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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,251–21,275 of 27,380 studies, newest first · page 851 of 1096.

October 2009 8

  1. 2009-10-01

    Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Journal of bioenergetics and biomembranes

    Key finding: Positron emission tomography (PET) studies of glucose metabolism revealed decreased energetics in brain of subjects with AD and arguably its earliest form, mild cognitive impairment (MCI), and this decrease correlated with brain structural studies using MRI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2009-10-01

    Relationships between biomarkers in aging and dementia

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Different biomarkers for Alzheimer disease provide different information from one another that is likely to be complementary.

    Full summary, score breakdown and related studies → Original source

  3. 2009-10-01

    Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Nature

    Key finding: Studies using new neuroimaging techniques and fluid biomarkers suggest that Alzheimer's disease pathology can be detected preclinically.

    Full summary, score breakdown and related studies → Original source

  4. 2009-10-01

    Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors

    ✓ Peer-reviewed Getting a diagnosis Alzheimer disease and associated disorders

    Key finding: Overall estimates of diagnostic sensitivity varied among studies and seemed to be in part a function of dementia severity, degree of patient impairment, dementia subtype, and frequency of patient-provider contact.

    Full summary, score breakdown and related studies → Original source

  5. 2009-10-01

    Promising strategies for the prevention of dementia

    ✓ Peer-reviewed Prevention and risk Archives of neurology

    Key finding: In observational studies, vascular risk factors-including diabetes, hypertension, dyslipidemia, and obesity-are fairly consistently associated with increased risk of dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-10-01

    Aerobic fitness is associated with hippocampal volume in elderly humans

    ✓ Peer-reviewed Prevention and risk Hippocampus

    Key finding: Aerobic fitness and exercise are effective at preventing cortical decay and cognitive impairment in older adults and epidemiological studies suggest that physical activity can reduce the risk for developing dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2009-10-01

    MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: The groups of individuals who agreed to participate in the imaging substudies of AD trials were remarkably comparable to the comparison groups at baseline on a wide range of demographic and clinical measures; there seems to be a minimal effect of self-selection bias. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-10-01

    Rates of cognitive change in Alzheimer disease: observations across a decade of placebo-controlled clinical trials with donepezil

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: MMSE decline by week 24 was significantly greater among group 1 (pre-1995) placebo patients versus group 2; a similar trend was observed with the ADAS-cog. +1 more finding

    Full summary, score breakdown and related studies → Original source

September 2009 17

  1. 2009-09-29

    Cerebral amyloidosis: postmortem detection with human 7.0-T MR imaging system

    ✓ Peer-reviewed Down syndrome and Alzheimer's Radiology

    Key finding: The finding of postmortem susceptibility-weighted changes in the cerebral cortex of patients with cerebral amyloidosis with a human 7.0-T MR imaging system opens up the possibility of obtaining in vivo radiologic evidence of cerebral amyloid beta deposition.

    Full summary, score breakdown and related studies → Original source

  2. 2009-09-28

    Trajectories of cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Genetics International psychogeriatrics

    Key finding: Trajectory modeling of longitudinal cognitive and behavioral data may provide enhanced resolution of phenotypic variation in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-09-26

    In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imaging

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: We reported volumes for the subfields and demonstrated differences in the distribution within the hippocampus and its parts. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2009-09-26

    The effects of chronic glucocorticoid exposure on dendritic length, synapse numbers and glial volume in animal models: implications for hippocampal volume reductions in depression

    ✓ Peer-reviewed Hippocampus size on brain scans Physiology & behavior

    Key finding: Although the main purpose of GCs is to restore homeostasis when acutely elevated, animal studies indicate that chronic exposure to these hormones can cause damage to the hippocampus. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2009-09-26

    Evaluation of cerebrospinal fluid tau/beta-amyloid(42) ratio as diagnostic markers for Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers European neurology

    Key finding: Alzheimer's disease (AD) is the leading cause of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-09-25

    Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

    ✓ Peer-reviewed Disease mechanisms Science

    Amyloid-beta (Abeta) accumulation in the brain extracellular space is a hallmark of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  7. 2009-09-25

    Performance of FDG PET for detection of Alzheimer's disease in two independent multicentre samples (NEST-DD and ADNI)

    ✓ Peer-reviewed Long-term cohort studies Dementia and geriatric cognitive disorders

    Key finding: We investigated the performance of FDG PET using an automated procedure for discrimination between Alzheimer's disease (AD) and controls, and studied the influence of demographic and technical factors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-09-24

    Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk The Lancet. Neurology

    Key finding: We identified 22 hospital-based and eight population-based eligible cohorts (7511 patients) described in 73 papers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2009-09-23

    CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation

    ✓ Peer-reviewed Inflammation and the immune system Journal of Neuroscience

    Key finding: We find that cells lacking these receptors could not initiate a Src-Vav-Rac signaling cascade leading to reactive oxygen species production and phagocytosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2009-09-23

    Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism

    ✓ Peer-reviewed Mild cognitive impairment Journal of neurochemistry

    Key finding: Recently, enolase has been shown to possess a variety of different regulatory functions, beyond glycolysis and gluconeogenesis, associated with hypoxia, ischemia, and Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2009-09-22

    Alzheimer's disease as homeostatic responses to age-related myelin breakdown

    ✓ Peer-reviewed Brain tissue and pathology Neurobiology of aging

    Key finding: This hypothesis has been supported by observations that genetic defects in amyloid precursor protein (APP) and presenilin increase Aβ production and cause familial AD (FAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2009-09-22

    Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2

    ✓ Peer-reviewed Down syndrome and Alzheimer's Genes, brain, and behavior

    Key finding: Our results suggest that BACE2 is not involved in the amyloidogenic pathway, cognitive dysfunction or cholinergic degeneration.

    Full summary, score breakdown and related studies → Original source

  13. 2009-09-22

    Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: In recent years, a series of publications have demonstrated a potentially important role for magnetic resonance imaging in the pre-mortem diagnosis of sporadic Creutzfeldt-Jakob disease.

    Full summary, score breakdown and related studies → Original source

  14. 2009-09-21

    Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neuroengineering and rehabilitation

    Key finding: Reliability of quantitative gait assessment while dual-tasking (walking while doing a secondary task such as talking) in people with cognitive impairment is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2009-09-19

    CNS inflammation and macrophage/microglial biology associated with HIV-1 infection

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    Key finding: HIV-1 does not infect neurons directly but induces damage indirectly through the accumulation of activated macrophage/microglia (M/M) cells, some of which are infected, that release neurotoxic mediators including both cellular activation products and viral proteins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2009-09-17

    Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition

    ✓ Peer-reviewed Brain scans and imaging Stroke

    Key finding: Microbleeds (MBs) are commonly observed in Alzheimer disease.

    Full summary, score breakdown and related studies → Original source

  17. 2009-09-16

    Alzheimer's disease amyloid beta-protein and synaptic function

    ✓ Peer-reviewed Disease mechanisms Neuromolecular medicine

    Key finding: Acute treatment with human-derived or chemically prepared soluble A beta that contains certain oligomeric assemblies, potently and selectively disrupts synaptic plasticity causing inhibition of long-term potentiation (LTP) and enhancement of long-term depression (LTD) of glutamatergic transmission. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →