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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,376–24,400 of 27,380 studies, newest first · page 976 of 1096.

September 2003 18

  1. 2003-09-01

    Intrathecal inflammation precedes development of Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Journal of neurology, neurosurgery, and psychiatry

    Key finding: These results demonstrate increased production of the proinflammatory cytokine, TNFalpha and decreased production of the anti-inflammatory cytokine TGFbeta in patients with MCI at risk to develop AD, suggesting a propensity towards inflammation in this patient group and indicating that CNS inflammation is a early hallmark in the pathogenesis of AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-09-01

    A longitudinal study of brain morphometrics using quantitative magnetic resonance imaging and difference image analysis

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: Cross-sectional analysis revealed a significant association between age and reduction in all brain volumes except hippocampal volume. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-09-01

    The course of delirium in older medical inpatients: a prospective study

    ✓ Peer-reviewed Clinical safety Journal of general internal medicine

    Key finding: Among patients with and without dementia, symptoms of delirium persist up to 12 months after diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2003-09-01

    Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: The HIV protein Tat is both neurotoxic and proinflammatory; however, its contribution to HIV-related synaptic dysfunction remains unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-09-01

    Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view

    ✓ Peer-reviewed Brain tissue and pathology Journal of neuropathology and experimental neurology

    Key finding: The major clinicopathological manifestations of CAA include cerebral hemorrhage, ischemic lesions, and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2003-09-01

    Cognitive impairment in hip fracture patients: timing of detection and longitudinal follow-up

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: Eight hospitals in Baltimore, Maryland. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-09-01

    Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment The British journal of psychiatry : the journal of mental science

    Key finding: A recent Cochrane review of reality orientation therapy identified the need for large, well-designed, multi-centre trials. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2003-09-01

    Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to P301L and G272V tau mutations

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: Frontotemporal dementia (FTD) is a pathologically heterogeneous group of presenile neurodegenerative disorders, with or without the deposition of hyperphosphorylated tau protein in affected brain regions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2003-09-01

    Cerebrospinal fluid markers in dementia with lewy bodies compared with Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: Most patients with dementia with Lewy bodies (DLB) exhibit diffuse plaque-only pathology with rare neocortical neurofibrillary tangles (NFTs), as opposed to the widespread cortical neurofibrillary-tau involvement in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-09-01

    Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: The antemortem diagnosis of Alzheimer disease (AD) requires time-consuming and costly procedures. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2003-09-01

    Cerebral amyloid angiopathy: pathogenesis and effects on the ageing and Alzheimer brain

    ✓ Peer-reviewed Risk genes beyond APOE Neurological research

    Key finding: Here, the pathogenesis of CAA and its effects on the brain are reviewed and the possible effects of CAA on therapies for Alzheimer's disease are evaluated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2003-09-01

    Progressive worsening of adaptive functions in Down syndrome may be mediated by the complexing of soluble Abeta peptides with the alpha 7 nicotinic acetylcholine receptor: therapeutic implications

    ✓ Peer-reviewed Down syndrome and Alzheimer's Clinical neuropharmacology

    Key finding: In persons with Down syndrome, soluble Abeta peptides, which result from the processing of the amyloid precursor protein, appear in the brain decades before the extracellular deposition of neuritic plaques. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2003-09-01

    Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neuropathology and experimental neurology

    Key finding: These events were followed at a later age, associated with entorhinal neuron loss, by an increase in GAP-43.

    Full summary, score breakdown and related studies → Original source

  14. 2003-09-01

    The Resources for Enhancing Alzheimer's Caregiver Health (REACH): project design and baseline characteristics

    ✓ Peer-reviewed Caregiving Psychology and aging

    Key finding: The purpose of this article is to describe the research design, interventions, and outcome measures used in REACH and to characterize the sample recruited for the study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2003-09-01

    The prevalence and causes of dementia in people under the age of 65 years

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: The study confirms previous "guestimates" of the number of younger people affected by dementia in UK. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2003-09-01

    Dementia as a risk factor for falls and fall injuries among nursing home residents

    ✓ Peer-reviewed Prevention and risk Journal of the American Geriatrics Society

    Key finding: Although most falls do not result in injury, the fact that residents with dementia fall more often than their counterparts without dementia leaves them with a higher overall risk of sustaining injurious falls over time. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2003-09-01

    Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients

    ✓ Peer-reviewed Genetics Experimental neurology

    Key finding: Alternative cleavage of the amyloid precursor protein (APP), occurring in both normal and AD subjects, results in the generation and secretion of soluble APP (sAPP) and Abeta. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2003-09-01

    Neuronal expression of GFAP in patients with Alzheimer pathology and identification of novel GFAP splice forms

    ✓ Peer-reviewed Biomarkers Molecular psychiatry

    Key finding: Intriguingly, this neuronal GFAP is coded by out-of-frame splice variants and its expression is associated with Alzheimer pathology.

    Full summary, score breakdown and related studies → Original source

August 2003 7

  1. 2003-08-27

    Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

    ✓ Peer-reviewed Disease mechanisms Journal of molecular medicine (Berlin, Germany)

    Key finding: As these conditions include Alzheimer's, Parkinson's and the prion diseases, several forms of fatal systemic amyloidosis, and at least one condition associated with medical intervention (haemodialysis), they are of enormous importance in the context of present-day human health and welfare. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-08-22

    Hippocampal abnormalities after prolonged febrile convulsion: a longitudinal MRI study

    ✓ Peer-reviewed Hippocampus size on brain scans Brain : a journal of neurology

    Key finding: Our recently published data on children investigated within 5 days of a PFC showed that children investigated by MRI within 48 h of a PFC had large hippocampal volumes and prolongation of T2 relaxation time. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-08-18

    Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: A molecular basis for memory failure in Alzheimer's disease (AD) has been recently hypothesized, in which a significant role is attributed to small, soluble oligomers of amyloid beta-peptide (A beta). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2003-08-14

    Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Despite the crucial role played by cholesterol and copper in nutrition and normal brain function, recent evidence indicates that they may both be important factors in the etiology of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-08-14

    Impact of viral and bacterial burden on cognitive impairment in elderly persons with cardiovascular diseases

    ✓ Peer-reviewed Cognitive tests and assessment Stroke

    Key finding: We sought to investigate whether the seropositivity of common infections was associated with cognitive function. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2003-08-05

    Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: Compared with controls, the patients showed hypometabolism in several regions that, most notably, included the left anterior insula/frontal opercular region. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-08-01

    Effects of an Automated Telephone Support System on Caregiver Burden and Anxiety: Findings From the REACH for TLC Intervention Study

    ✓ Peer-reviewed Digital health tools The Gerontologist

    Key finding: There was a significant intervention effect as hypothesized for participants with lower mastery at baseline on all three bother (p =.04), anxiety (p =.01), and depression (p =.007). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →