promising step toward a network-based biomarker tool for AD clinical applications.

    Full summary, score breakdown and related studies → Original source

  4. 2020-10-21

    Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-10-19

    Long-term effects of PM 2·5 on neurological disorders in the American Medicare population: a longitudinal cohort study

    ✓ Peer-reviewed Risk factors The Lancet. Planetary health

    Key finding: Between Jan 1, 2000, and Dec 31, 2016, of 63 038 019 individuals who were aged 65 years or older during the study period, we identified 1·0 million cases of Parkinson's disease and 3·4 million cases of Alzheimer's disease and related dementias based on primary and secondary diagnosis billing codes.

    Full summary, score breakdown and related studies → Original source

  6. 2020-10-19

    Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: a meta-analysis

    ✓ Peer-reviewed Vascular contributions Psychological medicine

    Key finding: Our results revealed that both TMS and tDCS elicit a small trans-diagnostic effect on working memory, tDCS also improved attention/vigilance across diagnoses. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-10-19

    Elderly Perception of Distance to the Grocery Store as a Reason for Feeling Food Insecurity—Can Food Policy Limit This?

    ✓ Peer-reviewed Risk factors Nutrients

    Key finding: Reduced food consumption due to the distance from the place of sale, including of fish (24.8%), some fruits (18.9%) and vegetables (15.4%) and beef (17.3%), may contribute to the deterioration of the diet and, as a result, health conditions.

    Full summary, score breakdown and related studies → Original source

  8. 2020-10-19

    EEG microstate complexity for aiding early diagnosis of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Scientific reports

    Key finding: The microstate associated with the frontoparietal working-memory/attention network was altered in AD due to parietal inactivation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2020-10-19

    Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients

    ✓ Peer-reviewed Digital health tools Journal of general internal medicine

    Key finding: We developed machine learning prediction models for post-operative delirium that performed better than chance and are comparable with traditional stepwise logistic regression.

    Full summary, score breakdown and related studies → Original source

  10. 2020-10-19

    The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: MI failed to show an effect on metabolism in FDG-based AD biomarker, but exploratory analysis suggested positive effect on limbic system metabolism. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-10-19

    APOE2 is associated with longevity independent of Alzheimer's disease

    ✓ Peer-reviewed Genetics eLife

    Key finding: Human data (n=24,661) showed APOE2's survival benefit persisted after adjusting for cognitive status, Alzheimer's diagnosis, and cardiovascular factors +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-10-18

    High-resolution functional connectivity of the default mode network in young adults with down syndrome

    ✓ Peer-reviewed Brain scans and imaging Brain imaging and behavior

    Key finding: Studies of resting-state functional connectivity MRI in Alzheimer's disease suggest that disease stage plays a role in functional changes of the default mode network.

    Full summary, score breakdown and related studies → Original source

  13. 2020-10-16

    Black-White Disparities in Moves to Assisted Living and Nursing Homes Among Older Medicare Beneficiaries

    ✓ Peer-reviewed Health systems and care delivery The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Black older adults are less likely to move to assisted living and are more likely to move to a nursing home compared to white older adults. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-10-16

    Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy

    ✓ Peer-reviewed Disease mechanisms Frontiers in molecular neuroscience

    Key finding: Moreover, several AD risk genes (e.g., PICALM , GRN , and BIN1 ) have been associated with dysregulation of AELN in the late-onset sporadic AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2020-10-16

    TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice

    ✓ Peer-reviewed TREM2 and immune genetics Aging

    Key finding: However, the TREM2 induced anti-inflammatory mechanism is still not well known. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-10-16

    Functional connectivity of white matter as a biomarker of cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: The white matter FC decreased in late MCI and AD dementia patients compared to CN participants, and this decrease was correlated with cognitive measures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-10-15

    Higher Dementia Incidence in Older Adults with Poor Visual Acuity

    ✓ Peer-reviewed Risk factors The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Over 68,904 person-years of follow-up, 1,349 participants developed dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-10-15

    Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome

    ✓ Peer-reviewed Hippocampus size on brain scans Annals of neurology

    Key finding: Our comprehensive examination of the genetic evidence for the causal relationships between previously reported risk factors in AD using PRS and MR supports a causal role for education, blood pressure, cholesterol levels, smoking, and diabetes with the AD phenome. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020-10-15

    Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance

    ✓ Peer-reviewed Disease mechanisms European journal of medicinal chemistry

    Key finding: Overall, this work aims to provide a comprehensive and critical overview of small molecules which are being explored as a lead candidate for discovering drugs against tauopathy in AD.

    Full summary, score breakdown and related studies → Original source

  20. 2020-10-14

    Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis

    ✓ Peer-reviewed Drug development Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    Key finding: Our results provide a clue for the hypothesis that autophagy enhancement and apoptosis inhibition may be involved in the effect of semaglutide to protect against Aβ 25-35 . +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2020-10-14

    Advance care planning information intervention for persons with mild dementia and their family caregivers: Impact on end-of-life care decision conflicts

    ✓ Peer-reviewed End-of-life care PloS one

    Key finding: The intervention resulted in significant improvements among persons with dementia and FCGs for knowledge of end-stage dementia treatment (p = .008 and p < .001, respectively), knowledge of ACP (both p < .001), and significant reductions in decisional conflicts (both p < .001).

    Full summary, score breakdown and related studies → Original source

  22. 2020-10-14

    Cognitive Training Using Fully Immersive, Enriched Environment Virtual Reality for Patients With Mild Cognitive Impairment and Mild Dementia: Feasibility and Usability Study

    ✓ Peer-reviewed Prevention trials JMIR serious games

    Key finding: Participants included 10 physiatrists, 6 OTs, and 11 patients with mild cognitive impairment and mild dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-10-14

    The Effects of COVID-19 and Quarantine Measures on the Lifestyles and Mental Health of People Over 60 at Increased Risk of Dementia

    ✓ Peer-reviewed Prevention trials Frontiers in psychiatry

    Key finding: The sample included 55.6% patients with MCI and 56 people with SCD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-10-14

    Microglia in Alzheimer's Disease in the Context of Tau Pathology

    ✓ Peer-reviewed TREM2 and immune genetics Biomolecules

    Key finding: First described more than a century ago, these cells were initially assigned a secondary role in the central nervous system (CNS) with respect to the protagonists, neurons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020-10-14

    Impact of dementia on informal care: a systematic review of family caregivers' perceptions

    ✓ Peer-reviewed Caregiving BMJ supportive & palliative care

    Key finding: Eighty-one studies with 3347 participants were included in this review.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →