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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,001–21,025 of 27,380 studies, newest first · page 841 of 1096.

February 2010 12

  1. 2010-02-01

    Late-life depression, mild cognitive impairment, and dementia: possible continuum?

    ✓ Peer-reviewed How common it is The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Prevalence and incidence of depressive symptoms or syndromes in MCI vary as a result of different diagnostic criteria and different sampling and assessment procedures. +2 more findings

  2. 2010-02-01

    Primary progressive aphasia: clinicopathological correlations

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: These data suggest an association between a specific PPA variant and an underlying pathology, although many cases of PPA are associated with an unexpected pathology. +1 more finding

  3. 2010-02-01

    Brief cognitive screening instruments: an update

    ✓ Peer-reviewed Getting a diagnosis International journal of geriatric psychiatry

    Key finding: Dementia remains under-diagnosed in the elderly population. +1 more finding

  4. 2010-02-01

    The use of PET in Alzheimer disease

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: In patients with AD, PET can be used to investigate changes in cerebral glucose metabolism, various neurotransmitter systems, neuroinflammation, and the protein aggregates that are characteristic of the disease, notably the amyloid deposits. +4 more findings

  5. 2010-02-01

    Association between acute care and critical illness hospitalization and cognitive function in older adults

    ✓ Peer-reviewed Getting a diagnosis JAMA

    Key finding: During a mean (SD) follow-up of 6.1 (3.2) years, 1601 participants had no hospitalization, 1287 had 1 or more noncritical illness hospitalizations, and 41 had 1 or more critical illness hospitalizations. +3 more findings

  6. 2010-02-01

    The clinical use of structural MRI in Alzheimer disease

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: Atrophy of medial temporal structures is now considered to be a valid diagnostic marker at the mild cognitive impairment stage. +4 more findings

  7. 2010-02-01

    Comparison of topiramate and risperidone for the treatment of behavioral disturbances of patients with Alzheimer disease: a double-blind, randomized clinical trial

    ✓ Peer-reviewed Treatments Journal of clinical psychopharmacology

    Key finding: Forty-eight patients were randomized to treatment with either topiramate or risperidone, and 41 patients (21 of 25 in topiramate group and 20 of 23 in risperidone group) completed the trial. +3 more findings

  8. 2010-02-01

    Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Among caregivers, this small randomized controlled trial found that escitalopram use resulted in improvement in depression, resilience, burden and distress, and quality of life. +3 more findings

  9. 2010-02-01

    A randomized, placebo-controlled trial of latrepirdine in Huntington disease

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: Short-term administration of latrepirdine is well tolerated in patients with HD and may have a beneficial effect on cognition. +2 more findings

  10. 2010-02-01

    Healthy brain aging: role of exercise and physical activity

    ✓ Peer-reviewed Treatments Clinics in geriatric medicine

    Key finding: There is increasing evidence to suggest that physical activity has a protective effect on brain functioning in older people. +1 more finding

  11. 2010-02-01

    Sertraline for the treatment of depression in Alzheimer disease

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Sertraline did not demonstrate efficacy for the treatment depression symptoms in patients with AD. +1 more finding

  12. 2010-02-01

    Correlation of longitudinal cerebrospinal fluid biomarkers with cognitive decline in healthy older adults

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Changes in CSF biomarker levels may identify early neurodegenerative processes of Alzheimer disease. +1 more finding

January 2010 13

  1. 2010-01-29

    Glucagon-like peptide 1 receptor stimulation as a means of neuroprotection

    ✓ Peer-reviewed Drug development British journal of pharmacology

    Key finding: Similar data suggest that the same effects may occur in other peripheral tissues.

  2. 2010-01-27

    Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms New England Journal of Medicine

    This review of Alzheimer's disease assembles a variety of findings relevant to the mechanism of the disease and ties them together using the current understanding of the basis of the loss of cognition: the accumulation of misfolded proteins, which cause oxidative and inflammatory damage to the brain and, ultimately, synaptic dysfunction.

  3. 2010-01-27

    Serum levels of S100B and NSE proteins in Alzheimer's disease patients

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neuroinflammation

    Key finding: Alzheimer's disease is the most common dementia in the elderly, and the potential of peripheral biochemical markers as complementary tools in the neuropsychiatric evaluation of these patients has claimed further attention. +3 more findings

  4. 2010-01-26

    A Drosophila model for TDP-43 proteinopathy

    ✓ Peer-reviewed Brain tissue and pathology Proceedings of the National Academy of Sciences of the United States of America

    Key finding: To test whether increased expression of wide-type human TDP-43 (hTDP-43) may cause neurotoxicity in vivo, we generated transgenic flies expressing hTDP-43 in various neuronal subpopulations. +3 more findings

  5. 2010-01-25

    Management of behavioral problems in Alzheimer's disease

    ✓ Peer-reviewed Treatments International psychogeriatrics

    Key finding: In addition to cognitive and functional decline, diverse behavioral changes manifest with increasing severity over time, presenting significant management challenges for caregivers and health care professionals. +1 more finding

  6. 2010-01-25

    Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

    ✓ Peer-reviewed Genetics NeuroImage

    Key finding: Hierarchical clustering and heat maps were used to analyze the GWAS results and associations are reported at two significance thresholds (p<10(-7) and p<10(-6)). +3 more findings

  7. 2010-01-25

    When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: We conclude that caution should be exerted in inferring age-trajectories from global fit models, e.g. the quadratic model. +1 more finding

  8. 2010-01-25

    Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in neurobiology

    Key finding: Cognitive disabilities in DS appear to result mainly from two pathological processes: neurogenesis impairment and Alzheimer-like degeneration.

  9. 2010-01-21

    Factors associated with prolonged delirium: a systematic review

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: Preliminary findings suggest that some factors may identify those at risk for persistent delirium; however, more research is needed. +4 more findings

  10. 2010-01-20

    Placebo interventions for all clinical conditions

    ✓ Peer-reviewed Risk factors The Cochrane database of systematic reviews

    Key finding: Main results Outcome data were available in 202 out of 234 included trials, investigating 60 clinical conditions.

  11. 2010-01-19

    Nursing home funding -- deal or no deal ? -- an Irish perspective

    ✓ Peer-reviewed Health systems and care delivery Age and Ageing

    Key finding: The costs of illness can be huge; medical bankruptcy is a significant problem in the United States [9].

  12. 2010-01-18

    The dysregulation of intracellular calcium in Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms Cell calcium

    Key finding: Mutations causing FAD also result in the dysregulation of neuronal calcium (Ca2+) handling and may contribute to AD pathogenesis, an idea termed the 'calcium hypothesis' of AD. +2 more findings

  13. 2010-01-18

    Automated 3D mapping of baseline and 12-month associations between three verbal memory measures and hippocampal atrophy in 490 ADNI subjects

    ✓ Peer-reviewed Digital health tools NeuroImage

    Key finding: We observed no significant correlations between delayed recall performance and hippocampal radial distance on any of the three verbal memory measures in NC. +2 more findings

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